Publications

Found 641 results
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2003
Krause MM, Brand MD, Krauss S, Meisel C, Vergin H, Burmester G-R & Buttgereit F (2003) Nonsteroidal antiinflammatory drugs and a selective cyclooxygenase 2 inhibitor uncouple mitochondria in intact cells. Arthritis Rheum 48, 1438-44
Hirst J, Carroll J, Fearnley IM, Shannon RJ & Walker JE (2003) The nuclear encoded subunits of complex I from bovine heart mitochondria. Biochim Biophys Acta 1604, 135-50
Brand MD, Turner N, Ocloo A, Else PL & Hulbert AJ (2003) Proton conductance and fatty acyl composition of liver mitochondria correlates with body mass in birds. Biochem J 376, 741-8
Smith VR & Walker JE (2003) Purification and folding of recombinant bovine oxoglutarate/malate carrier by immobilized metal-ion affinity chromatography. Protein Expr Purif 29, 209-16
Bedogni B, Pani G, Colavitti R, Riccio A, Borrello S, Murphy M, Smith R, Eboli MLuisa & Galeotti T (2003) Redox regulation of cAMP-responsive element-binding protein and induction of manganous superoxide dismutase in nerve growth factor-dependent cell survival. J Biol Chem 278, 16510-9
Taylor ER, Hurrell F, Shannon RJ, Lin T-K, Hirst J & Murphy MP (2003) Reversible glutathionylation of complex I increases mitochondrial superoxide formation. J Biol Chem 278, 19603-10
Echtay KS, Esteves TC, Pakay JL, Jekabsons MB, Lambert AJ, Portero-Otín M, Pamplona R, Vidal-Puig AJ, Wang S, Roebuck SJ & Brand MD (2003) A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling. EMBO J 22, 4103-10
James AM, Blaikie FH, Smith RAJ, Lightowlers RN, Smith PM & Murphy MP (2003) Specific targeting of a DNA-alkylating reagent to mitochondria. Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide. Eur J Biochem 270, 2827-36
Cabezon E, Montgomery MG, Leslie AGW & Walker JE (2003) The structure of bovine F1-ATPase in complex with its regulatory protein IF1. Nat Struct Biol 10, 744-50
Pebay-Peyroula E, Dahout-Gonzalez C, Kahn R, Trézéguet V, Lauquin GJ-M & Brandolin G (2003) Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside. Nature 426, 39-44
Rubinstein JL, Walker JE & Henderson R (2003) Structure of the mitochondrial ATP synthase by electron cryomicroscopy. EMBO J 22, 6182-92
Talbot DA, Hanuise N, Rey B, Rouanet J-L, Duchamp C & Brand MD (2003) Superoxide activates a GDP-sensitive proton conductance in skeletal muscle mitochondria from king penguin (Aptenodytes patagonicus). Biochem Biophys Res Commun 312, 983-8
Murphy MP, Echtay KS, Blaikie FH, Asin-Cayuela J, Cochemé HM, Green K, Buckingham JA, Taylor ER, Hurrell F, Hughes G, Miwa S, Cooper CE, Svistunenko DA, Smith RAJ & Brand MD (2003) Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone. J Biol Chem 278, 48534-45
Miwa S, St-Pierre J, Partridge L & Brand MD (2003) Superoxide and hydrogen peroxide production by Drosophila mitochondria. Free Radic Biol Med 35, 938-48
Whitworth AJ & Russell S (2003) Temporally dynamic response to Wingless directs the sequential elaboration of the proximodistal axis of the Drosophila wing. Dev Biol 254, 277-88
Rubinstein JL, Holt LJ, Walker JE & Tomlinson IM (2003) Use of phage display and high-density screening for the isolation of an antibody against the 51-kDa subunit of complex I. Anal Biochem 314, 294-300
Smith RAJ, Kelso GF, Blaikie FH, Porteous CM, Ledgerwood EC, Hughes G, James AM, Ross MF, Asin-Cayuela J, Cochemé HM, Filipovska A & Murphy MP (2003) Using mitochondria-targeted molecules to study mitochondrial radical production and its consequences. Biochem Soc Trans 31, 1295-9
2002
Harper JA, Stuart JA, Jekabsons MB, Roussel D, Brindle KM, Dickinson K, Jones RB & Brand MD (2002) Artifactual uncoupling by uncoupling protein 3 in yeast mitochondria at the concentrations found in mouse and rat skeletal-muscle mitochondria. Biochem J 361, 49-56
Cadenas S, Echtay KS, Harper JA, Jekabsons MB, Buckingham JA, Grau E, Abuin A, Chapman H, Clapham JC & Brand MD (2002) The basal proton conductance of skeletal muscle mitochondria from transgenic mice overexpressing or lacking uncoupling protein-3. J Biol Chem 277, 2773-8
Yang MYao, Bowmaker M, Reyes A, Vergani L, Angeli P, Gringeri E, Jacobs HT & Holt IJ (2002) Biased incorporation of ribonucleotides on the mitochondrial L-strand accounts for apparent strand-asymmetric DNA replication. Cell 111, 495-505
van der Giezen M, Slotboom DJan, Horner DS, Dyal PL, Harding M, Xue G-P, T Embley M & Kunji ERS (2002) Conserved properties of hydrogenosomal and mitochondrial ADP/ATP carriers: a common origin for both organelles. EMBO J 21, 572-9
Carroll J, Shannon RJ, Fearnley IM, Walker JE & Hirst J (2002) Definition of the nuclear encoded protein composition of bovine heart mitochondrial complex I. Identification of two new subunits. J Biol Chem 277, 50311-7
Elliott SJ, Léger C, Pershad HR, Hirst J, Heffron K, Ginet N, Blasco F, Rothery RA, Weiner JH & Armstrong FA (2002) Detection and interpretation of redox potential optima in the catalytic activity of enzymes. Biochim Biophys Acta 1555, 54-9
Roussel D, Harding M, Runswick MJ, Walker JE & Brand MD (2002) Does any yeast mitochondrial carrier have a native uncoupling protein function?. J Bioenerg Biomembr 34, 165-76
Bingham SAnne, Hughes R & Cross AJane (2002) Effect of white versus red meat on endogenous N-nitrosation in the human colon and further evidence of a dose response. J Nutr 132, 3522S-3525S

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