Publications

Found 20 results
Filters: Keyword is Enzyme Activation  [Clear All Filters]
2018
Agip A-NA, Blaza JN, Bridges HR, Viscomi C, Rawson S, Muench SP & Hirst J (2018) Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states. Nat Struct Mol Biol 25, 548-556
Gallipoli P, Giotopoulos G, Tzelepis K, Costa ASH, Vohra S, Medina-Perez P, Basheer F, Marando L, Di Lisio L, Dias JML, Yun H, Sasca D, Horton SJ, Vassiliou G, Frezza C & Huntly BJP (2018) Glutaminolysis is a metabolic dependency in FLT3 acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition. Blood 131, 1639-1653
2014
Chouchani ET, Methner C, Buonincontri G, Hu C-H, Logan A, Sawiak SJ, Murphy MP & Krieg T (2014) Complex I deficiency due to selective loss of Ndufs4 in the mouse heart results in severe hypertrophic cardiomyopathy. PLoS One 9, e94157
Cerutti R, Pirinen E, Lamperti C, Marchet S, Sauve AA, Li W, Leoni V, Schon EA, Dantzer F, Auwerx J, Viscomi C & Zeviani M (2014) NAD(+)-dependent activation of Sirt1 corrects the phenotype in a mouse model of mitochondrial disease. Cell Metab 19, 1042-9
2013
Invernizzi F, Tigano M, Dallabona C, Donnini C, Ferrero I, Cremonte M, Ghezzi D, Lamperti C & Zeviani M (2013) A homozygous mutation in LYRM7/MZM1L associated with early onset encephalopathy, lactic acidosis, and severe reduction of mitochondrial complex III activity. Hum Mutat 34, 1619-22
Narendra DP, Wang C, Youle RJ & Walker JE (2013) PINK1 rendered temperature sensitive by disease-associated and engineered mutations. Hum Mol Genet 22, 2572-89
J Y Jones A & Hirst J (2013) A spectrophotometric coupled enzyme assay to measure the activity of succinate dehydrogenase. Anal Biochem 442, 19-23
2012
Narendra D, Walker JE & Youle R (2012) Mitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism. Cold Spring Harb Perspect Biol 4
Lopez J, Hesling C, Prudent J, Popgeorgiev N, Gadet R, Mikaelian I, Rimokh R, Gillet G & Gonzalo P (2012) Src tyrosine kinase inhibits apoptosis through the Erk1/2- dependent degradation of the death accelerator Bik. Cell Death Differ 19, 1459-69
2009
Supinski GS, Murphy MP & Callahan LA (2009) MitoQ administration prevents endotoxin-induced cardiac dysfunction. Am J Physiol Regul Integr Comp Physiol 297, R1095-102
Ricart KC, Bolisetty S, Johnson MS, Perez J, Agarwal A, Murphy MP & Landar A (2009) The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cells. Biochem J 419, 427-36
2007
Floyd S, Favre C, Lasorsa FM, Leahy M, Trigiante G, Stroebel P, Marx A, Loughran G, O'Callaghan K, Marobbio CMT, Slotboom DJ, Kunji ERS, Palmieri F & O'Connor R (2007) The insulin-like growth factor-I-mTOR signaling pathway induces the mitochondrial pyrimidine nucleotide carrier to promote cell growth. Mol Biol Cell 18, 3545-55
2006
Watanabe N, Zmijewski JW, Takabe W, Umezu-Goto M, Le Goffe C, Sekine A, Landar A, Watanabe A, Aoki J, Arai H, Kodama T, Murphy MP, Kalyanaraman R, Darley-Usmar VM & Noguchi N (2006) Activation of mitogen-activated protein kinases by lysophosphatidylcholine-induced mitochondrial reactive oxygen species generation in endothelial cells. Am J Pathol 168, 1737-48
2005
Bianchi P, Pimentel DR, Murphy MP, Colucci WS & Parini A (2005) A new hypertrophic mechanism of serotonin in cardiac myocytes: receptor-independent ROS generation. FASEB J 19, 641-3
2004
Chen K, Thomas SR, Albano A, Murphy MP & Keaney JF (2004) Mitochondrial function is required for hydrogen peroxide-induced growth factor receptor transactivation and downstream signaling. J Biol Chem 279, 35079-86
2000
Kavanagh NI, Ainscow EK & Brand MD (2000) Calcium regulation of oxidative phosphorylation in rat skeletal muscle mitochondria. Biochim Biophys Acta 1457, 57-70
1979
Laget PP & Smith JB (1979) Inhibitory properties of endogenous subunit epsilon in the Escherichia coli F1 ATPase. Arch Biochem Biophys 197, 83-9