Found 28 results
Filters: Keyword is Enzyme Inhibitors  [Clear All Filters]
Crichton PG, Lee Y, Ruprecht JJ, Cerson E, Thangaratnarajah C, King MS & Kunji ERS (2015) Trends in thermostability provide information on the nature of substrate, inhibitor, and lipid interactions with mitochondrial carriers. J Biol Chem 290, 8206-17
Pirinen E, Cantó C, Jo YSuk, Morato L, Zhang H, Menzies KJ, Williams EG, Mouchiroud L, Moullan N, Hagberg C, Li W, Timmers S, Imhof R, Verbeek J, Pujol A, van Loon B, Viscomi C, Zeviani M, Schrauwen P, Sauve AA, Schoonjans K & Auwerx J (2014) Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle. Cell Metab 19, 1034-41
Da-Rè C, De Pittà C, Zordan MA, Teza G, Nestola F, Zeviani M, Costa R & Bernardi P (2014) UCP4C mediates uncoupled respiration in larvae of Drosophila melanogaster. EMBO Rep 15, 586-91
Davies AL, Desai RA, Bloomfield PS, McIntosh PR, Chapple KJ, Linington C, Fairless R, Diem R, Kasti M, Murphy MP & Smith KJ (2013) Neurological deficits caused by tissue hypoxia in neuroinflammatory disease. Ann Neurol 74, 815-25
Lopez J, Hesling C, Prudent J, Popgeorgiev N, Gadet R, Mikaelian I, Rimokh R, Gillet G & Gonzalo P (2012) Src tyrosine kinase inhibits apoptosis through the Erk1/2- dependent degradation of the death accelerator Bik. Cell Death Differ 19, 1459-69
Morales-Rios E, de la Rosa-Morales F, Mendoza-Hernández G, Rodríguez-Zavala JS, Celis H, Zarco-Zavala M & García-Trejo JJ (2010) A novel 11-kDa inhibitory subunit in the F1FO ATP synthase of Paracoccus denitrificans and related alpha-proteobacteria. FASEB J 24, 599-608
Fernandez-Ayala DJM, Sanz A, Vartiainen S, Kemppainen KK, Babusiak M, Mustalahti E, Costa R, Tuomela T, Zeviani M, Chung J, O'Dell KMC, Rustin P & Jacobs HT (2009) Expression of the Ciona intestinalis alternative oxidase (AOX) in Drosophila complements defects in mitochondrial oxidative phosphorylation. Cell Metab 9, 449-60
Gledhill JR, Montgomery MG, Leslie AGW & Walker JE (2007) Mechanism of inhibition of bovine F₁-ATPase by resveratrol and related polyphenols. Proc Natl Acad Sci U S A 104, 13632-7
Gledhill JR & Walker JE (2006) Inhibitors of the catalytic domain of mitochondrial ATP synthase. Biochem Soc Trans 34, 989-92
Longley MJ, Clark S, Man CYu Wai, Hudson G, Durham SE, Taylor RW, Nightingale S, Turnbull DM, Copeland WC & Chinnery PF (2006) Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia. Am J Hum Genet 78, 1026-34
Helmerhorst EJ, Stan M, Murphy MP, Sherman F & Oppenheim FG (2005) The concomitant expression and availability of conventional and alternative, cyanide-insensitive, respiratory pathways in Candida albicans. Mitochondrion 5, 200-11
Kagawa R, Montgomery MG, Braig K, Leslie AGW & Walker JE (2004) The structure of bovine F1-ATPase inhibited by ADP and beryllium fluoride. EMBO J 23, 2734-44
Abramov AY & Duchen MR (2003) Actions of ionomycin, 4-BrA23187 and a novel electrogenic Ca2+ ionophore on mitochondria in intact cells. Cell Calcium 33, 101-12
Smith VR, Fearnley IM & Walker JE (2003) Altered chromatographic behaviour of mitochondrial ADP/ATP translocase induced by stabilization of the protein by binding of 6'-O-fluorescein-atractyloside. Biochem J 376, 757-63
Kunji ERS & Harding M (2003) Projection structure of the atractyloside-inhibited mitochondrial ADP/ATP carrier of Saccharomyces cerevisiae. J Biol Chem 278, 36985-8
Echtay KS, Esteves TC, Pakay JL, Jekabsons MB, Lambert AJ, Portero-Otín M, Pamplona R, Vidal-Puig AJ, Wang S, Roebuck SJ & Brand MD (2003) A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling. EMBO J 22, 4103-10
Pebay-Peyroula E, Dahout-Gonzalez C, Kahn R, Trézéguet V, Lauquin GJ-M & Brandolin G (2003) Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside. Nature 426, 39-44
St-Pierre J, Buckingham JA, Roebuck SJ & Brand MD (2002) Topology of superoxide production from different sites in the mitochondrial electron transport chain. J Biol Chem 277, 44784-90
Cabezón E, Arechaga I, Jonathan P, Butler G & Walker JE (2000) Dimerization of bovine F1-ATPase by binding the inhibitor protein, IF1. J Biol Chem 275, 28353-5
Krauss S & Brand MD (2000) Quantitation of signal transduction. FASEB J 14, 2581-8
Braig K, Menz RI, Montgomery MG, Leslie AG & Walker JE (2000) Structure of bovine mitochondrial F(1)-ATPase inhibited by Mg(2+) ADP and aluminium fluoride. Structure 8, 567-73
Luh FY, Archer SJ, Domaille PJ, Smith BO, Owen D, Brotherton DH, Raine AR, Xu X, Brizuela L, Brenner SL & Laue ED (1997) Structure of the cyclin-dependent kinase inhibitor p19Ink4d. Nature 389, 999-1003