Publications

Found 1969 results
2019
Parikh S, Karaa A, Goldstein A, Bertini ESilvio, Chinnery PF, Christodoulou J, Cohen BH, Davis RL, Falk MJ, Fratter C, Horvath R, Koenig MKay, Mancuso M, McCormack S, McCormick EM, McFarland R, Nesbitt V, Schiff M, Steele H, Stockler S, Sue C, Tarnopolsky M, Thorburn DR, Vockley J & Rahman S (2019) Diagnosis of 'possible' mitochondrial disease: an existential crisis. J Med Genet 56, 123-130
Ruprecht J & Kunji ERS (2019) Editorial overview: COSB Membranes. Curr Opin Struct Biol 57, vi-viii
Noli L, Khorsandi SE, Pyle A, Giritharan G, Fogarty N, Capalbo A, Devito L, Jovanovic VM, Khurana P, Rosa H, Kolundzic N, Cvoro A, Niakan KK, Malik A, Foulk R, Heaton N, Ardawi MSaleh, Chinnery PF, Ogilvie C, Khalaf Y & Ilic D (2019) Effects of Thyroid Hormone on Mitochondria and Metabolism of Human Preimplantation Embryos. Stem Cells
Hoitzing H, Gammage PA, Van Haute L, Minczuk M, Johnston IG & Jones NS (2019) Energetic costs of cellular and therapeutic control of stochastic mitochondrial DNA populations. PLoS Comput Biol 15, e1007023
Nieminuszczy J, Broderick R, Bellani MA, Smethurst E, Schwab RA, Cherdyntseva V, Evmorfopoulou T, Lin Y-L, Minczuk M, Pasero P, Gagos S, Seidman MM & Niedzwiedz W (2019) EXD2 Protects Stressed Replication Forks and Is Required for Cell Viability in the Absence of BRCA1/2. Mol Cell
Boreikaite V, Wicky BIM, Watt IN, Clarke J & Walker JE (2019) Extrinsic conditions influence the self-association and structure of IF, the regulatory protein of mitochondrial ATP synthase. Proc Natl Acad Sci U S A 116, 10354-10359
Guyatt AL, Brennan RR, Burrows K, Guthrie PAI, Ascione R, Ring SM, Gaunt TR, Pyle A, Cordell HJ, Lawlor DA, Chinnery PF, Hudson G & Rodriguez S (2019) A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts. Hum Genomics 13, 6
Wei W, Tuna S, Keogh MJ, Smith KR, Aitman TJ, Beales PL, Bennett DL, Gale DP, Bitner-Glindzicz MAK, Black GC, Brennan P, Elliott P, Flinter FA, R Floto A, Houlden H, Irving M, Koziell A, Maher ER, Markus HS, Morrell NW, Newman WG, Roberts I, Sayer JA, Smith KGC, Taylor JC, Watkins H, Webster AR, Wilkie AOM, Williamson C, Ashford S, Penkett CJ, Stirrups KE, Rendon A, Ouwehand WH, Bradley JR, F Raymond L, Caulfield M, Turro E & Chinnery PF (2019) Germline selection shapes human mitochondrial DNA diversity. Science 364
McGrath TM, Spreckley E, Rodriguez AFernandez, Viscomi C, Alamshah A, Akalestou E, Murphy KG & Jones NS (2019) The homeostatic dynamics of feeding behaviour identify novel mechanisms of anorectic agents. PLoS Biol 17, e3000482
Sommerville EW, Rosa IDalla, Rosenberg MM, Bruni F, Thompson K, Rocha M, Blakely EL, He L, Falkous G, Schaefer AM, Yu-Wai-Man P, Chinnery PF, Hedstrom L, Spinazzola A, Taylor RW & Gorman GS (2019) Identification of a novel heterozygous guanosine monophosphate reductase (GMPR) variant in a patient with a late-onset disorder of mitochondrial DNA maintenance. Clin Genet
Gómez-Cabañas L, López-Cotarelo P, Criado-García O, Murphy MP, Boya P & Rodríguez-Fernández JLuis (2019) Immunological Synapse Formation Induces Mitochondrial Clustering and Mitophagy in Dendritic Cells. The Journal of Immunology 202, 1715 - 1723
Mohanraj K, Wasilewski M, Benincá C, Cysewski D, Poznanski J, Sakowska P, Bugajska Z, Deckers M, Dennerlein S, Fernandez-Vizarra E, Rehling P, Dadlez M, Zeviani M & Chacinska A (2019) Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7. EMBO Mol Med 11
von Stockum S, Sanchez-Martinez A, Corrà S, Chakraborty J, Marchesan E, Locatello L, Da Re C, Cusumano P, Caicci F, Ferrari V, Costa R, Bubacco L, Rasotto MBerica, Szabó I, Whitworth AJ, Scorrano L & Ziviani E (2019) Inhibition of the deubiquitinase USP8 corrects a Drosophila PINK1 model of mitochondria dysfunction. Life Sci Alliance 2
Pinho BR, Duarte AI, Canas PM, Moreira PI, Murphy MP & Oliveira JMA (2019) The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice. Free Radic Biol Med
Brischigliaro M, Corrà S, Tregnago C, Fernandez-Vizarra E, Zeviani M, Costa R & De Pittà C (2019) Knockdown of APOPT1/COA8 Causes Cytochrome Oxidase Deficiency, Neuromuscular Impairment, and Reduced Resistance to Oxidative Stress in Drosophila melanogaster. Front Physiol 10, 1143
Peretti D, Kim SH, Tufi R & Lev S (2019) Lipid Transfer Proteins and Membrane Contact Sites in Human Cancer. Front Cell Dev Biol 7, 371
Małecki JM, Willemen HLDM, Pinto R, Y Y Ho A, Moen A, Kjønstad IF, Burgering BMT, Zwartkruis F, Eijkelkamp N & Falnes PØ (2019) Lysine methylation by the mitochondrial methyltransferase FAM173B optimizes the function of mitochondrial ATP synthase. J Biol Chem 294, 1128-1141
Galván-Peña S, Carroll RG, Newman C, Hinchy EC, Palsson-McDermott E, Robinson EK, Covarrubias S, Nadin A, James AM, Haneklaus M, Carpenter S, Kelly VP, Murphy MP, Modis LK & O'Neill LA (2019) Malonylation of GAPDH is an inflammatory signal in macrophages. Nat Commun 10, 338
Rebelo-Guiomar P, Powell CA, Van Haute L & Minczuk M (2019) The mammalian mitochondrial epitranscriptome. Biochim Biophys Acta Gene Regul Mech 1862, 429-446
Agip A-NA, Blaza JN, Fedor JG & Hirst J (2019) Mammalian Respiratory Complex I Through the Lens of Cryo-EM. Annu Rev Biophys 48, 165-184
Nissanka N, Minczuk M & Moraes CT (2019) Mechanisms of Mitochondrial DNA Deletion Formation. Trends Genet 35, 235-244
Bundgaard A, James AM, Gruszczyk AV, Martin J, Murphy MP & Fago A (2019) Metabolic adaptations during extreme anoxia in the turtle heart and their implications for ischemia-reperfusion injury. Sci Rep 9, 2850
Van Haute L, Hendrick AG, D'Souza AR, Powell CA, Rebelo-Guiomar P, Harbour ME, Ding S, Fearnley IM, Andrews B & Minczuk M (2019) METTL15 introduces N4-methylcytidine into human mitochondrial 12S rRNA and is required for mitoribosome biogenesis. Nucleic Acids Res 47
Indrieri A, Carrella S, Romano A, Spaziano A, Marrocco E, Fernandez-Vizarra E, Barbato S, Pizzo M, Ezhova Y, Golia FM, Ciampi L, Tammaro R, Henao-Mejia J, Williams A, Flavell RA, De Leonibus E, Zeviani M, Surace EM, Banfi S & Franco B (2019) miR-181a/b downregulation exerts a protective action on mitochondrial disease models. EMBO Mol Med 11
Gammage PA & Frezza C (2019) Mitochondrial DNA: the overlooked oncogenome?. BMC Biol 17, 53

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