Publications

Found 112 results
Filters: Keyword is Oxidation-Reduction  [Clear All Filters]
2005
Iwaki M, Yakovlev G, Hirst J, Osyczka A, P Dutton L, Marshall D & Rich PR (2005) Direct observation of redox-linked histidine protonation changes in the iron-sulfur protein of the cytochrome bc1 complex by ATR-FTIR spectroscopy. Biochemistry 44, 4230-7
Hurd TR, Filipovska A, Costa NJ, Dahm CC & Murphy MP (2005) Disulphide formation on mitochondrial protein thiols. Biochem Soc Trans 33, 1390-3
Hirst J (2005) Energy transduction by respiratory complex I--an evaluation of current knowledge. Biochem Soc Trans 33, 525-9
Hurd TR, Costa NJ, Dahm CC, Beer SM, Brown SE, Filipovska A & Murphy MP (2005) Glutathionylation of mitochondrial proteins. Antioxid Redox Signal 7, 999-1010
James AM, Cochemé HM, Smith RAJ & Murphy MP (2005) Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools. J Biol Chem 280, 21295-312
Kim A, Murphy MP & Oberley TD (2005) Mitochondrial redox state regulates transcription of the nuclear-encoded mitochondrial protein manganese superoxide dismutase: a proposed adaptive response to mitochondrial redox imbalance. Free Radic Biol Med 38, 644-54
James AM, Cochemé HM & Murphy MP (2005) Mitochondria-targeted redox probes as tools in the study of oxidative damage and ageing. Mech Ageing Dev 126, 982-6
Bianchi P, Pimentel DR, Murphy MP, Colucci WS & Parini A (2005) A new hypertrophic mechanism of serotonin in cardiac myocytes: receptor-independent ROS generation. FASEB J 19, 641-3
Hinchliffe P & Sazanov LA (2005) Organization of iron-sulfur clusters in respiratory complex I. Science 309, 771-4
Brand MD & Esteves TC (2005) Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3. Cell Metab 2, 85-93
Leggate EJ & Hirst J (2005) Roles of the disulfide bond and adjacent residues in determining the reduction potentials and stabilities of respiratory-type Rieske clusters. Biochemistry 44, 7048-58
Filipovska A, Kelso GF, Brown SE, Beer SM, Smith RAJ & Murphy MP (2005) Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic. Insights into the interaction of ebselen with mitochondria. J Biol Chem 280, 24113-26
2004
James AM, Smith RAJ & Murphy MP (2004) Antioxidant and prooxidant properties of mitochondrial Coenzyme Q. Arch Biochem Biophys 423, 47-56
Beer SM, Taylor ER, Brown SE, Dahm CC, Costa NJ, Runswick MJ & Murphy MP (2004) Glutaredoxin 2 catalyzes the reversible oxidation and glutathionylation of mitochondrial membrane thiol proteins: implications for mitochondrial redox regulation and antioxidant DEFENSE. J Biol Chem 279, 47939-51
Venkatraman A, Landar A, Davis AJ, Ulasova E, Page G, Murphy MP, Darley-Usmar V & Bailey SM (2004) Oxidative modification of hepatic mitochondria protein thiols: effect of chronic alcohol consumption. Am J Physiol Gastrointest Liver Physiol 286, G521-7
Smith RAJ, Kelso GF, James AM & Murphy MP (2004) Targeting coenzyme Q derivatives to mitochondria. Methods Enzymol 382, 45-67
2003
Hirst J (2003) The dichotomy of complex I: a sodium ion pump or a proton pump. Proc Natl Acad Sci U S A 100, 773-5
Costa NJ, Dahm CC, Hurrell F, Taylor ER & Murphy MP (2003) Interactions of mitochondrial thiols with nitric oxide. Antioxid Redox Signal 5, 291-305
Holt PJ, Morgan DJ & Sazanov LA (2003) The location of NuoL and NuoM subunits in the membrane domain of the Escherichia coli complex I: implications for the mechanism of proton pumping. J Biol Chem 278, 43114-20
Camba R, Jung Y-S, Hunsicker-Wang LM, Burgess BK, C Stout D, Hirst J & Armstrong FA (2003) Mechanisms of redox-coupled proton transfer in proteins: role of the proximal proline in reactions of the [3Fe-4S] cluster in Azotobacter vinelandii ferredoxin I. Biochemistry 42, 10589-99
Saretzki G, Murphy MP & von Zglinicki T (2003) MitoQ counteracts telomere shortening and elongates lifespan of fibroblasts under mild oxidative stress. Aging Cell 2, 141-3
Bedogni B, Pani G, Colavitti R, Riccio A, Borrello S, Murphy M, Smith R, Eboli MLuisa & Galeotti T (2003) Redox regulation of cAMP-responsive element-binding protein and induction of manganous superoxide dismutase in nerve growth factor-dependent cell survival. J Biol Chem 278, 16510-9
Zu Y, Couture MM-J, Kolling DRJ, Crofts AR, Eltis LD, Fee JA & Hirst J (2003) Reduction potentials of Rieske clusters: importance of the coupling between oxidation state and histidine protonation state. Biochemistry 42, 12400-8
Zu Y, Shannon RJ & Hirst J (2003) Reversible, electrochemical interconversion of NADH and NAD+ by the catalytic (Ilambda) subcomplex of mitochondrial NADH:ubiquinone oxidoreductase (complex I). J Am Chem Soc 125, 6020-1

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