Publications

Found 66 results
Filters: Keyword is Protein Subunits  [Clear All Filters]
2016
Letts JA, Fiedorczuk K & Sazanov LA (2016) The architecture of respiratory supercomplexes. Nature 537, 644-648
Fiedorczuk K, Letts JA, Degliesposti G, Kaszuba K, Skehel M & Sazanov LA (2016) Atomic structure of the entire mammalian mitochondrial complex I. Nature 538, 406-410
Zhu J, Vinothkumar KR & Hirst J (2016) Structure of mammalian respiratory complex I. Nature 536, 354-8
2015
Walpole TB, Palmer DN, Jiang H, Ding S, Fearnley IM & Walker JE (2015) Conservation of complete trimethylation of lysine-43 in the rotor ring of c-subunits of metazoan adenosine triphosphate (ATP) synthases. Mol Cell Proteomics 14, 828-40
Allegretti M, Klusch N, Mills DJ, Vonck J, Kühlbrandt W & Davies KM (2015) Horizontal membrane-intrinsic α-helices in the stator a-subunit of an F-type ATP synthase. Nature 521, 237-40
Lee J, Ding S, Walpole TB, Holding AN, Montgomery MG, Fearnley IM & Walker JE (2015) Organization of Subunits in the Membrane Domain of the Bovine F-ATPase Revealed by Covalent Cross-linking. J Biol Chem 290, 13308-20
Liu S, Charlesworth TJ, Bason JV, Montgomery MG, Harbour ME, Fearnley IM & Walker JE (2015) The purification and characterization of ATP synthase complexes from the mitochondria of four fungal species. Biochem J 468, 167-75
Zhu J, King MS, Yu M, Klipcan L, Leslie AGW & Hirst J (2015) Structure of subcomplex Iβ of mammalian respiratory complex I leads to new supernumerary subunit assignments. Proc Natl Acad Sci U S A 112, 12087-92
2014
Vinothkumar KR, Zhu J & Hirst J (2014) Architecture of mammalian respiratory complex I. Nature 515, 80-4
Bason JV, Montgomery MG, Leslie AGW & Walker JE (2014) Pathway of binding of the intrinsically disordered mitochondrial inhibitor protein to F1-ATPase. Proc Natl Acad Sci U S A 111, 11305-10
Azarashvili T, Odinokova I, Bakunts A, Ternovsky V, Krestinina O, Tyynelä J & Saris N-ELeo (2014) Potential role of subunit c of F0F1-ATPase and subunit c of storage body in the mitochondrial permeability transition. Effect of the phosphorylation status of subunit c on pore opening. Cell Calcium 55, 69-77
Alavian KN, Beutner G, Lazrove E, Sacchetti S, Park H-A, Licznerski P, Li H, Nabili P, Hockensmith K, Graham M, Porter GA & Jonas EA (2014) An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore. Proc Natl Acad Sci U S A 111, 10580-5
2013
Runswick MJ, Bason JV, Montgomery MG, Robinson GC, Fearnley IM & Walker JE (2013) The affinity purification and characterization of ATP synthase complexes from mitochondria. Open Biol 3, 120160
Chouchani ET, Methner C, Nadtochiy SM, Logan A, Pell VR, Ding S, James AM, Cochemé HM, Reinhold J, Lilley KS, Partridge L, Fearnley IM, Robinson AJ, Hartley RC, Smith RAJ, Krieg T, Brookes PS & Murphy MP (2013) Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I. Nat Med 19, 753-9
Baradaran R, Berrisford JM, Minhas GS & Sazanov LA (2013) Crystal structure of the entire respiratory complex I. Nature 494, 443-8
Birrell JA, Morina K, Bridges HR, Friedrich T & Hirst J (2013) Investigating the function of [2Fe-2S] cluster N1a, the off-pathway cluster in complex I, by manipulating its reduction potential. Biochem J 456, 139-46
Sazanov LA, Baradaran R, Efremov RG, Berrisford JM & Minhas G (2013) A long road towards the structure of respiratory complex I, a giant molecular proton pump. Biochem Soc Trans 41, 1265-71
2012
Baker LA, Watt IN, Runswick MJ, Walker JE & Rubinstein JL (2012) Arrangement of subunits in intact mammalian mitochondrial ATP synthase determined by cryo-EM. Proc Natl Acad Sci U S A 109, 11675-80
Lamperti C, Diodato D, Lamantea E, Carrara F, Ghezzi D, Mereghetti P, Rizzi R & Zeviani M (2012) MELAS-like encephalomyopathy caused by a new pathogenic mutation in the mitochondrial DNA encoded cytochrome c oxidase subunit I. Neuromuscul Disord 22, 990-4
2011
Bason JV, Runswick MJ, Fearnley IM & Walker JE (2011) Binding of the inhibitor protein IF(1) to bovine F(1)-ATPase. J Mol Biol 406, 443-53
Lee S, Tak E, Lee J, Rashid MA, Murphy MP, Ha J & Kim SSoo (2011) Mitochondrial H2O2 generated from electron transport chain complex I stimulates muscle differentiation. Cell Res 21, 817-34
Bridges HR, Birrell JA & Hirst J (2011) The mitochondrial-encoded subunits of respiratory complex I (NADH:ubiquinone oxidoreductase): identifying residues important in mechanism and disease. Biochem Soc Trans 39, 799-806
Efremov RG & Sazanov LA (2011) Structure of the membrane domain of respiratory complex I. Nature 476, 414-20
Hirst J (2011) Why does mitochondrial complex I have so many subunits?. Biochem J 437, e1-3
2010
Efremov RG, Baradaran R & Sazanov LA (2010) The architecture of respiratory complex I. Nature 465, 441-5

Pages