Publications

Found 2065 results
2020
Russell DA, Bridges HR, Serreli R, Kidd SL, Mateu N, Osberger TJ, Sore HF, Hirst J & Spring DR (2020) Hydroxylated Rotenoids Selectively Inhibit the Proliferation of Prostate Cancer Cells. J Nat Prod
Stephenson ZA, Harvey RF, Pryde KR, Mistry S, Hardy RE, Serreli R, Chung I, Allen TEH, Stoneley M, MacFarlane M, Fischer PM, Hirst J, Kellam B & Willis AE (2020) Identification of a novel toxicophore in anti-cancer chemotherapeutics that targets mitochondrial respiratory complex I. eLife 9
Wei W & Chinnery PF (2020) Inheritance of mitochondrial DNA in humans: implications for rare and common diseases. J Intern Med
Teulings NEWD, Garrud TAC, Niu Y, Skeffington KL, Beck C, Itani N, Conlon FG, Botting KJ, Nicholas LM, Ashmore TJ, Blackmore HL, Tong W, Camm EJ, Derks JB, Logan A, Murphy MP, Ozanne SE & Giussani DA (2020) Isolating adverse effects of glucocorticoids on the embryonic cardiovascular system. FASEB J
Gutiérrez-Fernández J, Kaszuba K, Minhas GS, Baradaran R, Tambalo M, Gallagher DT & Sazanov LA (2020) Key role of quinone in the mechanism of respiratory complex I. Nature Communications 11
Pérez MJosé, Ivanyuk D, Panagiotakopoulou V, Di Napoli G, Kalb S, Brunetti D, Al-Shaana R, Kaeser SA, Fraschka SAnne-Krist, Jucker M, Zeviani M, Viscomi C & Deleidi M (2020) Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids. Mol Psychiatry
Jing C, Castro-Dopico T, Richoz N, Tuong ZK, Ferdinand JR, Lok LSC, Loudon KW, Banham GD, Mathews RJ, Cader Z, Fitzpatrick S, Bashant KR, Kaplan MJ, Kaser A, Johnson RS, Murphy MP, Siegel RM & Clatworthy MR (2020) Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis. Proceedings of the National Academy of Sciences 117, 15160 - 15171
Bacman SR, Gammage PA, Minczuk M & Moraes CT (2020) Manipulation of mitochondrial genes and mtDNA heteroplasmy. Methods Cell Biol 155, 441-487
Prag HA, Gruszczyk AV, Huang MM, Beach TE, Young T, Tronci L, Nikitopoulou E, Mulvey JF, Ascione R, Hadjihambi A, Shattock MJ, Pellerin L, Saeb-Parsy K, Frezza C, James AM, Krieg T, Murphy MP & Aksentijević D (2020) Mechanism of succinate efflux upon reperfusion of the ischemic heart. Cardiovasc Res
Steele H, Gomez‐Duran A, Pyle A, Hopton S, Newman J, Stefanetti RJ, Charman SJ, Parikh JD, He L, Viscomi C, Jakovljevic DG, Hollingsworth KG, Robinson AJ, Taylor RW, Bottolo L, Horvath R & Chinnery PF (2020) Metabolic effects of bezafibrate in mitochondrial disease. EMBO Molecular Medicine 12
Kunji ERS & Ruprecht JJ (2020) The mitochondrial ADP/ATP carrier exists and functions as a monomer. Biochem Soc Trans 48, 1419-1432
Grba DN & Hirst J (2020) Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation. Nat Struct Mol Biol
Schon KR, Ratnaike T, van den Ameele J, Horvath R & Chinnery PF (2020) Mitochondrial Diseases: A Diagnostic Revolution. Trends Genet
Chowdhury ARoy, Zielonka J, Kalyanaraman B, Hartley RC, Murphy MP & Avadhani NG (2020) Mitochondria-targeted paraquat and metformin mediate ROS production to induce multiple pathways of retrograde signaling: A dose-dependent phenomenon. Redox Biology 36, 101606
Benincá C, Zanette V, Brischigliaro M, Johnson M, Reyes A, Valle DAlmeida do, Robinson AJ, Degiorgi A, Yeates A, Telles BAugusto, Prudent J, Baruffini E, Santos MLucia SF, de Souza RLehtonen R, Fernandez-Vizarra E, Whitworth AJ & Zeviani M (2020) Mutation in the MICOS subunit gene (MIC26) associated with an X-linked recessive mitochondrial myopathy, lactic acidosis, cognitive impairment and autistic features. J Med Genet
Charif M, Chevrollier A, Gueguen N, Bris C, Goudenège D, Desquiret-Dumas V, Leruez S, Colin E, Meunier A, Vignal C, Smirnov V, Defoort-Dhellemmes S, Bouvet IDrumare, Goizet C, Votruba M, Jurkute N, Yu-Wai-Man P, Tagliavini F, Caporali L, La Morgia C, Carelli V, Procaccio V, Zanlonghi X, Meunier I, Reynier P, Bonneau D, Amati-Bonneau P & Lenaers G (2020) Mutations in the m-AAA proteases AFG3L2 and SPG7 are causing isolated dominant optic atrophy. Neurol Genet 6, e428
Kurzawa-Akanbi M, Keogh M, Tsefou E, Ramsay L, Johnson M, Keers S, Ochieng LWsa, McNair A, Singh P, Khan A, Pyle A, Hudson G, Ince PG, Attems J, Burn J, Chinnery PF & Morris CM (2020) Neuropathological and biochemical investigation of Hereditary Ferritinopathycases with ferritin light chain mutation: Prominent protein aggregation in the absence of major mitochondrial or oxidative stress. Neuropathol Appl Neurobiol
Wei W, Pagnamenta AT, Gleadall N, Sanchis-Juan A, Stephens J, Broxholme J, Tuna S, Odhams CA, Fratter C, Turro E, Caulfield MJ, Taylor JC, Rahman S & Chinnery PF (2020) Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans. Nature Communications 11
Luna-Sanchez M, Benincá C, Cerutti R, Brea-Calvo G, Yeates A, Scorrano L, Zeviani M & Viscomi C (2020) Opa1 Overexpression Protects from Early-Onset Mpv17-Related Mouse Kidney Disease. Mol Ther
Coppa A, Guha S, Fourcade S, Parameswaran J, Ruiz M, Moser AB, Schlüter A, Murphy MP, Lizcano JMiguel, Miranda-Vizuete A, Dalfó E & Pujol A (2020) The peroxisomal fatty acid transporter ABCD1/PMP-4 is required in the C. elegans hypodermis for axonal maintenance: A worm model for adrenoleukodystrophy. Free Radic Biol Med
Olesen MA, Torres AK, Jara C, Murphy MP & Tapia-Rojas C (2020) Premature synaptic mitochondrial dysfunction in the hippocampus during aging contributes to memory loss. Redox Biology 34, 101558
Reyes A, Favia P, Vidoni S, Petruzzella V & Zeviani M (2020) RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases. PLoS Genet 16, e1008923
Sies H & Jones DP (2020) Reactive oxygen species (ROS) as pleiotropic physiological signalling agents. Nat Rev Mol Cell Biol
Strakova A, Nicholls TJ, Baez-Ortega A, Leathlobhair MNí, Sampson AT, Hughes K, Bolton IAG, Gori K, Wang J, Airikkala-Otter I, Allen JL, Allum KM, Arnold CL, Bansse-Issa L, Bhutia TN, Bisson JL, Blank K, Briceño C, Domracheva ACastillo, Corrigan AM, Cran HR, Crawford JT, Cutter SM, Davis E, de Castro KF, De Nardi AB, de Vos AP, Keenan LDelgadillo, Donelan EM, Huerta AREspinoza, Faramade IA, Fazil M, Fotopoulou E, Fruean SN, Gallardo-Arrieta F, Glebova O, Gouletsou PG, Manrique RFHäfelin, Henriques JJGP, Horta RS, Ignatenko N, Kane Y, King C, Koenig D, Krupa A, Kruzeniski SJ, Lanza-Perea M, Lazyan M, Quintana AMLopez, Losfelt T, Marino G, Castañeda SMartínez, Martínez-López MF, Masuruli BM, Meyer M, Migneco EJ, Nakanwagi B, Neal KB, Neunzig W, Nixon SJ, Ortega-Pacheco A, Pedraza-Ordoñez F, Peleteiro MC, Polak K, Pye RJ, Ramirez-Ante JC, Reece JF, Gutierrez JRojas, Sadia H, Schmeling SK, Shamanova O, Sherlock AG, Steenland-Smit AE, Svitich A, Martínez LJTapia, Ngoka IThoya, Torres CG, Tudor EM, van der Wel MG, Vițălaru BA, Vural SA, Walkinton O, Wehrle-Martinez AS, Widdowson SAE, Zvarich I, Chinnery PF, Falkenberg M, Gustafsson CM & Murchison EP (2020) Recurrent horizontal transfer identifies mitochondrial positive selection in a transmissible cancer. Nat Commun 11, 3059
Walker JE, Carroll J & He J (2020) Reply to Bernardi: The mitochondrial permeability transition pore and the ATP synthase. Proc Natl Acad Sci U S A

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