Publications

Found 1777 results
2018
He J, Ford HC, Carroll J, Douglas C, Gonzales E, Ding S, Fearnley IM & Walker JE (2018) Assembly of the membrane domain of ATP synthase in human mitochondria. Proc Natl Acad Sci U S A
Montgomery MG, Gahura O, Leslie AGW, Zíková A & Walker JE (2018) ATP synthase fromhas an elaborated canonical F-domain and conventional catalytic sites. Proc Natl Acad Sci U S A 115, 2102-2107
Lee JJ, Sanchez-Martinez A, Zarate AMartinez, Benincá C, Mayor U, Clague MJ & Whitworth AJ (2018) Basal mitophagy is widespread inbut minimally affected by loss of Pink1 or parkin. J Cell Biol
Duncan AL, Ruprecht JJ, Kunji ERS & Robinson AJ (2018) Cardiolipin dynamics and binding to conserved residues in the mitochondrial ADP/ATP carrier. Biochim Biophys Acta 1860, 1035-1045
Sharma S, Singh P, Fernandez-Vizarra E, Zeviani M, van der Knaap MS & Saran RKumar (2018) Cavitating Leukoencephalopathy With Posterior Predominance Caused by a Deletion in the APOPT1 Gene in an Indian Boy. J Child Neurol 33, 428-431
Rossman MJ, Santos-Parker JR, Steward CAC, Bispham NZ, Cuevas LM, Rosenberg HL, Woodward KA, Chonchol M, Gioscia-Ryan RA, Murphy MP & Seals DR (2018) Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults. Hypertension
Jalloh I, Helmy A, Howe D, Shannon RJ, Grice P, Mason A, Gallagher CN, Murphy MP, Pickard J, Menon D, Carpenter TAdrian, Hutchinson PJohn & Carpenter K (2018) A comparison of oxidative lactate metabolism in traumatically injured brain and control brain. J Neurotrauma
Varghese F, Blaza JN, J Y Jones A, Jarman OD & Hirst J (2018) Deleting the IF-likesubunit fromATP synthase is not sufficient to activate ATP hydrolysis. Open Biol 8
F Raymond L, Horvath R & Chinnery PF (2018) First-line genomic diagnosis of mitochondrial disorders. Nat Rev Genet 19, 399-400
Gallipoli P, Giotopoulos G, Tzelepis K, Costa ASH, Vohra S, Medina-Perez P, Basheer F, Marando L, Di Lisio L, Dias JML, Yun H, Sasca D, Horton SJ, Vassiliou G, Frezza C & Huntly BJP (2018) Glutaminolysis is a metabolic dependency in FLT3acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition. Blood
Secinaro MA, Fortner KA, Dienz O, Logan A, Murphy MP, Anathy V, Boyson JE & Budd RC (2018) Glycolysis promotes caspase-3 activation in lipid rafts in T cells. Cell Death Dis 9, 62
Kurauskas V, Hessel A, Ma P, Lunetti P, Weinhäupl K, Imbert L, Brutscher B, King MS, Sounier R, Dolce V, Kunji ERS, Capobianco L, Chipot C, Dehez F, Bersch B & Schanda P (2018) How Detergent Impacts Membrane Proteins: Atomic-Level Views of Mitochondrial Carriers in Dodecylphosphocholine. J Phys Chem Lett 9, 933-938
Pak O, Scheibe S, Esfandiary A, Gierhardt M, Sydykov A, Logan A, Fysikopoulos A, Veit F, Hecker M, Kroschel F, Quanz K, Erb A, Schäfer K, Fassbinder M, Alebrahimdehkordi N, Ghofrani HA, Schermuly RT, Brandes RP, Seeger W, Murphy MP, Weissmann N & Sommer N (2018) Impact of the mitochondria-targeted antioxidant MitoQ on hypoxia-induced pulmonary hypertension. Eur Respir J
Molina JR, Sun Y, Protopopova M, Gera S, Bandi M, Bristow C, McAfoos T, Morlacchi P, Ackroyd J, Agip A-NA, Al-Atrash G, Asara J, Bardenhagen J, Carrillo CC, Carroll C, Chang E, Ciurea S, Cross JB, Czako B, Deem A, Daver N, de Groot JFrederick, Dong J-W, Feng N, Gao G, Gay J, Do MGeck, Greer J, Giuliani V, Han J, Han L, Henry VK, Hirst J, Huang S, Jiang Y, Kang Z, Khor T, Konoplev S, Lin Y-H, Liu G, Lodi A, Lofton T, Ma H, Mahendra M, Matre P, Mullinax R, Peoples M, Petrocchi A, Rodriguez-Canale J, Serreli R, Shi T, Smith M, Tabe Y, Theroff J, Tiziani S, Xu Q, Zhang Q, Muller F, DePinho RA, Toniatti C, Draetta GF, Heffernan TP, Konopleva M, Jones P, M Di Francesco E & Marszalek JR (2018) An inhibitor of oxidative phosphorylation exploits cancer vulnerability. Nat Med
Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sévin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP & O'Neill LA (2018) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature 556, 113-117
Buffin S, Ikhelef N, Prudent J, Dubayle J, Nougarede N, Varenne M-P, Moste C & Legastelois I (2018) A latex agglutination assay to quantify the amount of hemagglutinin protein in adjuvanted low-dose influenza monovalent vaccines. J Virol Methods 251, 46-53
Sun Y, Zhang H, Xing X, Zhao Z, He J, Li J, Chen J, Wang M & He Y (2018) Lead promotes abnormal angiogenesis induced by CCM3 gene defects via mitochondrial pathway. J Dev Orig Health Dis 9, 182-190
Deepa SS, Pharaoh G, Kinter M, Diaz V, Fok WC, Riddle K, Pulliam D, Hill S, Fischer KE, Soto V, Georgescu C, Wren JD, Viscomi C, Richardson A & Van Remmen H (2018) Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice. Aging Cell, e12769
Peeva V, Blei D, Trombly G, Corsi S, Szukszto MJ, Rebelo-Guiomar P, Gammage PA, Kudin AP, Becker C, Altmüller J, Minczuk MA, Zsurka G & Kunz WS (2018) Linear mitochondrial DNA is rapidly degraded by components of the replication machinery. Nat Commun 9, 1727
Peruzzotti-Jametti L, Bernstock JD, Vicario N, Costa ASH, Kwok CKeong, Leonardi T, Booty LM, Bicci I, Balzarotti B, Volpe G, Mallucci G, Manferrari G, Donegà M, Iraci N, Braga A, Hallenbeck JM, Murphy MP, Edenhofer F, Frezza C & Pluchino S (2018) Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation. Cell Stem Cell 22, 355-368.e13
Zhang H, Burr SP & Chinnery PF (2018) The mitochondrial DNA genetic bottleneck: inheritance and beyond. Essays Biochem
Burr SP, Pezet M & Chinnery PF (2018) Mitochondrial DNA Heteroplasmy and Purifying Selection in the Mammalian Female Germ Line. Dev Growth Differ 60, 21-32
Lia D, Reyes A, Campos JTamara Ara, Piolot T, Baijer J, J Radicella P & Campalans A (2018) Mitochondrial maintenance under oxidative stress depends on mitochondrial but not nuclear α isoform of OGG1. J Cell Sci
Martin JL, Gruszczyk AV, Beach TE, Murphy MP & Saeb-Parsy K (2018) Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury. Pediatr Nephrol
Fazakerley DJ, Minard AY, Krycer JR, Thomas KC, Stöckli J, Harney DJ, Burchfield JG, Maghzal GJ, Caldwell ST, Hartley RC, Stocker R, Murphy MP & James DE (2018) Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation. J Biol Chem 293, 7315-7328

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