Publications

Found 57 results
Filters: Keyword is Signal Transduction  [Clear All Filters]
2012
Rorbach J & Minczuk M (2012) The post-transcriptional life of mammalian mitochondrial RNA. Biochem J 444, 357-73
2011
Barbolina MV, Burkhalter RJ & M Stack S (2011) Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment. Biochem J 437, 1-12
Whitworth AJ (2011) Drosophila models of Parkinson's disease. Adv Genet 73, 1-50
Viscomi C, Bottani E, Civiletto G, Cerutti R, Moggio M, Fagiolari G, Schon EA, Lamperti C & Zeviani M (2011) In vivo correction of COX deficiency by activation of the AMPK/PGC-1α axis. Cell Metab 14, 80-90
Murphy MP, Holmgren A, Larsson N-G, Halliwell B, Chang CJ, Kalyanaraman B, Rhee SGoo, Thornalley PJ, Partridge L, Gems D, Nyström T, Belousov V, Schumacker PT & Winterbourn CC (2011) Unraveling the biological roles of reactive oxygen species. Cell Metab 13, 361-366
2010
Requejo R, Chouchani ET, Hurd TR, Menger KE, Hampton MB & Murphy MP (2010) Measuring mitochondrial protein thiol redox state. Methods Enzymol 474, 123-47
2008
Harper M-E, Green K & Brand MD (2008) The efficiency of cellular energy transduction and its implications for obesity. Annu Rev Nutr 28, 13-33
Murphy MP & Partridge L (2008) Toward a control theory analysis of aging. Annu Rev Biochem 77, 777-98
2007
Echtay KS & Brand MD (2007) 4-hydroxy-2-nonenal and uncoupling proteins: an approach for regulation of mitochondrial ROS production. Redox Rep 12, 26-9
Hurd TR, Prime TA, Harbour ME, Lilley KS & Murphy MP (2007) Detection of reactive oxygen species-sensitive thiol proteins by redox difference gel electrophoresis: implications for mitochondrial redox signaling. J Biol Chem 282, 22040-51
Floyd S, Favre C, Lasorsa FM, Leahy M, Trigiante G, Stroebel P, Marx A, Loughran G, O'Callaghan K, Marobbio CMT, Slotboom DJ, Kunji ERS, Palmieri F & O'Connor R (2007) The insulin-like growth factor-I-mTOR signaling pathway induces the mitochondrial pyrimidine nucleotide carrier to promote cell growth. Mol Biol Cell 18, 3545-55
Bell EL, Klimova TA, Eisenbart J, Moraes CT, Murphy MP, Budinger GRScott & Chandel NS (2007) The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production. J Cell Biol 177, 1029-36
2006
Watanabe N, Zmijewski JW, Takabe W, Umezu-Goto M, Le Goffe C, Sekine A, Landar A, Watanabe A, Aoki J, Arai H, Kodama T, Murphy MP, Kalyanaraman R, Darley-Usmar VM & Noguchi N (2006) Activation of mitogen-activated protein kinases by lysophosphatidylcholine-induced mitochondrial reactive oxygen species generation in endothelial cells. Am J Pathol 168, 1737-48
O Pletjushkina Y, Fetisova EK, Lyamzaev KG, O Ivanova Y, Domnina LV, M Vyssokikh Y, Pustovidko AV, Alexeevski AV, Alexeevski DA, Vasiliev JM, Murphy MP, Chernyak BV & Skulachev VP (2006) Hydrogen peroxide produced inside mitochondria takes part in cell-to-cell transmission of apoptotic signal. Biochemistry (Mosc) 71, 60-7
Murphy MP (2006) Induction of mitochondrial ROS production by electrophilic lipids: a new pathway of redox signaling?. Am J Physiol Heart Circ Physiol 290, H1754-5
M Camello-Almaraz C, Pozo MJ, Murphy MP & Camello PJ (2006) Mitochondrial production of oxidants is necessary for physiological calcium oscillations. J Cell Physiol 206, 487-94
2005
Park D, Lee S, Bolser D, Schroeder M, Lappe M, Oh D & Bhak J (2005) Comparative interactomics analysis of protein family interaction networks using PSIMAP (protein structural interactome map). Bioinformatics 21, 3234-40
Spinazzola A & Zeviani M (2005) Disorders of nuclear-mitochondrial intergenomic signaling. Gene 354, 162-8
Hurd TR, Filipovska A, Costa NJ, Dahm CC & Murphy MP (2005) Disulphide formation on mitochondrial protein thiols. Biochem Soc Trans 33, 1390-3
James AM, Cochemé HM, Smith RAJ & Murphy MP (2005) Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools. J Biol Chem 280, 21295-312
Hughes G, Murphy MP & Ledgerwood EC (2005) Mitochondrial reactive oxygen species regulate the temporal activation of nuclear factor kappaB to modulate tumour necrosis factor-induced apoptosis: evidence from mitochondria-targeted antioxidants. Biochem J 389, 83-9
Brunelle JK, Bell EL, Quesada NM, Vercauteren K, Tiranti V, Zeviani M, Scarpulla RC & Chandel NS (2005) Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation. Cell Metab 1, 409-14
2004
Chen K, Thomas SR, Albano A, Murphy MP & Keaney JF (2004) Mitochondrial function is required for hydrogen peroxide-induced growth factor receptor transactivation and downstream signaling. J Biol Chem 279, 35079-86
Brand MD, Affourtit C, Esteves TC, Green K, Lambert AJ, Miwa S, Pakay JL & Parker N (2004) Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins. Free Radic Biol Med 37, 755-67

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