Publications

Found 1929 results
2019
Kanagasundaram NS, Baudouin SV, Rowling S, Prabhu M, Dark JH, Goodship THJ, Chinnery PF & Hudson G (2019) Mitochondrial Haplogroup and the Risk of Acute Kidney Injury Following Cardiac Bypass Surgery. Sci Rep 9, 2279
Patel R, Coulter LLee, Rimmer J, Parkes M, Chinnery PFrancis & Swift O (2019) Mitochondrial neurogastrointestinal encephalopathy: a clinicopathological mimic of Crohn's disease. BMC Gastroenterol 19, 11
Pinho BR, Reis SD, Hartley RC, Murphy MP & Oliveira JMA (2019) Mitochondrial superoxide generation induces a parkinsonian phenotype in zebrafish and huntingtin aggregation in human cells. Free Radic Biol Med 130, 318-327
Andreazza S, Samstag CL, Sanchez-Martinez A, Fernandez-Vizarra E, Gomez-Duran A, Lee JJ, Tufi R, Hipp MJ, Schmidt EK, Nicholls TJ, Gammage PA, Chinnery PF, Minczuk M, Pallanck LJ, Kennedy SR & Whitworth AJ (2019) Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila. 10, 3280
Escribano-Lopez I, Bañuls C, Diaz-Morales N, Iannantuoni F, Rovira-Llopis S, Gomis R, Rocha M, Hernandez-Mijares A, Murphy MP & Víctor VM (2019) The Mitochondria-Targeted Antioxidant MitoQ Modulates Mitochondrial Function and Endoplasmic Reticulum Stress in Pancreatic β Cells Exposed to Hyperglycaemia. Cell Physiol Biochem 52, 186-197
Smith AC & Robinson AJ (2019) MitoMiner v4.0: an updated database of mitochondrial localization evidence, phenotypes and diseases. Nucleic Acids Res 47, D1225-D1228
Ruprecht JJ, King MS, Zögg T, Aleksandrova AA, Pardon E, Crichton PG, Steyaert J & Kunji ERS (2019) The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier. Cell 176, 435-447.e15
Ugun-Klusek A, Theodosi TS, Fitzgerald JC, Burté F, Ufer C, Boocock DJ, Yu-Wai-Man P, Bedford L & E Billett E (2019) Monoamine oxidase-A promotes protective autophagy in human SH-SY5Y neuroblastoma cells through Bcl-2 phosphorylation. Redox Biol 20, 167-181
Saoura M, Powell CA, Kopajtich R, Alahmad A, Al-Balool HH, Albash B, Alfadhel M, Alston CL, Bertini E, Bonnen PE, Bratkovic D, Carrozzo R, Donati MA, Di Nottia M, Ghezzi D, Goldstein A, Haan E, Horvath R, Hughes J, Invernizzi F, Lamantea E, Lucas B, Pinnock K-G, Pujantell M, Rahman S, Rebelo-Guiomar P, Santra S, Verrigni D, McFarland R, Prokisch H, Taylor RW, Levinger L & Minczuk M (2019) Mutations in ELAC2 associated with hypertrophic cardiomyopathy impair mitochondrial tRNA 3'-end processing. Hum Mutat
van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernández I, van Eijk KR, Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleó A, Zetterberg H, Nygaard M, Blauwendraat C, Savage JE, Mengel-From J, Moreno-Grau S, Wagner M, Fortea J, Keogh MJ, Blennow K, Skoog I, Friese MA, Pletnikova O, Zulaica M, Lage C, de Rojas I, Riedel-Heller S, Illán-Gala I, Wei W, Jeune B, Orellana A, Bergh FThen, Wang X, Hulsman M, Beker N, Tesi N, Morris CM, Indakoetxea B, Collij LE, Scherer M, Morenas-Rodríguez E, Ironside JW, van Berckel BNM, Alcolea D, Wiendl H, Strickland SL, Pastor P, Rodríguez ERodríguez, Boeve BF, Petersen RC, Ferman TJ, van Gerpen JA, Reinders MJT, Uitti RJ, Tárraga L, Maier W, Dols-Icardo O, Kawalia A, Dalmasso MCarolina, Boada M, Zettl UK, van Schoor NM, Beekman M, Allen M, Masliah E, de Munain ALópez, Pantelyat A, Wszolek ZK, Ross OA, Dickson DW, Graff-Radford NR, Knopman D, Rademakers R, Lemstra AW, Pijnenburg YAL, Scheltens P, Gasser T, Chinnery PF, Hemmer B, Huisman MA, Troncoso J, Moreno F, Nohr EA, Sørensen TIA, Heutink P, Sánchez-Juan P, Posthuma D, Clarimón J, Christensen K, Ertekin-Taner N, Scholz SW, Ramirez A, Ruiz A, Slagboom E, van der Flier WM & Holstege H (2019) A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta Neuropathol
Lim PJin, Duarte TL, Arezes J, Garcia-Santos D, Hamdi A, Pasricha S-R, Armitage AE, Mehta H, Wideman S, Santos AG, Santos-Gonçalves A, Morovat A, Hughes JR, Soilleux E, Wang C-Y, Bayer AL, Klenerman P, Willberg CB, Hartley RC, Murphy MP, Babitt JL, Ponka P, Porto G & Drakesmith H (2019) Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin. Nat Metab 1, 519-531
Ng YShiau, Martikainen MH, Gorman GS, Blain A, Bugiardini E, Bunting A, Schaefer AM, Alston CL, Blakely EL, Sharma S, Hughes I, Lim A, de Goede C, McEntagart M, Spinty S, Horrocks I, Roberts M, Woodward CE, Chinnery PF, Horvath R, Nesbitt V, Fratter C, Poulton J, Hanna MG, Pitceathly RDS, Taylor RW, Turnbull DM & McFarland R (2019) Pathogenic variants in MT-ATP6: A United Kingdom-based mitochondrial disease cohort study. Ann Neurol
Carroll J, He J, Ding S, Fearnley IM & Walker JE (2019) Persistence of the permeability transition pore in human mitochondria devoid of an assembled ATP synthase. Proc Natl Acad Sci U S A 116, 12816-12821
Murphy MP (2019) Rerouting metabolism to activate macrophages. Nat Immunol
Posse V, Al-Behadili A, Uhler JP, Clausen AR, Reyes A, Zeviani M, Falkenberg M & Gustafsson CM (2019) RNase H1 directs origin-specific initiation of DNA replication in human mitochondria. PLoS Genet 15, e1007781
Murphy BJ, Klusch N, Langer J, Mills DJ, Yildiz Ö & Kühlbrandt W (2019) Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F-F coupling. Science 364
Booty LM, Gawel JM, Cvetko F, Caldwell ST, Hall AR, Mulvey JF, James AM, Hinchy EC, Prime TA, Arndt S, Benincá C, Bright TP, Clatworthy MR, Ferdinand JR, Prag HA, Logan A, Prudent J, Krieg T, Hartley RC & Murphy MP (2019) Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo. Cell Chem Biol 26, 449-461.e8
Jurkute N, Leu C, Pogoda H-M, Arno G, Robson AG, Nürnberg G, Altmüller J, Thiele H, Motameny S, Toliat MReza, Powell K, Höhne W, Michaelides M, Webster AR, Moore AT, Hammerschmidt M, Nürnberg P, Yu-Wai-Man P & Votruba M (2019) SSBP1 mutations in dominant optic atrophy with variable retinal degeneration. Ann Neurol
Ruprecht JJ & Kunji ERs (2019) Structural changes in the transport cycle of the mitochondrial ADP/ATP carrier. Curr Opin Struct Biol 57, 135-144
Guo H, Suzuki T & Rubinstein JL (2019) Structure of a bacterial ATP synthase. Elife 8
Petri J, Nakatani Y, Montgomery MG, Ferguson SA, Aragão D, Leslie AGW, Heikal A, Walker JE & Cook GM (2019) Structure of F-ATPase from the obligate anaerobe Fusobacterium nucleatum. Open Biol 9, 190066
Park J, Lee S-Y, Jeong H, Kang M-G, Van Haute L, Minczuk M, Seo JKon, Jun Y, Myung K, Rhee H-W & Lee C (2019) The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res
Zhang AT, Montgomery MG, Leslie AGW, Cook GM & Walker JE (2019) The structure of the catalytic domain of the ATP synthase from is a target for developing antitubercular drugs. Proc Natl Acad Sci U S A
Kim Y-R, Baek J-I, Kim SHwan, Kim M-A, Lee B, Ryu N, Kim K-H, Choi D-G, Kim H-M, Murphy MP, Macpherson G, Choo Y-S, Bok J, Lee K-Y, Park J-W & Kim U-K (2019) Therapeutic potential of the mitochondria-targeted antioxidant MitoQ in mitochondrial-ROS induced sensorineural hearing loss caused by Idh2 deficiency. Redox Biol 20, 544-555
Jurkute N, Harvey J & Yu-Wai-Man P (2019) Treatment strategies for Leber hereditary optic neuropathy. Curr Opin Neurol 32, 99-104

Pages