Publications

Found 16 results
Filters: Keyword is Lipid Peroxidation  [Clear All Filters]
2015
Powell RD, Swet JH, Kennedy KL, Huynh TT, Murphy MP, Mckillop IH & Evans SL (2015) MitoQ modulates oxidative stress and decreases inflammation following hemorrhage. J Trauma Acute Care Surg 78, 573-9
2012
Prime TA, Forkink M, Logan A, Finichiu PG, McLachlan J, Pun PBoon Li, Koopman WJH, Larsen L, Latter MJ, Smith RAJ & Murphy MP (2012) A ratiometric fluorescent probe for assessing mitochondrial phospholipid peroxidation within living cells. Free Radic Biol Med 53, 544-53
Pung YFen, Rocic P, Murphy MP, Smith RAJ, Hafemeister J, Ohanyan V, Guarini G, Yin L & Chilian WM (2012) Resolution of mitochondrial oxidative stress rescues coronary collateral growth in Zucker obese fatty rats. Arterioscler Thromb Vasc Biol 32, 325-34
2010
Manczak M, Mao P, Calkins MJ, Cornea A, Reddy AP, Murphy MP, Szeto HH, Park B & P Reddy H (2010) Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons. J Alzheimers Dis 20 Suppl 2, S609-31
2009
Trnka J, Blaikie FH, Logan A, Smith RAJ & Murphy MP (2009) Antioxidant properties of MitoTEMPOL and its hydroxylamine. Free Radic Res 43, 4-12
Maroz A, Anderson RF, Smith RAJ & Murphy MP (2009) Reactivity of ubiquinone and ubiquinol with superoxide and the hydroperoxyl radical: implications for in vivo antioxidant activity. Free Radic Biol Med 46, 105-9
2006
Magwere T, Pamplona R, Miwa S, Martinez-Diaz P, Portero-Otín M, Brand MD & Partridge L (2006) Flight activity, mortality rates, and lipoxidative damage in Drosophila. J Gerontol A Biol Sci Med Sci 61, 136-45
Murphy MP (2006) Induction of mitochondrial ROS production by electrophilic lipids: a new pathway of redox signaling?. Am J Physiol Heart Circ Physiol 290, H1754-5
2005
Echtay KS, Pakay JL, Esteves TC & Brand MD (2005) Hydroxynonenal and uncoupling proteins: a model for protection against oxidative damage. Biofactors 24, 119-30
James AM, Cochemé HM, Smith RAJ & Murphy MP (2005) Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools. J Biol Chem 280, 21295-312
Kujoth GC, Hiona A, Pugh TD, Someya S, Panzer K, Wohlgemuth SE, Hofer T, Seo AY, Sullivan R, Jobling WA, Morrow JD, Van Remmen H, Sedivy JM, Yamasoba T, Tanokura M, Weindruch R, Leeuwenburgh C & Prolla TA (2005) Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 309, 481-4
2004
Brand MD, Affourtit C, Esteves TC, Green K, Lambert AJ, Miwa S, Pakay JL & Parker N (2004) Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins. Free Radic Biol Med 37, 755-67
2003
Murphy MP, Echtay KS, Blaikie FH, Asin-Cayuela J, Cochemé HM, Green K, Buckingham JA, Taylor ER, Hurrell F, Hughes G, Miwa S, Cooper CE, Svistunenko DA, Smith RAJ & Brand MD (2003) Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone. J Biol Chem 278, 48534-45