Publications

Found 642 results
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2015
Peters OM, Ghasemi M & Brown RH (2015) Emerging mechanisms of molecular pathology in ALS. J Clin Invest 125, 1767-1779
Menger KE, James AM, Cochemé HM, Harbour ME, Chouchani ET, Ding S, Fearnley IM, Partridge L & Murphy MP (2015) Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster. Cell Rep 11, 1856-65
Pancrazi L, Di Benedetto G, Colombaioni L, Sala GDella, Testa G, Olimpico F, Reyes A, Zeviani M, Pozzan T & Costa M (2015) Foxg1 localizes to mitochondria and coordinates cell differentiation and bioenergetics. Proc Natl Acad Sci U S A 112, 13910-5
Bason JV, Montgomery MG, Leslie AGW & Walker JE (2015) How release of phosphate from mammalian F1-ATPase generates a rotary substep. Proc Natl Acad Sci U S A 112, 6009-14
Meyer K, Buettner S, Ghezzi D, Zeviani M, Bano D & Nicotera P (2015) Loss of apoptosis-inducing factor critically affects MIA40 function. Cell Death Dis 6, e1814
Kelly B, Tannahill GM, Murphy MP & O'Neill LAJ (2015) Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated Macrophages. J Biol Chem 290, 20348-59
Del Amo VLopez, Seco-Cervera M, Garcia-Gimenez JLuis, Whitworth AJ, Pallardo FV & Galindo MIbo (2015) Mitochondrial defects and neuromuscular degeneration caused by altered expression of Drosophila Gdap1: implications for the Charcot-Marie-Tooth neuropathy. Hum Mol Genet 24, 21-36
Keogh MJ & Chinnery PF (2015) Mitochondrial DNA mutations in neurodegeneration. Biochim Biophys Acta 1847, 1401-11
Vanderperre B, Bender T, Kunji ERS & Martinou J-C (2015) Mitochondrial pyruvate import and its effects on homeostasis. Curr Opin Cell Biol 33, 35-41
Dare AJ, Logan A, Prime TA, Rogatti S, Goddard M, Bolton EM, J Bradley A, Pettigrew GJ, Murphy MP & Saeb-Parsy K (2015) The mitochondria-targeted anti-oxidant MitoQ decreases ischemia-reperfusion injury in a murine syngeneic heart transplant model. J Heart Lung Transplant 34, 1471-80
Powell RD, Swet JH, Kennedy KL, Huynh TT, Murphy MP, Mckillop IH & Evans SL (2015) MitoQ modulates oxidative stress and decreases inflammation following hemorrhage. J Trauma Acute Care Surg 78, 573-9
Hämäläinen RH, Ahlqvist KJ, Ellonen P, Lepistö M, Logan A, Otonkoski T, Murphy MP & Suomalainen A (2015) mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling. Cell Rep 11, 1614-24
Bee L, Nasca A, Zanolini A, Cendron F, D'Adamo P, Costa R, Lamperti C, Celotti L, Ghezzi D & Zeviani M (2015) A nonsense mutation of human XRCC4 is associated with adult-onset progressive encephalocardiomyopathy. EMBO Mol Med 7, 918-29
Civiletto G, Varanita T, Cerutti R, Gorletta T, Barbaro S, Marchet S, Lamperti C, Viscomi C, Scorrano L & Zeviani M (2015) Opa1 overexpression ameliorates the phenotype of two mitochondrial disease mouse models. Cell Metab 21, 845-54
Varanita T, Soriano MEugenia, Romanello V, Zaglia T, Quintana-Cabrera R, Semenzato M, Menabò R, Costa V, Civiletto G, Pesce P, Viscomi C, Zeviani M, Di Lisa F, Mongillo M, Sandri M & Scorrano L (2015) The OPA1-dependent mitochondrial cristae remodeling pathway controls atrophic, apoptotic, and ischemic tissue damage. Cell Metab 21, 834-44
Lee J, Ding S, Walpole TB, Holding AN, Montgomery MG, Fearnley IM & Walker JE (2015) Organization of Subunits in the Membrane Domain of the Bovine F-ATPase Revealed by Covalent Cross-linking. J Biol Chem 290, 13308-20
Wiegman CH, Michaeloudes C, Haji G, Narang P, Clarke CJ, Russell KE, Bao W, Pavlidis S, Barnes PJ, Kanerva J, Bittner A, Rao N, Murphy MP, Kirkham PA, Chung KFan & Adcock IM (2015) Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease. J Allergy Clin Immunol 136, 769-80
J Holmes B, Akman G, Wood SR, Sakhuja K, Cerritelli SM, Moss C, Bowmaker MR, Jacobs HT, Crouch RJ & Holt IJ (2015) Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication. Proc Natl Acad Sci U S A 112, 9334-9
Dare AJ, Bolton EA, Pettigrew GJ, J Bradley A, Saeb-Parsy K & Murphy MP (2015) Protection against renal ischemia-reperfusion injury in vivo by the mitochondria targeted antioxidant MitoQ. Redox Biol 5, 163-168
Liu S, Charlesworth TJ, Bason JV, Montgomery MG, Harbour ME, Fearnley IM & Walker JE (2015) The purification and characterization of ATP synthase complexes from the mitochondria of four fungal species. Biochem J 468, 167-75
Willems PHGM, Rossignol R, Dieteren CEJ, Murphy MP & Koopman WJH (2015) Redox Homeostasis and Mitochondrial Dynamics. Cell Metab 22, 207-18
Kadariya I, Wang J, Rehman Zur, Ali H, Riaz H, He J, Bhattarai D, Liu JJia & Zhang SJun (2015) RNAi-mediated knockdown of inhibin α subunit increased apoptosis in granulosa cells and decreased fertility in mice. J Steroid Biochem Mol Biol 152, 161-70
Zhou A, Rohou A, Schep DG, Bason JV, Montgomery MG, Walker JE, Grigorieff N & Rubinstein JL (2015) Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM. Elife 4, e10180
Zhu J, King MS, Yu M, Klipcan L, Leslie AGW & Hirst J (2015) Structure of subcomplex Iβ of mammalian respiratory complex I leads to new supernumerary subunit assignments. Proc Natl Acad Sci U S A 112, 12087-92
Galarreta CI, Forbes MS, Thornhill BA, Antignac C, Gubler M-C, Nevo N, Murphy MP & Chevalier RL (2015) The swan-neck lesion: proximal tubular adaptation to oxidative stress in nephropathic cystinosis. Am J Physiol Renal Physiol 308, F1155-66

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