Found 2072 results
Bailey PSJ, Ortmann BM, Martinelli AW, Houghton JW, Costa ASH, Burr SP, Antrobus R, Frezza C & Nathan JA (2020) ABHD11 maintains 2-oxoglutarate metabolism by preserving functional lipoylation of the 2-oxoglutarate dehydrogenase complex. Nature Communications 11
Gao K, Cheng M, Zuo X, Lin J, Hoogewijs K, Murphy MP, Fu X-D & Zhang X (2020) Active RNA interference in mitochondria. Cell Res
De Lazzari F, Sandrelli F, Whitworth AJ & Bisaglia M (2020) Antioxidant Therapy in Parkinson’s Disease: Insights from Drosophila melanogaster. Antioxidants 9, 52
De Lazzari F, Sandrelli F, Whitworth AJ & Bisaglia M (2020) Antioxidant Therapy in Parkinson's Disease: Insights from Drosophila melanogaster. Antioxidants (Basel) 9
McMacken G, Lochmüller H, Bansagi B, Pyle A, Lochmüller A, Chinnery PF, Laurie S, Beltran S, Matalonga L & Horvath R (2020) Behr syndrome and hypertrophic cardiomyopathy in a family with a novel UCHL1 deletion. Journal of Neurology
Biner O, Fedor JG, Yin Z & Hirst J (2020) Bottom-up construction of a minimal system for cellular respiration and energy regeneration. ACS Synth Biol
Cunnane SC, Trushina E, Morland C, Prigione A, Casadesus G, Andrews ZB, M Beal F, Bergersen LH, Brinton RD, de la Monte S, Eckert A, Harvey J, Jeggo R, Jhamandas JH, Kann O, la Cour CMannoury, Martin WF, Mithieux G, Moreira PI, Murphy MP, Nave K-A, Nuriel T, Oliet SHR, Saudou F, Mattson MP, Swerdlow RH & Millan MJ (2020) Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing. Nat Rev Drug Discov
Baxter M, Voronkov M, Poolman T, Galli G, Pinali C, Goosey L, Knight A, Krakowiak K, Maidstone R, Iqbal M, Zi M, Prehar S, Cartwright EJ, Gibbs J, Matthews LC, Adamson AD, Humphreys NE, Rebelo-Guiomar P, Minczuk M, Bechtold DA, Loudon A & Ray D (2020) Cardiac mitochondrial function depends on BUD23 mediated ribosome programming. eLife 9
Cortese A, Tozza S, Yau WYan, Rossi S, Beecroft SJ, Jaunmuktane Z, Dyer Z, Ravenscroft G, Lamont PJ, Mossman S, Chancellor A, Maisonobe T, Pereon Y, Cauquil C, Colnaghi S, Mallucci G, Curro R, Tomaselli PJ, Thomas-Black G, Sullivan R, Efthymiou S, Rossor AM, Laura M, Pipis M, Horga A, Polke J, Kaski D, Horvath R, Chinnery PF, Marques W, Tassorelli C, Devigili G, Leonardis L, Wood NW, Bronstein A, Giunti P, Zuchner S, Stojkovic T, Laing N, Roxburgh RH, Houlden H & Reilly MM (2020) Cerebellar ataxia, neuropathy, vestibular areflexia syndrome due to RFC1 repeat expansionAbstract. Brain 143, 480 - 490
van den Ameele J, Fuge J, Pitceathly RDS, Berry S, McIntyre Z, Hanna MG, Lee M & Chinnery PF (2020) Chronic pain is common in mitochondrial disease. Neuromuscul Disord
Zhang X, Xiao H, Liu C, Zhao L, Wang J, Li H, Wang R, Zhu Y, Chen C, Wu X, Lin D, Wang J, Liu X, Qiu W, Yu-Wai-Man P, Ting DS & Lin H (2020) Comparison of macular structural and vascular changes in neuromyelitis optica spectrum disorder and primary open angle glaucoma: a cross-sectional study. Br J Ophthalmol
Park M, Nishimura T, Baeza-Garza CD, Caldwell ST, Pun PBoon Li, Prag HA, Young T, Sauchanka O, Logan A, Forkink M, Gruszczyk AV, Prime TA, Arndt S, Naudi A, Pamplona R, Coughlan MT, Tate M, Ritchie RH, Caicci F, Kaludercic N, Di Lisa F, Smith RAJ, Hartley RC, Murphy MP & Krieg T (2020) Confirmation of the Cardioprotective Effect of MitoGamide in the Diabetic HeartAbstractPurposeMethods and ResultsConclusion. Cardiovascular Drugs and Therapy
Greenway R, Barts N, Henpita C, Brown AP, Rodriguez LArias, Peña CMRodríg, Arndt S, Lau GY, Murphy MP, Wu L, Lin D, Tobler M, Kelley JL & Shaw JH (2020) Convergent evolution of conserved mitochondrial pathways underlies repeated adaptation to extreme environments. Proceedings of the National Academy of Sciences, 202004223
van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernández I, van Eijk KR, Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleó A, Zetterberg H, Nygaard M, Blauwendraat C, Savage JE, Mengel-From J, Moreno-Grau S, Wagner M, Fortea J, Keogh MJ, Blennow K, Skoog I, Friese MA, Pletnikova O, Zulaica M, Lage C, de Rojas I, Riedel-Heller S, Illán-Gala I, Wei W, Jeune B, Orellana A, Bergh FThen, Wang X, Hulsman M, Beker N, Tesi N, Morris CM, Indakoetxea B, Collij LE, Scherer M, Morenas-Rodríguez E, Ironside JW, van Berckel BNM, Alcolea D, Wiendl H, Strickland SL, Pastor P, Rodríguez ERodríguez, Boeve BF, Petersen RC, Ferman TJ, van Gerpen JA, Reinders MJT, Uitti RJ, Tárraga L, Maier W, Dols-Icardo O, Kawalia A, Dalmasso MCarolina, Boada M, Zettl UK, van Schoor NM, Beekman M, Allen M, Masliah E, de Munain ALópez, Pantelyat A, Wszolek ZK, Ross OA, Dickson DW, Graff-Radford NR, Knopman D, Rademakers R, Lemstra AW, Pijnenburg YAL, Scheltens P, Gasser T, Chinnery PF, Hemmer B, Huisman MA, Troncoso J, Moreno F, Nohr EA, Sørensen TIA, Heutink P, Sánchez-Juan P, Posthuma D, Clarimón J, Christensen K, Ertekin-Taner N, Scholz SW, Ramirez A, Ruiz A, Slagboom E, van der Flier WM & Holstege H (2020) Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta Neuropathol
Tate M, Higgins GC, De Blasio MJ, Lindblom R, Prakoso D, Deo M, Kiriazis H, Park M, Baeza-Garza CD, Caldwell ST, Hartley RC, Krieg T, Murphy MP, Coughlan MT & Ritchie RH (2020) Correction to: The Mitochondria-Targeted Methylglyoxal Sequestering Compound, MitoGamide, Is Cardioprotective in the Diabetic Heart. Cardiovasc Drugs Ther
Wei W & Chinnery PF (2020) Cracking the enigma of mitochondrial-DNA variants and cancer. Nature Metabolism 2, 221 - 222
Pala L, Senn HM, Caldwell ST, Prime TA, Warrington S, Bright TP, Prag HA, Wilson C, Murphy MP & Hartley RC (2020) Enhancing the Mitochondrial Uptake of Phosphonium Cations by Carboxylic Acid IncorporationData_Sheet_1.PDFData_Sheet_2.PDF. Frontiers in Chemistry 8
Chouliaras L, Kumar GS, Thomas AJ, Lunnon K, Chinnery PF & O'Brien JT (2020) Epigenetic Regulation in the pathophysiology of Lewy Body Dementia. Prog Neurobiol, 101822
Prag HA, Pala L, Kula-Alwar D, Mulvey JF, Luping D, Beach TE, Booty LM, Hall AR, Logan A, Sauchanka V, Caldwell ST, Robb EL, James AM, Xu Z, Saeb-Parsy K, Hartley RC, Murphy MP & Krieg T (2020) Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo. Cardiovascular Drugs and Therapy
Bugiardini E, Bottani E, Marchet S, Poole OV, Benincá C, Horga A, Woodward C, Lam A, Hargreaves I, Chalasani A, Valerio A, Lamantea E, Venner K, Holton JL, Zeviani M, Houlden H, Quinlivan R, Lamperti C, Hanna MG & Pitceathly RDS (2020) Expanding the molecular and phenotypic spectrum of truncating mutations. Neurol Genet 6, e381
King MS & Kunji ERS (2020) Expression, Purification, and Structural Biology of Membrane Proteins in Saccharomyces cerevisiae (Perez C, and Maier Teds.), Springer US, New York, NY
Stewart JB & Chinnery PF (2020) Extreme heterogeneity of human mitochondrial DNA from organelles to populations. Nature Reviews Genetics
Jedrychowski MP, Lu GZ, Szpyt J, Mariotti M, Garrity R, Paulo JA, Schweppe DK, Laznik-Bogoslavski D, Kazak L, Murphy MP, Gladyshev VN, Gygi SP, Chouchani ET & Spiegelman BM (2020) Facultative protein selenation regulates redox sensitivity, adipose tissue thermogenesis, and obesity. Proc Natl Acad Sci U S A
Fernández-Del-Río L, Kelly ME, Contreras J, Bradley MC, James AM, Murphy MP, Payne GS & Clarke CF (2020) Genes and lipids that impact uptake and assimilation of exogenous coenzyme Q in Saccharomyces cerevisiae. Free Radic Biol Med 154, 105-118
Pontikos N, Arno G, Jurkute N, Schiff E, Ba-Abbad R, Malka S, Gimenez A, Georgiou M, Wright G, Armengol M, Knight H, Katz M, Moosajee M, Yu-Wai-Man P, Moore AT, Michaelides M, Webster AR & Mahroo OA (2020) Genetic Basis of Inherited Retinal Disease in a Molecularly Characterized Cohort of More Than 3000 Families from the United Kingdom. Ophthalmology