Publications

Found 1895 results
2018
Kullar PJ, Gomez-Duran A, Gammage PA, Garone C, Minczuk M, Golder Z, Wilson J, Montoya J, Häkli S, Kärppä M, Horvath R, Majamaa K & Chinnery PF (2018) Heterozygous SSBP1 start loss mutation co-segregates with hearing loss and the m.1555A>G mtDNA variant in a large multigenerational family. Brain 141, 55-62
Keogh MJ, Wei W, Aryaman J, Walker L, van den Ameele J, Coxhead J, Wilson I, Bashton M, Beck J, West J, Chen R, Haudenschild C, Bartha G, Luo S, Morris CM, Jones NS, Attems J & Chinnery PF (2018) High prevalence of focal and multi-focal somatic genetic variants in the human brain. Nat Commun 9, 4257
Kurauskas V, Hessel A, Ma P, Lunetti P, Weinhäupl K, Imbert L, Brutscher B, King MS, Sounier R, Dolce V, Kunji ERS, Capobianco L, Chipot C, Dehez F, Bersch B & Schanda P (2018) How Detergent Impacts Membrane Proteins: Atomic-Level Views of Mitochondrial Carriers in Dodecylphosphocholine. J Phys Chem Lett 9, 933-938
Ghezzi D & Zeviani M (2018) Human diseases associated with defects in assembly of OXPHOS complexes. Essays Biochem 62, 271-286
Pak O, Scheibe S, Esfandiary A, Gierhardt M, Sydykov A, Logan A, Fysikopoulos A, Veit F, Hecker M, Kroschel F, Quanz K, Erb A, Schäfer K, Fassbinder M, Alebrahimdehkordi N, Ghofrani HA, Schermuly RT, Brandes RP, Seeger W, Murphy MP, Weissmann N & Sommer N (2018) Impact of the mitochondria-targeted antioxidant MitoQ on hypoxia-induced pulmonary hypertension. Eur Respir J
Molina JR, Sun Y, Protopopova M, Gera S, Bandi M, Bristow C, McAfoos T, Morlacchi P, Ackroyd J, Agip A-NA, Al-Atrash G, Asara J, Bardenhagen J, Carrillo CC, Carroll C, Chang E, Ciurea S, Cross JB, Czako B, Deem A, Daver N, de Groot JFrederick, Dong J-W, Feng N, Gao G, Gay J, Do MGeck, Greer J, Giuliani V, Han J, Han L, Henry VK, Hirst J, Huang S, Jiang Y, Kang Z, Khor T, Konoplev S, Lin Y-H, Liu G, Lodi A, Lofton T, Ma H, Mahendra M, Matre P, Mullinax R, Peoples M, Petrocchi A, Rodriguez-Canale J, Serreli R, Shi T, Smith M, Tabe Y, Theroff J, Tiziani S, Xu Q, Zhang Q, Muller F, DePinho RA, Toniatti C, Draetta GF, Heffernan TP, Konopleva M, Jones P, M Di Francesco E & Marszalek JR (2018) An inhibitor of oxidative phosphorylation exploits cancer vulnerability. Nat Med
Pell VR, Spiroski A-M, Mulvey J, Burger N, Costa ASH, Logan A, Gruszczyk AV, Rosa T, James AM, Frezza C, Murphy MP & Krieg T (2018) Ischemic preconditioning protects against cardiac ischemia reperfusion injury without affecting succinate accumulation or oxidation. J Mol Cell Cardiol 123, 88-91
Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sévin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP & O'Neill LA (2018) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature 556, 113-117
Murphy MP & O'Neill LAJ (2018) Krebs Cycle Reimagined: The Emerging Roles of Succinate and Itaconate as Signal Transducers. Cell 174, 780-784
Buffin S, Ikhelef N, Prudent J, Dubayle J, Nougarede N, Varenne M-P, Moste C & Legastelois I (2018) A latex agglutination assay to quantify the amount of hemagglutinin protein in adjuvanted low-dose influenza monovalent vaccines. J Virol Methods 251, 46-53
Sun Y, Zhang H, Xing X, Zhao Z, He J, Li J, Chen J, Wang M & He Y (2018) Lead promotes abnormal angiogenesis induced by CCM3 gene defects via mitochondrial pathway. J Dev Orig Health Dis 9, 182-190
Kim USamuel, Jurkute N & Yu-Wai-Man P (2018) Leber Hereditary Optic Neuropathy-Light at the End of the Tunnel?. Asia Pac J Ophthalmol (Phila) 7, 242-245
Deepa SS, Pharaoh G, Kinter M, Diaz V, Fok WC, Riddle K, Pulliam D, Hill S, Fischer KE, Soto V, Georgescu C, Wren JD, Viscomi C, Richardson A & Van Remmen H (2018) Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice. Aging Cell, e12769
Peeva V, Blei D, Trombly G, Corsi S, Szukszto MJ, Rebelo-Guiomar P, Gammage PA, Kudin AP, Becker C, Altmüller J, Minczuk MA, Zsurka G & Kunz WS (2018) Linear mitochondrial DNA is rapidly degraded by components of the replication machinery. Nat Commun 9, 1727
Peruzzotti-Jametti L, Bernstock JD, Vicario N, Costa ASH, Kwok CKeong, Leonardi T, Booty LM, Bicci I, Balzarotti B, Volpe G, Mallucci G, Manferrari G, Donegà M, Iraci N, Braga A, Hallenbeck JM, Murphy MP, Edenhofer F, Frezza C & Pluchino S (2018) Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation. Cell Stem Cell 22, 355-368.e13
Murphy MP (2018) Metabolic control of ferroptosis in cancer. Nat Cell Biol 20, 1104-1105
Kohlhauer M, Dawkins S, Costa ASH, Lee R, Young T, Pell VR, Choudhury RP, Banning AP, Kharbanda RK, Saeb-Parsy K, Murphy MP, Frezza C, Krieg T & Channon KM (2018) Metabolomic Profiling in Acute ST-Segment-Elevation Myocardial Infarction Identifies Succinate as an Early Marker of Human Ischemia-Reperfusion Injury. J Am Heart Assoc 7
Bargiela D, Burr SP & Chinnery PF (2018) Mitochondria and Hypoxia: Metabolic Crosstalk in Cell-Fate Decisions. Trends Endocrinol Metab 29, 249-259
Murphy MP & Hartley RC (2018) Mitochondria as a therapeutic target for common pathologies. Nat Rev Drug Discov
Brooks HR (2018) Mitochondria: Finding the Power to Change. Cell 175, 891-893
Hinchy EC, Gruszczyk AV, Willows R, Navaratnam N, Hall AR, Bates G, Bright TP, Krieg T, Carling D & Murphy MP (2018) Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly. J Biol Chem 293, 17208-17217
Zhang H, Burr SP & Chinnery PF (2018) The mitochondrial DNA genetic bottleneck: inheritance and beyond. Essays Biochem
Burr SP, Pezet M & Chinnery PF (2018) Mitochondrial DNA Heteroplasmy and Purifying Selection in the Mammalian Female Germ Line. Dev Growth Differ 60, 21-32
Tilokani L, Nagashima S, Paupe V & Prudent J (2018) Mitochondrial dynamics: overview of molecular mechanisms. Essays Biochem 62, 341-360
Aryaman J, Johnston IG & Jones NS (2018) Mitochondrial Heterogeneity. Front Genet 9, 718

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