Found 1849 results
Signes A, Cerutti R, Dickson AS, Benincá C, Hinchy EC, Ghezzi D, Carrozzo R, Bertini E, Murphy MP, Nathan JA, Viscomi C, Fernandez-Vizarra E & Zeviani M (2019) APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS. EMBO Mol Med 11
Guyatt AL, Brennan RR, Burrows K, Guthrie PAI, Ascione R, Ring SM, Gaunt TR, Pyle A, Cordell HJ, Lawlor DA, Chinnery PF, Hudson G & Rodriguez S (2019) A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts. Hum Genomics 13, 6
Galván-Peña S, Carroll RG, Newman C, Hinchy EC, Palsson-McDermott E, Robinson EK, Covarrubias S, Nadin A, James AM, Haneklaus M, Carpenter S, Kelly VP, Murphy MP, Modis LK & O'Neill LA (2019) Malonylation of GAPDH is an inflammatory signal in macrophages. Nat Commun 10, 338
Bundgaard A, James AM, Gruszczyk AV, Martin J, Murphy MP & Fago A (2019) Metabolic adaptations during extreme anoxia in the turtle heart and their implications for ischemia-reperfusion injury. Sci Rep 9, 2850
Patel R, Coulter LLee, Rimmer J, Parkes M, Chinnery PFrancis & Swift O (2019) Mitochondrial neurogastrointestinal encephalopathy: a clinicopathological mimic of Crohn's disease. BMC Gastroenterol 19, 11
Pinho BR, Reis SD, Hartley RC, Murphy MP & Oliveira JMA (2019) Mitochondrial superoxide generation induces a parkinsonian phenotype in zebrafish and huntingtin aggregation in human cells. Free Radic Biol Med 130, 318-327
Smith AC & Robinson AJ (2019) MitoMiner v4.0: an updated database of mitochondrial localization evidence, phenotypes and diseases. Nucleic Acids Res 47, D1225-D1228
Ruprecht JJ, King MS, Zögg T, Aleksandrova AA, Pardon E, Crichton PG, Steyaert J & Kunji ERS (2019) The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier. Cell 176, 435-447.e15
Ugun-Klusek A, Theodosi TS, Fitzgerald JC, Burté F, Ufer C, Boocock DJ, Yu-Wai-Man P, Bedford L & E Billett E (2019) Monoamine oxidase-A promotes protective autophagy in human SH-SY5Y neuroblastoma cells through Bcl-2 phosphorylation. Redox Biol 20, 167-181
Posse V, Al-Behadili A, Uhler JP, Clausen AR, Reyes A, Zeviani M, Falkenberg M & Gustafsson CM (2019) RNase H1 directs origin-specific initiation of DNA replication in human mitochondria. PLoS Genet 15, e1007781
Booty LM, Gawel JM, Cvetko F, Caldwell ST, Hall AR, Mulvey JF, James AM, Hinchy EC, Prime TA, Arndt S, Benincá C, Bright TP, Clatworthy MR, Ferdinand JR, Prag HA, Logan A, Prudent J, Krieg T, Hartley RC & Murphy MP (2019) Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo. Cell Chem Biol 26, 449-461.e8
Zhang ATianbu, Montgomery MG, Leslie AGW, Cook GM & Walker JE (2019) The structure of the catalytic domain of the ATP synthase from is a target for developing antitubercular drugs. Proc Natl Acad Sci U S A
Kim Y-R, Baek J-I, Kim SHwan, Kim M-A, Lee B, Ryu N, Kim K-H, Choi D-G, Kim H-M, Murphy MP, Macpherson G, Choo Y-S, Bok J, Lee K-Y, Park J-W & Kim U-K (2019) Therapeutic potential of the mitochondria-targeted antioxidant MitoQ in mitochondrial-ROS induced sensorineural hearing loss caused by Idh2 deficiency. Redox Biol 20, 544-555
Jurkute N, Harvey J & Yu-Wai-Man P (2019) Treatment strategies for Leber hereditary optic neuropathy. Curr Opin Neurol 32, 99-104
Mills EL, Pierce KA, Jedrychowski MP, Garrity R, Winther S, Vidoni S, Yoneshiro T, Spinelli JB, Lu GZ, Kazak L, Banks AS, Haigis MC, Kajimura S, Murphy MP, Gygi SP, Clish CB & Chouchani ET (2018) Accumulation of succinate controls activation of adipose tissue thermogenesis. Nature 560, 102-106
Ferguson DCJ, Smerdon GR, Harries LW, Dodd NJF, Murphy MP, Curnow A & Winyard PG (2018) Altered cellular redox homeostasis and redox responses under standard oxygen cell culture conditions versus physioxia. Free Radic Biol Med 126, 322-333
Signes A & Fernandez-Vizarra E (2018) Assembly of mammalian oxidative phosphorylation complexes I-V and supercomplexes. Essays Biochem 62, 255-270
He J, Ford HC, Carroll J, Douglas C, Gonzales E, Ding S, Fearnley IM & Walker JE (2018) Assembly of the membrane domain of ATP synthase in human mitochondria. Proc Natl Acad Sci U S A
Montgomery MG, Gahura O, Leslie AGW, Zíková A & Walker JE (2018) ATP synthase fromhas an elaborated canonical F-domain and conventional catalytic sites. Proc Natl Acad Sci U S A 115, 2102-2107
Kim M, Stepanova A, Niatsetskaya Z, Sosunov S, Arndt S, Murphy MP, Galkin A & Ten VS (2018) Attenuation of oxidative damage by targeting mitochondrial complex I in neonatal hypoxic-ischemic brain injury. Free Radic Biol Med 124, 517-524
Lee JJ, Sanchez-Martinez A, Zarate AMartinez, Benincá C, Mayor U, Clague MJ & Whitworth AJ (2018) Basal mitophagy is widespread inbut minimally affected by loss of Pink1 or parkin. J Cell Biol
Duncan AL, Ruprecht JJ, Kunji ERS & Robinson AJ (2018) Cardiolipin dynamics and binding to conserved residues in the mitochondrial ADP/ATP carrier. Biochim Biophys Acta 1860, 1035-1045
James AM, Smith CL, Smith AC, Robinson AJ, Hoogewijs K & Murphy MP (2018) The Causes and Consequences of Nonenzymatic Protein Acylation. Trends Biochem Sci
Sharma S, Singh P, Fernandez-Vizarra E, Zeviani M, van der Knaap MS & Saran RKumar (2018) Cavitating Leukoencephalopathy With Posterior Predominance Caused by a Deletion in the APOPT1 Gene in an Indian Boy. J Child Neurol 33, 428-431
Rossman MJ, Santos-Parker JR, Steward CAC, Bispham NZ, Cuevas LM, Rosenberg HL, Woodward KA, Chonchol M, Gioscia-Ryan RA, Murphy MP & Seals DR (2018) Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults. Hypertension