Publications

Found 79 results
Filters: Keyword is Oxidative Stress  [Clear All Filters]
2007
Lambert AJ & Brand MD (2007) Research on mitochondria and aging, 2006-2007. Aging Cell 6, 417-20
Brown SE, Ross MF, Sanjuan-Pla A, Manas A-RB, Smith RAJ & Murphy MP (2007) Targeting lipoic acid to mitochondria: synthesis and characterization of a triphenylphosphonium-conjugated alpha-lipoyl derivative. Free Radic Biol Med 42, 1766-80
Baines CP, Kaiser RA, Sheiko T, Craigen WJ & Molkentin JD (2007) Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death. Nat Cell Biol 9, 550-5
2006
Magwere T, West M, Riyahi K, Murphy MP, Smith RAJ & Partridge L (2006) The effects of exogenous antioxidants on lifespan and oxidative stress resistance in Drosophila melanogaster. Mech Ageing Dev 127, 356-70
Pierre F, Peiro G, Taché S, Cross AJ, Bingham SA, Gasc N, Gottardi G, Corpet DE & Guéraud F (2006) New marker of colon cancer risk associated with heme intake: 1,4-dihydroxynonane mercapturic acid. Cancer Epidemiol Biomarkers Prev 15, 2274-9
2005
Meulener M, Whitworth AJ, Armstrong-Gold CE, Rizzu P, Heutink P, Wes PD, Pallanck LJ & Bonini NM (2005) Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease. Curr Biol 15, 1572-7
Greene JC, Whitworth AJ, Andrews LA, Parker TJ & Pallanck LJ (2005) Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis. Hum Mol Genet 14, 799-811
Echtay KS, Pakay JL, Esteves TC & Brand MD (2005) Hydroxynonenal and uncoupling proteins: a model for protection against oxidative damage. Biofactors 24, 119-30
James AM, Cochemé HM, Smith RAJ & Murphy MP (2005) Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools. J Biol Chem 280, 21295-312
Kujoth GC, Hiona A, Pugh TD, Someya S, Panzer K, Wohlgemuth SE, Hofer T, Seo AY, Sullivan R, Jobling WA, Morrow JD, Van Remmen H, Sedivy JM, Yamasoba T, Tanokura M, Weindruch R, Leeuwenburgh C & Prolla TA (2005) Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 309, 481-4
James AM, Cochemé HM & Murphy MP (2005) Mitochondria-targeted redox probes as tools in the study of oxidative damage and ageing. Mech Ageing Dev 126, 982-6
Bianchi P, Pimentel DR, Murphy MP, Colucci WS & Parini A (2005) A new hypertrophic mechanism of serotonin in cardiac myocytes: receptor-independent ROS generation. FASEB J 19, 641-3
Brand MD & Esteves TC (2005) Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3. Cell Metab 2, 85-93
Canoy D, Wareham N, Welch A, Bingham S, Luben R, Day N & Khaw K-T (2005) Plasma ascorbic acid concentrations and fat distribution in 19,068 British men and women in the European Prospective Investigation into Cancer and Nutrition Norfolk cohort study. Am J Clin Nutr 82, 1203-9
2004
Beer SM, Taylor ER, Brown SE, Dahm CC, Costa NJ, Runswick MJ & Murphy MP (2004) Glutaredoxin 2 catalyzes the reversible oxidation and glutathionylation of mitochondrial membrane thiol proteins: implications for mitochondrial redox regulation and antioxidant DEFENSE. J Biol Chem 279, 47939-51
Murphy MP (2004) Investigating mitochondrial radical production using targeted probes. Biochem Soc Trans 32, 1011-4
King A, Gottlieb E, Brooks DG, Murphy MP & Dunaief JL (2004) Mitochondria-derived reactive oxygen species mediate blue light-induced death of retinal pigment epithelial cells. Photochem Photobiol 79, 470-5
Chen K, Thomas SR, Albano A, Murphy MP & Keaney JF (2004) Mitochondrial function is required for hydrogen peroxide-induced growth factor receptor transactivation and downstream signaling. J Biol Chem 279, 35079-86
Green K, Brand MD & Murphy MP (2004) Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes. Diabetes 53 Suppl 1, S110-8
2003
Jauslin ML, Meier T, Smith RAJ & Murphy MP (2003) Mitochondria-targeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants. FASEB J 17, 1972-4
Saretzki G, Murphy MP & von Zglinicki T (2003) MitoQ counteracts telomere shortening and elongates lifespan of fibroblasts under mild oxidative stress. Aging Cell 2, 141-3
Bedogni B, Pani G, Colavitti R, Riccio A, Borrello S, Murphy M, Smith R, Eboli MLuisa & Galeotti T (2003) Redox regulation of cAMP-responsive element-binding protein and induction of manganous superoxide dismutase in nerve growth factor-dependent cell survival. J Biol Chem 278, 16510-9
Taylor ER, Hurrell F, Shannon RJ, Lin T-K, Hirst J & Murphy MP (2003) Reversible glutathionylation of complex I increases mitochondrial superoxide formation. J Biol Chem 278, 19603-10
2002
James AM & Murphy MP (2002) How mitochondrial damage affects cell function. J Biomed Sci 9, 475-87
Brand MD, Pamplona R, Portero-Otín M, Requena JR, Roebuck SJ, Buckingham JA, Clapham JC & Cadenas S (2002) Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3. Biochem J 368, 597-603

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