Publications

Found 28 results
Filters: Keyword is Catalytic Domain  [Clear All Filters]
2016
Letts JA, Fiedorczuk K & Sazanov LA (2016) The architecture of respiratory supercomplexes. Nature 537, 644-648
McCorvie TJ, Kopec J, Pey AL, Fitzpatrick F, Patel D, Chalk R, Shrestha L & Yue WW (2016) Molecular basis of classic galactosemia from the structure of human galactose 1-phosphate uridylyltransferase. Hum Mol Genet 25, 2234-2244
2015
Bason JV, Montgomery MG, Leslie AGW & Walker JE (2015) How release of phosphate from mammalian F1-ATPase generates a rotary substep. Proc Natl Acad Sci U S A 112, 6009-14
Lee J, Ding S, Walpole TB, Holding AN, Montgomery MG, Fearnley IM & Walker JE (2015) Organization of Subunits in the Membrane Domain of the Bovine F-ATPase Revealed by Covalent Cross-linking. J Biol Chem 290, 13308-20
Shirakihara Y, Shiratori A, Tanikawa H, Nakasako M, Yoshida M & Suzuki T (2015) Structure of a thermophilic F1-ATPase inhibited by an ε-subunit: deeper insight into the ε-inhibition mechanism. FEBS J 282, 2895-913
2013
García-Gómez S, Reyes A, Martínez-Jiménez MI, E Chocrón S, Mourón S, Terrados G, Powell C, Salido E, Méndez J, Holt IJ & Blanco L (2013) PrimPol, an archaic primase/polymerase operating in human cells. Mol Cell 52, 541-53
Robinson GC, Bason JV, Montgomery MG, Fearnley IM, Mueller DM, Leslie AGW & Walker JE (2013) The structure of F₁-ATPase from Saccharomyces cerevisiae inhibited by its regulatory protein IF₁. Open Biol 3, 120164
2012
Bridges HR, Bill E & Hirst J (2012) Mössbauer spectroscopy on respiratory complex I: the iron-sulfur cluster ensemble in the NADH-reduced enzyme is partially oxidized. Biochemistry 51, 149-58
2011
Woodroof HI, Pogson JH, Begley M, Cantley LC, Deak M, Campbell DG, van Aalten DMF, Whitworth AJ, Alessi DR & Muqit MMK (2011) Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations. Open Biol 1, 110012
Yip C-ying, Harbour ME, Jayawardena K, Fearnley IM & Sazanov LA (2011) Evolution of respiratory complex I: "supernumerary" subunits are present in the alpha-proteobacterial enzyme. J Biol Chem 286, 5023-33
Armstrong FA & Hirst J (2011) Reversibility and efficiency in electrocatalytic energy conversion and lessons from enzymes. Proc Natl Acad Sci U S A 108, 14049-54
Minczuk MA, He J, Duch AM, Ettema TJ, Chlebowski A, Dzionek K, Nijtmans LGJ, Huynen MA & Holt IJ (2011) TEFM (c17orf42) is necessary for transcription of human mtDNA. Nucleic Acids Res 39, 4284-99
2010
Watt IN, Montgomery MG, Runswick MJ, Leslie AGW & Walker JE (2010) Bioenergetic cost of making an adenosine triphosphate molecule in animal mitochondria. Proc Natl Acad Sci U S A 107, 16823-7
Crichton PG, Albury MS, Affourtit C & Moore AL (2010) Mutagenesis of the Sauromatum guttatum alternative oxidase reveals features important for oxygen binding and catalysis. Biochim Biophys Acta 1797, 732-7
2008
Hurd TR, Requejo R, Filipovska A, Brown S, Prime TA, Robinson AJ, Fearnley IM & Murphy MP (2008) Complex I within oxidatively stressed bovine heart mitochondria is glutathionylated on Cys-531 and Cys-704 of the 75-kDa subunit: potential role of CYS residues in decreasing oxidative damage. J Biol Chem 283, 24801-15
2007
Bowler MW, Montgomery MG, Leslie AGW & Walker JE (2007) Ground state structure of F1-ATPase from bovine heart mitochondria at 1.9 A resolution. J Biol Chem 282, 14238-42
2006
Gledhill JR & Walker JE (2006) Inhibitors of the catalytic domain of mitochondrial ATP synthase. Biochem Soc Trans 34, 989-92
Longley MJ, Clark S, Man CYu Wai, Hudson G, Durham SE, Taylor RW, Nightingale S, Turnbull DM, Copeland WC & Chinnery PF (2006) Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia. Am J Hum Genet 78, 1026-34
Kabaleeswaran V, Puri N, Walker JE, Leslie AGW & Mueller DM (2006) Novel features of the rotary catalytic mechanism revealed in the structure of yeast F1 ATPase. EMBO J 25, 5433-42
Walker JE & Dickson VKane (2006) The peripheral stalk of the mitochondrial ATP synthase. Biochim Biophys Acta 1757, 286-96
2005
Hinchliffe P & Sazanov LA (2005) Organization of iron-sulfur clusters in respiratory complex I. Science 309, 771-4
2004
Kagawa R, Montgomery MG, Braig K, Leslie AGW & Walker JE (2004) The structure of bovine F1-ATPase inhibited by ADP and beryllium fluoride. EMBO J 23, 2734-44
Graziewicz MA, Longley MJ, Bienstock RJ, Zeviani M & Copeland WC (2004) Structure-function defects of human mitochondrial DNA polymerase in autosomal dominant progressive external ophthalmoplegia. Nat Struct Mol Biol 11, 770-6
2001
Yasuda R, Noji H, Yoshida M, Kinosita K & Itoh H (2001) Resolution of distinct rotational substeps by submillisecond kinetic analysis of F1-ATPase. Nature 410, 898-904
Menz RI, Leslie AG & Walker JE (2001) The structure and nucleotide occupancy of bovine mitochondrial F(1)-ATPase are not influenced by crystallisation at high concentrations of nucleotide. FEBS Lett 494, 11-4

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