Publications

Found 12 results
Filters: Keyword is DNA Damage  [Clear All Filters]
2013
Yu E, Calvert PA, Mercer JR, Harrison J, Baker L, Figg NL, Kumar S, Wang JC, Hurst LA, Obaid DR, Logan A, West NEJ, Clarke MCH, Vidal-Puig A, Murphy MP & Bennett MR (2013) Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with higher-risk plaques in humans. Circulation 128, 702-12
Kennedy SR, Salk JJ, Schmitt MW & Loeb LA (2013) Ultra-sensitive sequencing reveals an age-related increase in somatic mitochondrial mutations that are inconsistent with oxidative damage. PLoS Genet 9, e1003794
2011
Marthandan S, Murphy MP, Billett E & Barnett Y (2011) An investigation of the effects of MitoQ on human peripheral mononuclear cells. Free Radic Res 45, 351-8
2010
Mercer JR, Cheng K-K, Figg N, Gorenne I, Mahmoudi M, Griffin J, Vidal-Puig A, Logan A, Murphy MP & Bennett M (2010) DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome. Circ Res 107, 1021-31
2009
Joosen AMCP, Kuhnle GGC, Aspinall SM, Barrow TM, Lecommandeur E, Azqueta A, Collins AR & Bingham SA (2009) Effect of processed and red meat on endogenous nitrosation and DNA damage. Carcinogenesis 30, 1402-7
2008
Cochemé HM & Murphy MP (2008) Complex I is the major site of mitochondrial superoxide production by paraquat. J Biol Chem 283, 1786-98
Zeviani M (2008) OPA1 mutations and mitochondrial DNA damage: keeping the magic circle in shape. Brain 131, 314-7
2007
Lambert AJ & Brand MD (2007) Research on mitochondria and aging, 2006-2007. Aging Cell 6, 417-20
2006
Cross AJ, Greetham HL, Pollock JRA, Rowland IR & Bingham SA (2006) Variability in fecal water genotoxicity, determined using the Comet assay, is independent of endogenous N-nitroso compound formation attributed to red meat consumption. Environ Mol Mutagen 47, 179-84
2005
Kujoth GC, Hiona A, Pugh TD, Someya S, Panzer K, Wohlgemuth SE, Hofer T, Seo AY, Sullivan R, Jobling WA, Morrow JD, Van Remmen H, Sedivy JM, Yamasoba T, Tanokura M, Weindruch R, Leeuwenburgh C & Prolla TA (2005) Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 309, 481-4
2003
Saretzki G, Murphy MP & von Zglinicki T (2003) MitoQ counteracts telomere shortening and elongates lifespan of fibroblasts under mild oxidative stress. Aging Cell 2, 141-3
2002
Hughes R, Pollock JRA & Bingham S (2002) Effect of vegetables, tea, and soy on endogenous N-nitrosation, fecal ammonia, and fecal water genotoxicity during a high red meat diet in humans. Nutr Cancer 42, 70-7