Found 1971 results
Hinchy EC, Gruszczyk AV, Willows R, Navaratnam N, Hall AR, Bates G, Bright TP, Krieg T, Carling D & Murphy MP (2018) Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly. J Biol Chem 293, 17208-17217
Zhang H, Burr SP & Chinnery PF (2018) The mitochondrial DNA genetic bottleneck: inheritance and beyond. Essays Biochem
Burr SP, Pezet M & Chinnery PF (2018) Mitochondrial DNA Heteroplasmy and Purifying Selection in the Mammalian Female Germ Line. Dev Growth Differ 60, 21-32
Tilokani L, Nagashima S, Paupe V & Prudent J (2018) Mitochondrial dynamics: overview of molecular mechanisms. Essays Biochem 62, 341-360
Aryaman J, Johnston IG & Jones NS (2018) Mitochondrial Heterogeneity. Front Genet 9, 718
Lia D, Reyes A, Campos JTamara Ara, Piolot T, Baijer J, J Radicella P & Campalans A (2018) Mitochondrial maintenance under oxidative stress depends on mitochondrial but not nuclear α isoform of OGG1. J Cell Sci
Martin JL, Gruszczyk AV, Beach TE, Murphy MP & Saeb-Parsy K (2018) Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury. Pediatr Nephrol
Pacitti D, Levene M, Garone C, Nirmalananthan N & Bax BE (2018) Mitochondrial Neurogastrointestinal Encephalomyopathy: Into the Fourth Decade, What We Have Learned So Far. Front Genet 9, 669
Fazakerley DJ, Minard AY, Krycer JR, Thomas KC, Stöckli J, Harney DJ, Burchfield JG, Maghzal GJ, Caldwell ST, Hartley RC, Stocker R, Murphy MP & James DE (2018) Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation. J Biol Chem 293, 7315-7328
Boczonadi V, King MS, Smith AC, Oláhová M, Bansagi B, Roos A, Eyassu F, Borchers C, Ramesh V, Lochmüller H, Polvikoski T, Whittaker RG, Pyle A, Griffin H, Taylor RW, Chinnery PF, Robinson AJ, Kunji ERS & Horvath R (2018) Mitochondrial oxodicarboxylate carrier deficiency is associated with mitochondrial DNA depletion and spinal muscular atrophy-like disease. Genet Med 20, 1224-1235
Langer Y, Aran A, Gulsuner S, Libdeh BAbu, Renbaum P, Brunetti D, Teixeira P-F, Walsh T, Zeligson S, Ruotolo R, Beeri R, Dweikat I, Shahrour M, Weinberg-Shukron A, Zahdeh F, Baruffini E, Glaser E, King M-C, Levy-Lahad E, Zeviani M & Segel R (2018) Mitochondrial PITRM1 peptidase loss-of-function in childhood cerebellar atrophy. J Med Genet
Wilson RJ, Drake JC, Cui D, Lewellen BM, Fisher CC, Zhang M, Kashatus DF, Palmer LA, Murphy MP & Yan Z (2018) Mitochondrial protein S-nitrosation protects against ischemia reperfusion-induced denervation at neuromuscular junction in skeletal muscle. Free Radic Biol Med 117, 180-190
Sidlauskaite E, Gibson JW, Megson IL, Whitfield PD, Tovmasyan A, Batinic-Haberle I, Murphy MP, Moult PR & Cobley JN (2018) Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning. Redox Biol 16, 344-351
Kim J-H, Choi TGyu, Park S, Yun HRok, Nguyen NNgo Yen, Jo YHwa, Jang M, Kim J, Kim J, Kang I, Ha J, Murphy MP, Tang DG & Kim SSoo (2018) Mitochondrial ROS-derived PTEN oxidation activates PI3K pathway for mTOR-induced myogenic autophagy. Cell Death Differ
Fedor JG & Hirst J (2018) Mitochondrial Supercomplexes Do Not Enhance Catalysis by Quinone Channeling. Cell Metab 28, 525-531.e4
D'Souza AR & Minczuk MA (2018) Mitochondrial transcription and translation: overview. Essays Biochem 62, 309-320
Hofherr A, Seger C, Fitzpatrick F, Busch T, Michel E, Luan J, Osterried L, Linden F, Kramer-Zucker A, Wakimoto B, Schütze C, Wiedemann N, Artati A, Adamski J, Walz G, Kunji ERS, Montell C, Watnick T & Köttgen M (2018) The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism. PLoS Biol 16, e2005651
Gioscia-Ryan RA, Battson ML, Cuevas LM, Eng JS, Murphy MP & Seals DR (2018) Mitochondria-targeted antioxidant therapy with MitoQ ameliorates aortic stiffening in old mice. J Appl Physiol (1985) 124, 1194-1202
Junior RFaustino R, Dabkowski ERose, Shekar KChandra, Connell KAO, Hecker PA & Murphy MP (2018) MitoQ improves mitochondrial dysfunction in heart failure induced by pressure overload. Free Radic Biol Med 117, 18-29
Xi Y, Feng D, Tao K, Wang R, Shi Y, Qin H, Murphy MP, Yang Q & Zhao G (2018) MitoQ protects dopaminergic neurons in a 6-OHDA induced PD model by enhancing Mfn2-dependent mitochondrial fusion via activation of PGC-1α. Biochim Biophys Acta
Deshwal S, Forkink M, Hu C-H, Buonincontri G, Antonucci S, Di Sante M, Murphy MP, Paolocci N, Mochly-Rosen D, Krieg T, Di Lisa F & Kaludercic N (2018) Monoamine oxidase-dependent endoplasmic reticulum-mitochondria dysfunction and mast cell degranulation lead to adverse cardiac remodeling in diabetes. Cell Death Differ
Chinnery PF & Gomez-Duran A (2018) mtDNA Population Variants and Neurodegenerative Diseases. Front Neurosci 12, 682
Ng YShiau, Lax NZ, Maddison P, Alston CL, Blakely EL, Hepplewhite PD, Riordan G, Meldau S, Chinnery PF, Pierre G, Chronopoulou E, Du A, Hughes I, Morris AA, Kamakari S, Chrousos G, Rodenburg RJ, Saris CGJ, Feeney C, Hardy SA, Sakakibara T, Sudo A, Okazaki Y, Murayama K, Mundy H, Hanna MG, Ohtake A, Schaefer AM, Champion MP, Turnbull DM, Taylor RW, Pitceathly RDS, McFarland R & Gorman GS (2018) MT-ND5 Mutation Exhibits Highly Variable Neurological Manifestations at Low Mutant Load. EBioMedicine 30, 86-93
Bansagi B, Phan V, Baker MR, O'Sullivan J, Jennings MJ, Whittaker RG, Müller JS, Duff J, Griffin H, Miller JAL, Gorman GS, Lochmüller H, Chinnery PF, Roos A, Swan LE & Horvath R (2018) Multifocal demyelinating motor neuropathy and hamartoma syndrome associated with a de novo mutation. Neurology 90, e1842-e1848
Reyes A, Melchionda L, Burlina A, Robinson AJ, Ghezzi D & Zeviani M (2018) Mutations in compromise cell survival in OxPhos-dependent metabolic conditions. EMBO Mol Med