Publications

Found 65 results
Filters: Keyword is Electron Transport  [Clear All Filters]
2008
Lambert AJ, Buckingham JA, Boysen HM & Brand MD (2008) Diphenyleneiodonium acutely inhibits reactive oxygen species production by mitochondrial complex I during reverse, but not forward electron transport. Biochim Biophys Acta 1777, 397-403
Hirst J, King MS & Pryde KR (2008) The production of reactive oxygen species by complex I. Biochem Soc Trans 36, 976-80
2007
Worrall JAR, Schlarb-Ridley BG, Reda T, Marcaida MJ, Moorlen RJ, Wastl J, Hirst J, Bendall DS, Luisi BF & Howe CJ (2007) Modulation of heme redox potential in the cytochrome c6 family. J Am Chem Soc 129, 9468-75
Sazanov LA (2007) Respiratory complex I: mechanistic and structural insights provided by the crystal structure of the hydrophilic domain. Biochemistry 46, 2275-88
2006
Iuso A, Scacco S, Piccoli C, Bellomo F, Petruzzella V, Trentadue R, Minuto M, Ripoli M, Capitanio N, Zeviani M & Papa S (2006) Dysfunctions of cellular oxidative metabolism in patients with mutations in the NDUFS1 and NDUFS4 genes of complex I. J Biol Chem 281, 10374-80
Hirst J (2006) Elucidating the mechanisms of coupled electron transfer and catalytic reactions by protein film voltammetry. Biochim Biophys Acta 1757, 225-39
Reda T & Hirst J (2006) Interpreting the catalytic voltammetry of an adsorbed enzyme by considering substrate mass transfer, enzyme turnover, and interfacial electron transport. J Phys Chem B 110, 1394-404
2005
Palmieri L, Alberio S, Pisano I, Lodi T, Meznaric-Petrusa M, Zidar J, Santoro A, Scarcia P, Fontanesi F, Lamantea E, Ferrero I & Zeviani M (2005) Complete loss-of-function of the heart/muscle-specific adenine nucleotide translocator is associated with mitochondrial myopathy and cardiomyopathy. Hum Mol Genet 14, 3079-88
Helmerhorst EJ, Stan M, Murphy MP, Sherman F & Oppenheim FG (2005) The concomitant expression and availability of conventional and alternative, cyanide-insensitive, respiratory pathways in Candida albicans. Mitochondrion 5, 200-11
Koopman WJH, Verkaart S, Visch H-J, van der Westhuizen FH, Murphy MP, van den Heuvel LWPJ, Smeitink JAM & Willems PHGM (2005) Inhibition of complex I of the electron transport chain causes O2-. -mediated mitochondrial outgrowth. Am J Physiol Cell Physiol 288, C1440-50
James AM, Cochemé HM, Smith RAJ & Murphy MP (2005) Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools. J Biol Chem 280, 21295-312
Hinchliffe P & Sazanov LA (2005) Organization of iron-sulfur clusters in respiratory complex I. Science 309, 771-4
2004
Lambert AJ & Brand MD (2004) Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I). J Biol Chem 279, 39414-20
King A, Gottlieb E, Brooks DG, Murphy MP & Dunaief JL (2004) Mitochondria-derived reactive oxygen species mediate blue light-induced death of retinal pigment epithelial cells. Photochem Photobiol 79, 470-5
Zeviani M & Di Donato S (2004) Mitochondrial disorders. Brain 127, 2153-72
Brand MD, Affourtit C, Esteves TC, Green K, Lambert AJ, Miwa S, Pakay JL & Parker N (2004) Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins. Free Radic Biol Med 37, 755-67
2003
Miwa S, St-Pierre J, Partridge L & Brand MD (2003) Superoxide and hydrogen peroxide production by Drosophila mitochondria. Free Radic Biol Med 35, 938-48
2002
Elliott SJ, Léger C, Pershad HR, Hirst J, Heffron K, Ginet N, Blasco F, Rothery RA, Weiner JH & Armstrong FA (2002) Detection and interpretation of redox potential optima in the catalytic activity of enzymes. Biochim Biophys Acta 1555, 54-9
Roussel D, Harding M, Runswick MJ, Walker JE & Brand MD (2002) Does any yeast mitochondrial carrier have a native uncoupling protein function?. J Bioenerg Biomembr 34, 165-76
Corona P, Lamantea E, Greco M, Carrara F, Agostino A, Guidetti D, Dotti MT, Mariotti C & Zeviani M (2002) Novel heteroplasmic mtDNA mutation in a family with heterogeneous clinical presentations. Ann Neurol 51, 118-22
Lamantea E, Carrara F, Mariotti C, Morandi L, Tiranti V & Zeviani M (2002) A novel nonsense mutation (Q352X) in the mitochondrial cytochrome b gene associated with a combined deficiency of complexes I and III. Neuromuscul Disord 12, 49-52
Kelso GF, Porteous CM, Hughes G, Ledgerwood EC, Gane AM, Smith RAJ & Murphy MP (2002) Prevention of mitochondrial oxidative damage using targeted antioxidants. Ann N Y Acad Sci 959, 263-74

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