Found 437 results
Filters: Keyword is Mitochondria  [Clear All Filters]
Fearnley IM, Carroll J, Shannon RJ, Runswick MJ, Walker JE & Hirst J (2001) GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I). J Biol Chem 276, 38345-8
Dolce V, Fiermonte G, Runswick MJ, Palmieri F & Walker JE (2001) The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals. Proc Natl Acad Sci U S A 98, 2284-8
Palmieri L, Agrimi G, Runswick MJ, Fearnley IM, Palmieri F & Walker JE (2001) Identification in Saccharomyces cerevisiae of two isoforms of a novel mitochondrial transporter for 2-oxoadipate and 2-oxoglutarate. J Biol Chem 276, 1916-22
Fiermonte G, Dolce V, Palmieri L, Ventura M, Runswick MJ, Palmieri F & Walker JE (2001) Identification of the human mitochondrial oxodicarboxylate carrier. Bacterial expression, reconstitution, functional characterization, tissue distribution, and chromosomal location. J Biol Chem 276, 8225-30
Stuart JA, Cadenas S, Jekabsons MB, Roussel D & Brand MD (2001) Mitochondrial proton leak and the uncoupling protein 1 homologues. Biochim Biophys Acta 1504, 144-58
Harper JA, Dickinson K & Brand MD (2001) Mitochondrial uncoupling as a target for drug development for the treatment of obesity. Obes Rev 2, 255-65
Arechaga I, Ledesma A & Rial E (2001) The mitochondrial uncoupling protein UCP1: a gated pore. IUBMB Life 52, 165-73
Stuart JA, Harper JA, Brindle KM, Jekabsons MB & Brand MD (2001) Physiological levels of mammalian uncoupling protein 2 do not uncouple yeast mitochondria. J Biol Chem 276, 18633-9
Kelso GF, Porteous CM, Coulter CV, Hughes G, Porteous WK, Ledgerwood EC, Smith RA & Murphy MP (2001) Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties. J Biol Chem 276, 4588-96
Menz RI, Leslie AG & Walker JE (2001) The structure and nucleotide occupancy of bovine mitochondrial F(1)-ATPase are not influenced by crystallisation at high concentrations of nucleotide. FEBS Lett 494, 11-4
Cabezón E, Runswick MJ, Leslie AG & Walker JE (2001) The structure of bovine IF(1), the regulatory subunit of mitochondrial F-ATPase. EMBO J 20, 6990-6
Menz RI, Walker JE & Leslie AG (2001) Structure of bovine mitochondrial F(1)-ATPase with nucleotide bound to all three catalytic sites: implications for the mechanism of rotary catalysis. Cell 106, 331-41
Muratovska A, Lightowlers RN, Taylor RW, Wilce JA & Murphy MP (2001) Targeting large molecules to mitochondria. Adv Drug Deliv Rev 49, 189-98
Muratovska A, Lightowlers RN, Taylor RW, Turnbull DM, Smith RA, Wilce JA, Martin SW & Murphy MP (2001) Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease. Nucleic Acids Res 29, 1852-63
Cadenas S, Buckingham JA, St-Pierre J, Dickinson K, Jones RB & Brand MD (2000) AMP decreases the efficiency of skeletal-muscle mitochondria. Biochem J 351 Pt 2, 307-11
Cadenas S & Brand MD (2000) Effects of magnesium and nucleotides on the proton conductance of rat skeletal-muscle mitochondria. Biochem J 348 Pt 1, 209-13
Kajander OA, Rovio AT, Majamaa K, Poulton J, Spelbrink JN, Holt IJ, Karhunen PJ & Jacobs HT (2000) Human mtDNA sublimons resemble rearranged mitochondrial genoms found in pathological states. Hum Mol Genet 9, 2821-35
Palmieri L, Lasorsa FM, Vozza A, Agrimi G, Fiermonte G, Runswick MJ, Walker JE & Palmieri F (2000) Identification and functions of new transporters in yeast mitochondria. Biochim Biophys Acta 1459, 363-9
Clapham JC, Arch JR, Chapman H, Haynes A, Lister C, Moore GB, Piercy V, Carter SA, Lehner I, Smith SA, Beeley LJ, Godden RJ, Herrity N, Skehel M, Changani KK, Hockings PD, Reid DG, Squires SM, Hatcher J, Trail B, Latcham J, Rastan S, Harper AJ, Cadenas S, Buckingham JA, Brand MD & Abuin A (2000) Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean. Nature 406, 415-8
Bishop T & Brand MD (2000) Processes contributing to metabolic depression in hepatopancreas cells from the snail Helix aspersa. J Exp Biol 203, 3603-12
Braig K, Menz RI, Montgomery MG, Leslie AG & Walker JE (2000) Structure of bovine mitochondrial F(1)-ATPase inhibited by Mg(2+) ADP and aluminium fluoride. Structure 8, 567-73
Gibbons C, Montgomery MG, Leslie AG & Walker JE (2000) The structure of the central stalk in bovine F(1)-ATPase at 2.4 A resolution. Nat Struct Biol 7, 1055-61
Buttgereit F, Burmester GR & Brand MD (2000) Therapeutically targeting lymphocyte energy metabolism by high-dose glucocorticoids. Biochem Pharmacol 59, 597-603
Brand MD (2000) Uncoupling to survive? The role of mitochondrial inefficiency in ageing. Exp Gerontol 35, 811-20
Palmieri L, Runswick MJ, Fiermonte G, Walker JE & Palmieri F (2000) Yeast mitochondrial carriers: bacterial expression, biochemical identification and metabolic significance. J Bioenerg Biomembr 32, 67-77