Publications

Found 1969 results
2019
Booty LM, Gawel JM, Cvetko F, Caldwell ST, Hall AR, Mulvey JF, James AM, Hinchy EC, Prime TA, Arndt S, Benincá C, Bright TP, Clatworthy MR, Ferdinand JR, Prag HA, Logan A, Prudent J, Krieg T, Hartley RC & Murphy MP (2019) Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo. Cell Chem Biol 26, 449-461.e8
Burger N, Logan A, Prime TA, Mottahedin A, Caldwell ST, Krieg T, Hartley RC, James AM & Murphy MP (2019) A sensitive mass spectrometric assay for mitochondrial CoQ pool redox state in vivo. Free Radic Biol Med
Ruprecht JJ & Kunji ERS (2019) The SLC25 Mitochondrial Carrier Family: Structure and Mechanism. Trends Biochem Sci
Lau GY, Arndt S, Murphy MP & Richards JG (2019) Species and tissue specific differences in ROS metabolism to hypoxia- and hyperoxia-recovery exposure in marine sculpins. J Exp Biol
Jurkute N, Leu C, Pogoda H-M, Arno G, Robson AG, Nürnberg G, Altmüller J, Thiele H, Motameny S, Toliat MReza, Powell K, Höhne W, Michaelides M, Webster AR, Moore AT, Hammerschmidt M, Nürnberg P, Yu-Wai-Man P & Votruba M (2019) SSBP1 mutations in dominant optic atrophy with variable retinal degeneration. Ann Neurol
Ruprecht JJ & Kunji ERS (2019) Structural changes in the transport cycle of the mitochondrial ADP/ATP carrier. Curr Opin Struct Biol 57, 135-144
Guo H, Suzuki T & Rubinstein JL (2019) Structure of a bacterial ATP synthase. Elife 8
Petri J, Nakatani Y, Montgomery MG, Ferguson SA, Aragão D, Leslie AGW, Heikal A, Walker JE & Cook GM (2019) Structure of F-ATPase from the obligate anaerobe Fusobacterium nucleatum. Open Biol 9, 190066
Park J, Lee S-Y, Jeong H, Kang M-G, Van Haute L, Minczuk M, Seo JKon, Jun Y, Myung K, Rhee H-W & Lee C (2019) The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res 47, 7078-7093
Park J, Lee SY, Jeong H, Kang MG, Van Haute L, Minczuk M, Seo JKon, Jun Y, Myung K, Rhee H-W & Lee C (2019) The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res 47
Zhang AT, Montgomery MG, Leslie AGW, Cook GM & Walker JE (2019) The structure of the catalytic domain of the ATP synthase from Mycobacterium smegmatis is a target for developing antitubercular drugs. Proc Natl Acad Sci U S A
Martin JL, Costa ASH, Gruszczyk AV, Beach TE, Allen FM, Prag HA, Hinchy EC, Mahbubani K, Hamed M, Tronci L, Nikitopoulou E, James AM, Krieg T, Robinson AJ, Huang MM, Caldwell ST, Logan A, Pala L, Hartley RC, Frezza C, Saeb-Parsy K & Murphy MP (2019) Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation. Nature Metabolism 1, 966 - 974
Kula-Alwar D, Prag HA & Krieg T (2019) Targeting Succinate Metabolism in Ischemia/Reperfusion Injury. Circulation 140, 1968-1970
Kim Y-R, Baek J-I, Kim SHwan, Kim M-A, Lee B, Ryu N, Kim K-H, Choi D-G, Kim H-M, Murphy MP, Macpherson G, Choo Y-S, Bok J, Lee K-Y, Park J-W & Kim U-K (2019) Therapeutic potential of the mitochondria-targeted antioxidant MitoQ in mitochondrial-ROS induced sensorineural hearing loss caused by Idh2 deficiency. Redox Biol 20, 544-555
Jurkute N, Harvey J & Yu-Wai-Man P (2019) Treatment strategies for Leber hereditary optic neuropathy. Curr Opin Neurol 32, 99-104
Tavoulari S, Thangaratnarajah C, Mavridou V, Harbour ME, Martinou J-C & Kunji ERS (2019) The yeast mitochondrial pyruvate carrier is a hetero-dimer in its functional state. EMBO J 38
2018
Mills EL, Pierce KA, Jedrychowski MP, Garrity R, Winther S, Vidoni S, Yoneshiro T, Spinelli JB, Lu GZ, Kazak L, Banks AS, Haigis MC, Kajimura S, Murphy MP, Gygi SP, Clish CB & Chouchani ET (2018) Accumulation of succinate controls activation of adipose tissue thermogenesis. Nature 560, 102-106
Ferguson DCJ, Smerdon GR, Harries LW, Dodd NJF, Murphy MP, Curnow A & Winyard PG (2018) Altered cellular redox homeostasis and redox responses under standard oxygen cell culture conditions versus physioxia. Free Radic Biol Med 126, 322-333
Signes A & Fernandez-Vizarra E (2018) Assembly of mammalian oxidative phosphorylation complexes I-V and supercomplexes. Essays Biochem 62, 255-270
He J, Ford HC, Carroll J, Douglas C, Gonzales E, Ding S, Fearnley IM & Walker JE (2018) Assembly of the membrane domain of ATP synthase in human mitochondria. Proc Natl Acad Sci U S A
Montgomery MG, Gahura O, Leslie AGW, Zíková A & Walker JE (2018) ATP synthase fromhas an elaborated canonical F-domain and conventional catalytic sites. Proc Natl Acad Sci U S A 115, 2102-2107
Kim M, Stepanova A, Niatsetskaya Z, Sosunov S, Arndt S, Murphy MP, Galkin A & Ten VS (2018) Attenuation of oxidative damage by targeting mitochondrial complex I in neonatal hypoxic-ischemic brain injury. Free Radic Biol Med 124, 517-524
Lee JJ, Sanchez-Martinez A, Zarate AMartinez, Benincá C, Mayor U, Clague MJ & Whitworth AJ (2018) Basal mitophagy is widespread inbut minimally affected by loss of Pink1 or parkin. J Cell Biol
Harborne SPD & Kunji ERS (2018) Calcium-regulated mitochondrial ATP-Mg/P carriers evolved from a fusion of an EF-hand regulatory domain with a mitochondrial ADP/ATP carrier-like domain. IUBMB Life 70, 1222-1232
Duncan AL, Ruprecht JJ, Kunji ERS & Robinson AJ (2018) Cardiolipin dynamics and binding to conserved residues in the mitochondrial ADP/ATP carrier. Biochim Biophys Acta 1860, 1035-1045

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