Publications

Found 53 results
Filters: Keyword is Crystallography, X-Ray  [Clear All Filters]
2016
McCorvie TJ, Kopec J, Pey AL, Fitzpatrick F, Patel D, Chalk R, Shrestha L & Yue WW (2016) Molecular basis of classic galactosemia from the structure of human galactose 1-phosphate uridylyltransferase. Hum Mol Genet 25, 2234-2244
2015
Amunts A, Fiedorczuk K, Truong TT, Chandler J, E Greenberg P & Ramakrishnan V (2015) Bactobolin A binds to a site on the 70S ribosome distinct from previously seen antibiotics. J Mol Biol 427, 753-5
Bason JV, Montgomery MG, Leslie AGW & Walker JE (2015) How release of phosphate from mammalian F1-ATPase generates a rotary substep. Proc Natl Acad Sci U S A 112, 6009-14
Shirakihara Y, Shiratori A, Tanikawa H, Nakasako M, Yoshida M & Suzuki T (2015) Structure of a thermophilic F1-ATPase inhibited by an ε-subunit: deeper insight into the ε-inhibition mechanism. FEBS J 282, 2895-913
Morales-Rios E, Montgomery MG, Leslie AGW & Walker JE (2015) Structure of ATP synthase from Paracoccus denitrificans determined by X-ray crystallography at 4.0 Å resolution. Proc Natl Acad Sci U S A 112, 13231-6
2014
Srinivasan V, Pierik AJ & Lill R (2014) Crystal structures of nucleotide-free and glutathione-bound mitochondrial ABC transporter Atm1. Science 343, 1137-40
Bason JV, Montgomery MG, Leslie AGW & Walker JE (2014) Pathway of binding of the intrinsically disordered mitochondrial inhibitor protein to F1-ATPase. Proc Natl Acad Sci U S A 111, 11305-10
Heikal A, Nakatani Y, Dunn E, Weimar MR, Day CL, Baker EN, J Lott S, Sazanov LA & Cook GM (2014) Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation. Mol Microbiol 91, 950-64
Xu Y, Tao Y, Cheung LS, Fan C, Chen L-Q, Xu S, Perry K, Frommer WB & Feng L (2014) Structures of bacterial homologues of SWEET transporters in two distinct conformations. Nature 515, 448-52
2013
Baradaran R, Berrisford JM, Minhas GS & Sazanov LA (2013) Crystal structure of the entire respiratory complex I. Nature 494, 443-8
Robinson GC, Bason JV, Montgomery MG, Fearnley IM, Mueller DM, Leslie AGW & Walker JE (2013) The structure of F₁-ATPase from Saccharomyces cerevisiae inhibited by its regulatory protein IF₁. Open Biol 3, 120164
Shintre CA, Pike ACW, Li Q, Kim J-I, Barr AJ, Goubin S, Shrestha L, Yang J, Berridge G, Ross J, Stansfeld PJ, Sansom MSP, Edwards AM, Bountra C, Marsden BD, von Delft F, Bullock AN, Gileadi O, Burgess-Brown NA & Carpenter EP (2013) Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states. Proc Natl Acad Sci U S A 110, 9710-5
2012
Kelso GF, Maroz A, Cochemé HM, Logan A, Prime TA, Peskin AV, Winterbourn CC, James AM, Ross MF, Brooker S, Porteous CM, Anderson RF, Murphy MP & Smith RAJ (2012) A mitochondria-targeted macrocyclic Mn(II) superoxide dismutase mimetic. Chem Biol 19, 1237-46
Rees DM, Montgomery MG, Leslie AGW & Walker JE (2012) Structural evidence of a new catalytic intermediate in the pathway of ATP hydrolysis by F1-ATPase from bovine heart mitochondria. Proc Natl Acad Sci U S A 109, 11139-43
2011
Cingolani G & Duncan TM (2011) Structure of the ATP synthase catalytic complex (F(1)) from Escherichia coli in an autoinhibited conformation. Nat Struct Mol Biol 18, 701-7
Efremov RG & Sazanov LA (2011) Structure of the membrane domain of respiratory complex I. Nature 476, 414-20
2010
Efremov RG, Baradaran R & Sazanov LA (2010) The architecture of respiratory complex I. Nature 465, 441-5
Kunji ERS & Crichton PG (2010) Mitochondrial carriers function as monomers. Biochim Biophys Acta 1797, 817-31
Requejo R, Chouchani ET, James AM, Prime TA, Lilley KS, Fearnley IM & Murphy MP (2010) Quantification and identification of mitochondrial proteins containing vicinal dithiols. Arch Biochem Biophys 504, 228-35
Zhou A, Carrell RW, Murphy MP, Wei Z, Yan Y, Stanley PLD, Stein PE, Pipkin FBroughton & Read RJ (2010) A redox switch in angiotensinogen modulates angiotensin release. Nature 468, 108-11
2009
Kabaleeswaran V, Shen H, Symersky J, Walker JE, Leslie AGW & Mueller DM (2009) Asymmetric structure of the yeast F1 ATPase in the absence of bound nucleotides. J Biol Chem 284, 10546-51
Berrisford JM & Sazanov LA (2009) Structural basis for the mechanism of respiratory complex I. J Biol Chem 284, 29773-83
2008
Murata T, Yamato I, Kakinuma Y, Shirouzu M, Walker JE, Yokoyama S & Iwata S (2008) Ion binding and selectivity of the rotor ring of the Na+-transporting V-ATPase. Proc Natl Acad Sci U S A 105, 8607-12
2007
Bowler MW, Montgomery MG, Leslie AGW & Walker JE (2007) Ground state structure of F1-ATPase from bovine heart mitochondria at 1.9 A resolution. J Biol Chem 282, 14238-42
Gledhill JR, Montgomery MG, Leslie AGW & Walker JE (2007) Mechanism of inhibition of bovine F₁-ATPase by resveratrol and related polyphenols. Proc Natl Acad Sci U S A 104, 13632-7

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