Publications

Found 449 results
Filters: Keyword is Mitochondria  [Clear All Filters]
2005
Ross MF, Kelso GF, Blaikie FH, James AM, Cochemé HM, Filipovska A, Da Ros T, Hurd TR, Smith RAJ & Murphy MP (2005) Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology. Biochemistry (Mosc) 70, 222-30
O Pletjushkina Y, Fetisova EK, Lyamzaev KG, O Ivanova Y, Domnina LV, M Vyssokikh Y, Pustovidko AV, Vasiliev JM, Murphy MP, Chernyak BV & Skulachev VP (2005) Long-distance apoptotic killing of cells is mediated by hydrogen peroxide in a mitochondrial ROS-dependent fashion. Cell Death Differ 12, 1442-4
Hughes G, Murphy MP & Ledgerwood EC (2005) Mitochondrial reactive oxygen species regulate the temporal activation of nuclear factor kappaB to modulate tumour necrosis factor-induced apoptosis: evidence from mitochondria-targeted antioxidants. Biochem J 389, 83-9
Kim A, Murphy MP & Oberley TD (2005) Mitochondrial redox state regulates transcription of the nuclear-encoded mitochondrial protein manganese superoxide dismutase: a proposed adaptive response to mitochondrial redox imbalance. Free Radic Biol Med 38, 644-54
James AM, Cochemé HM & Murphy MP (2005) Mitochondria-targeted redox probes as tools in the study of oxidative damage and ageing. Mech Ageing Dev 126, 982-6
Bustos DM & Velours J (2005) The modification of the conserved GXXXG motif of the membrane-spanning segment of subunit g destabilizes the supramolecular species of yeast ATP synthase. J Biol Chem 280, 29004-10
Brunelle JK, Bell EL, Quesada NM, Vercauteren K, Tiranti V, Zeviani M, Scarpulla RC & Chandel NS (2005) Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation. Cell Metab 1, 409-14
Brand MD & Esteves TC (2005) Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3. Cell Metab 2, 85-93
Esteves TC & Brand MD (2005) The reactions catalysed by the mitochondrial uncoupling proteins UCP2 and UCP3. Biochim Biophys Acta 1709, 35-44
Dudkina NV, Heinemeyer J, Keegstra W, Boekema EJ & Braun H-P (2005) Structure of dimeric ATP synthase from mitochondria: an angular association of monomers induces the strong curvature of the inner membrane. FEBS Lett 579, 5769-72
Sanjuan-Pla A, Cervera AM, Apostolova N, Garcia-Bou R, Víctor VM, Murphy MP & McCreath KJ (2005) A targeted antioxidant reveals the importance of mitochondrial reactive oxygen species in the hypoxic signaling of HIF-1alpha. FEBS Lett 579, 2669-74
Adlam VJ, Harrison JC, Porteous CM, James AM, Smith RAJ, Murphy MP & Sammut IA (2005) Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury. FASEB J 19, 1088-95
Miwa S & Brand MD (2005) The topology of superoxide production by complex III and glycerol 3-phosphate dehydrogenase in Drosophila mitochondria. Biochim Biophys Acta 1709, 214-9
2004
James AM, Smith RAJ & Murphy MP (2004) Antioxidant and prooxidant properties of mitochondrial Coenzyme Q. Arch Biochem Biophys 423, 47-56
Ross MF & Murphy MP (2004) Cell-penetrating peptides are excluded from the mitochondrial matrix. Biochem Soc Trans 32, 1072-4
Ross MF, Filipovska A, Smith RAJ, Gait MJ & Murphy MP (2004) Cell-penetrating peptides do not cross mitochondrial membranes even when conjugated to a lipophilic cation: evidence against direct passage through phospholipid bilayers. Biochem J 383, 457-68
Asin-Cayuela J, Manas A-RB, James AM, Smith RAJ & Murphy MP (2004) Fine-tuning the hydrophobicity of a mitochondria-targeted antioxidant. FEBS Lett 571, 9-16
Fiermonte G, De Leonardis F, Todisco S, Palmieri L, Lasorsa FMassimo & Palmieri F (2004) Identification of the mitochondrial ATP-Mg/Pi transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution. J Biol Chem 279, 30722-30
Lambert AJ & Brand MD (2004) Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I). J Biol Chem 279, 39414-20
Murphy MP (2004) Investigating mitochondrial radical production using targeted probes. Biochem Soc Trans 32, 1011-4
Miwa S, Riyahi K, Partridge L & Brand MD (2004) Lack of correlation between mitochondrial reactive oxygen species production and life span in Drosophila. Ann N Y Acad Sci 1019, 388-91
Chen R, Fearnley IM, Palmer DN & Walker JE (2004) Lysine 43 is trimethylated in subunit C from bovine mitochondrial ATP synthase and in storage bodies associated with batten disease. J Biol Chem 279, 21883-7
King A, Gottlieb E, Brooks DG, Murphy MP & Dunaief JL (2004) Mitochondria-derived reactive oxygen species mediate blue light-induced death of retinal pigment epithelial cells. Photochem Photobiol 79, 470-5
Chen K, Thomas SR, Albano A, Murphy MP & Keaney JF (2004) Mitochondrial function is required for hydrogen peroxide-induced growth factor receptor transactivation and downstream signaling. J Biol Chem 279, 35079-86
Brand MD, Buckingham JA, Esteves TC, Green K, Lambert AJ, Miwa S, Murphy MP, Pakay JL, Talbot DA & Echtay KS (2004) Mitochondrial superoxide and aging: uncoupling-protein activity and superoxide production. Biochem Soc Symp, 203-13

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