Publications

Found 108 results
Filters: Keyword is Reactive Oxygen Species  [Clear All Filters]
2009
Humphrey DM, Toivonen JM, Giannakou M, Partridge L & Brand MD (2009) Expression of human uncoupling protein-3 in Drosophila insulin-producing cells increases insulin-like peptide (DILP) levels and shortens lifespan. Exp Gerontol 44, 316-27
Fernandez-Ayala DJM, Sanz A, Vartiainen S, Kemppainen KK, Babusiak M, Mustalahti E, Costa R, Tuomela T, Zeviani M, Chung J, O'Dell KMC, Rustin P & Jacobs HT (2009) Expression of the Ciona intestinalis alternative oxidase (AOX) in Drosophila complements defects in mitochondrial oxidative phosphorylation. Cell Metab 9, 449-60
Murphy MP (2009) How mitochondria produce reactive oxygen species. Biochem J 417, 1-13
Ricart KC, Bolisetty S, Johnson MS, Perez J, Agarwal A, Murphy MP & Landar A (2009) The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cells. Biochem J 419, 427-36
Lambert AJ & Brand MD (2009) Reactive oxygen species production by mitochondria. Methods Mol Biol 554, 165-81
King MS, Sharpley MS & Hirst J (2009) Reduction of hydrophilic ubiquinones by the flavin in mitochondrial NADH:ubiquinone oxidoreductase (Complex I) and production of reactive oxygen species. Biochemistry 48, 2053-62
Berrisford JM & Sazanov LA (2009) Structural basis for the mechanism of respiratory complex I. J Biol Chem 284, 29773-83
2007
Echtay KS & Brand MD (2007) 4-hydroxy-2-nonenal and uncoupling proteins: an approach for regulation of mitochondrial ROS production. Redox Rep 12, 26-9
Vergani L, Malena A, Sabatelli P, Loro E, Cavallini L, Magalhaes P, Valente L, Bragantini F, Carrara F, Leger B, Poulton J, Russell AP & Holt IJ (2007) Cultured muscle cells display defects of mitochondrial myopathy ameliorated by anti-oxidants. Brain 130, 2715-24
Hurd TR, Prime TA, Harbour ME, Lilley KS & Murphy MP (2007) Detection of reactive oxygen species-sensitive thiol proteins by redox difference gel electrophoresis: implications for mitochondrial redox signaling. J Biol Chem 282, 22040-51
Floyd S, Favre C, Lasorsa FM, Leahy M, Trigiante G, Stroebel P, Marx A, Loughran G, O'Callaghan K, Marobbio CMT, Slotboom DJ, Kunji ERS, Palmieri F & O'Connor R (2007) The insulin-like growth factor-I-mTOR signaling pathway induces the mitochondrial pyrimidine nucleotide carrier to promote cell growth. Mol Biol Cell 18, 3545-55
Lambert AJ, Boysen HM, Buckingham JA, Yang T, Podlutsky A, Austad SN, Kunz TH, Buffenstein R & Brand MD (2007) Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms. Aging Cell 6, 607-18
Affourtit C, Crichton PG, Parker N & Brand MD (2007) Novel uncoupling proteins. Novartis Found Symp 287, 70-80; discussion 80-91
Bell EL, Klimova TA, Eisenbart J, Moraes CT, Murphy MP, Budinger GRScott & Chandel NS (2007) The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production. J Cell Biol 177, 1029-36
Lambert AJ & Brand MD (2007) Research on mitochondria and aging, 2006-2007. Aging Cell 6, 417-20
Murphy MP & Smith RAJ (2007) Targeting antioxidants to mitochondria by conjugation to lipophilic cations. Annu Rev Pharmacol Toxicol 47, 629-56
Brown SE, Ross MF, Sanjuan-Pla A, Manas A-RB, Smith RAJ & Murphy MP (2007) Targeting lipoic acid to mitochondria: synthesis and characterization of a triphenylphosphonium-conjugated alpha-lipoyl derivative. Free Radic Biol Med 42, 1766-80
2006
Watanabe N, Zmijewski JW, Takabe W, Umezu-Goto M, Le Goffe C, Sekine A, Landar A, Watanabe A, Aoki J, Arai H, Kodama T, Murphy MP, Kalyanaraman R, Darley-Usmar VM & Noguchi N (2006) Activation of mitogen-activated protein kinases by lysophosphatidylcholine-induced mitochondrial reactive oxygen species generation in endothelial cells. Am J Pathol 168, 1737-48
Iuso A, Scacco S, Piccoli C, Bellomo F, Petruzzella V, Trentadue R, Minuto M, Ripoli M, Capitanio N, Zeviani M & Papa S (2006) Dysfunctions of cellular oxidative metabolism in patients with mutations in the NDUFS1 and NDUFS4 genes of complex I. J Biol Chem 281, 10374-80

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