Publications

Found 28 results
Filters: Keyword is Adenosine Diphosphate  [Clear All Filters]
2018
Majd H, King MS, Palmer SM, Smith AC, Elbourne LDh, Paulsen IT, Sharples D, Henderson PJf & Kunji ERs (2018) Screening of candidate substrates and coupling ions of transporters by thermostability shift assays. Elife 7
2017
Springett R, King MS, Crichton PG & Kunji ERS (2017) Modelling the free energy profile of the mitochondrial ADP/ATP carrier. Biochim Biophys Acta 1858, 906-914
2016
Thompson K, Majd H, Dallabona C, Reinson K, King MS, Alston CL, He L, Lodi T, Jones SA, Fattal-Valevski A, Fraenkel ND, Saada A, Haham A, Isohanni P, Vara R, Barbosa IA, Simpson MA, Deshpande C, Puusepp S, Bonnen PE, Rodenburg RJ, Suomalainen A, Ounap K, Elpeleg O, Ferrero I, McFarland R, Kunji ERS & Taylor RW (2016) Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number. Am J Hum Genet 99, 860-876
Kunji ERS, Aleksandrova A, King MS, Majd H, Ashton VL, Cerson E, Springett R, Kibalchenko M, Tavoulari S, Crichton PG & Ruprecht JJ (2016) The transport mechanism of the mitochondrial ADP/ATP carrier. Biochim Biophys Acta 1863, 2379-93
2015
Bason JV, Montgomery MG, Leslie AGW & Walker JE (2015) How release of phosphate from mammalian F1-ATPase generates a rotary substep. Proc Natl Acad Sci U S A 112, 6009-14
2013
Birrell JA & Hirst J (2013) Investigation of NADH binding, hydride transfer, and NAD(+) dissociation during NADH oxidation by mitochondrial complex I using modified nicotinamide nucleotides. Biochemistry 52, 4048-55
Robinson GC, Bason JV, Montgomery MG, Fearnley IM, Mueller DM, Leslie AGW & Walker JE (2013) The structure of F₁-ATPase from Saccharomyces cerevisiae inhibited by its regulatory protein IF₁. Open Biol 3, 120164
Mifsud J, Ravaud S, Krammer E-M, Chipot C, Kunji ERS, Pebay-Peyroula E & Dehez F (2013) The substrate specificity of the human ADP/ATP carrier AAC1. Mol Membr Biol 30, 160-8
2012
Rees DM, Montgomery MG, Leslie AGW & Walker JE (2012) Structural evidence of a new catalytic intermediate in the pathway of ATP hydrolysis by F1-ATPase from bovine heart mitochondria. Proc Natl Acad Sci U S A 109, 11139-43
2010
Watt IN, Montgomery MG, Runswick MJ, Leslie AGW & Walker JE (2010) Bioenergetic cost of making an adenosine triphosphate molecule in animal mitochondria. Proc Natl Acad Sci U S A 107, 16823-7
2007
Bowler MW, Montgomery MG, Leslie AGW & Walker JE (2007) Ground state structure of F1-ATPase from bovine heart mitochondria at 1.9 A resolution. J Biol Chem 282, 14238-42
Feniouk BA, Suzuki T & Yoshida M (2007) Regulatory interplay between proton motive force, ADP, phosphate, and subunit epsilon in bacterial ATP synthase. J Biol Chem 282, 764-72
2006
Kabaleeswaran V, Puri N, Walker JE, Leslie AGW & Mueller DM (2006) Novel features of the rotary catalytic mechanism revealed in the structure of yeast F1 ATPase. EMBO J 25, 5433-42
Affourtit C & Brand MD (2006) Stronger control of ATP/ADP by proton leak in pancreatic beta-cells than skeletal muscle mitochondria. Biochem J 393, 151-9
2004
Kagawa R, Montgomery MG, Braig K, Leslie AGW & Walker JE (2004) The structure of bovine F1-ATPase inhibited by ADP and beryllium fluoride. EMBO J 23, 2734-44
2003
Smith VR, Fearnley IM & Walker JE (2003) Altered chromatographic behaviour of mitochondrial ADP/ATP translocase induced by stabilization of the protein by binding of 6'-O-fluorescein-atractyloside. Biochem J 376, 757-63
Martinez LO, Jacquet S, Esteve J-P, Rolland C, Cabezon E, Champagne E, Pineau T, Georgeaud V, Walker JE, Tercé F, Collet X, Perret B & Barbaras R (2003) Ectopic beta-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis. Nature 421, 75-9
Suzuki T, Murakami T, Iino R, Suzuki J, Ono S, Shirakihara Y & Yoshida M (2003) F0F1-ATPase/synthase is geared to the synthesis mode by conformational rearrangement of epsilon subunit in response to proton motive force and ADP/ATP balance. J Biol Chem 278, 46840-6
Pebay-Peyroula E, Dahout-Gonzalez C, Kahn R, Trézéguet V, Lauquin GJ-M & Brandolin G (2003) Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside. Nature 426, 39-44
2002
van der Giezen M, Slotboom DJan, Horner DS, Dyal PL, Harding M, Xue G-P, T Embley M & Kunji ERS (2002) Conserved properties of hydrogenosomal and mitochondrial ADP/ATP carriers: a common origin for both organelles. EMBO J 21, 572-9
2001
Hirono-Hara Y, Noji H, Nishiura M, Muneyuki E, Hara KY, Yasuda R, Kinosita K & Yoshida M (2001) Pause and rotation of F(1)-ATPase during catalysis. Proc Natl Acad Sci U S A 98, 13649-54
Menz RI, Leslie AG & Walker JE (2001) The structure and nucleotide occupancy of bovine mitochondrial F(1)-ATPase are not influenced by crystallisation at high concentrations of nucleotide. FEBS Lett 494, 11-4
Menz RI, Walker JE & Leslie AG (2001) Structure of bovine mitochondrial F(1)-ATPase with nucleotide bound to all three catalytic sites: implications for the mechanism of rotary catalysis. Cell 106, 331-41
2000
Braig K, Menz RI, Montgomery MG, Leslie AG & Walker JE (2000) Structure of bovine mitochondrial F(1)-ATPase inhibited by Mg(2+) ADP and aluminium fluoride. Structure 8, 567-73

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