Publications

Found 426 results
Filters: Keyword is Mitochondria  [Clear All Filters]
2009
Holt IJ (2009) Mitochondrial DNA replication and repair: all a flap. Trends Biochem Sci 34, 358-65
Graham D, Huynh NN, Hamilton CA, Beattie E, Smith RAJ, Cochemé HM, Murphy MP & Dominiczak AF (2009) Mitochondria-targeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy. Hypertension 54, 322-8
Prime TA, Blaikie FH, Evans C, Nadtochiy SM, James AM, Dahm CC, Vitturi DA, Patel RP, C Hiley R, Abakumova I, Requejo R, Chouchani ET, Hurd TR, Garvey JF, Taylor CT, Brookes PS, Smith RAJ & Murphy MP (2009) A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury. Proc Natl Acad Sci U S A 106, 10764-9
Smith AC & Robinson AJ (2009) MitoMiner, an integrated database for the storage and analysis of mitochondrial proteomics data. Mol Cell Proteomics 8, 1324-37
Crichton PG, Parker N, Vidal-Puig AJ & Brand MD (2009) Not all mitochondrial carrier proteins support permeability transition pore formation: no involvement of uncoupling protein 1. Biosci Rep 30, 187-92
Ghezzi D, Viscomi C, Ferlini A, Gualandi F, Mereghetti P, DeGrandis D & Zeviani M (2009) Paroxysmal non-kinesigenic dyskinesia is caused by mutations of the MR-1 mitochondrial targeting sequence. Hum Mol Genet 18, 1058-64
Ricart KC, Bolisetty S, Johnson MS, Perez J, Agarwal A, Murphy MP & Landar A (2009) The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cells. Biochem J 419, 427-36
Whitworth AJ & Pallanck LJ (2009) The PINK1/Parkin pathway: a mitochondrial quality control system?. J Bioenerg Biomembr 41, 499-503
Tain LS, Mortiboys H, Tao RN, Ziviani E, Bandmann O & Whitworth AJ (2009) Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss. Nat Neurosci 12, 1129-35
Lambert AJ & Brand MD (2009) Reactive oxygen species production by mitochondria. Methods Mol Biol 554, 165-81
Maroz A, Anderson RF, Smith RAJ & Murphy MP (2009) Reactivity of ubiquinone and ubiquinol with superoxide and the hydroperoxyl radical: implications for in vivo antioxidant activity. Free Radic Biol Med 46, 105-9
Bridges HR, Grgic L, Harbour ME & Hirst J (2009) The respiratory complexes I from the mitochondria of two Pichia species. Biochem J 422, 151-9
Parker N, Crichton PG, Vidal-Puig AJ & Brand MD (2009) Uncoupling protein-1 (UCP1) contributes to the basal proton conductance of brown adipose tissue mitochondria. J Bioenerg Biomembr 41, 335-42
2008
Ashley N, O'Rourke A, Smith C, Adams S, Gowda V, Zeviani M, Brown GK, Fratter C & Poulton J (2008) Depletion of mitochondrial DNA in fibroblast cultures from patients with POLG1 mutations is a consequence of catalytic mutations. Hum Mol Genet 17, 2496-506
Minczuk M, Papworth MA, Miller JC, Murphy MP & Klug A (2008) Development of a single-chain, quasi-dimeric zinc-finger nuclease for the selective degradation of mutated human mitochondrial DNA. Nucleic Acids Res 36, 3926-38
Azzu V, Affourtit C, Breen EP, Parker N & Brand MD (2008) Dynamic regulation of uncoupling protein 2 content in INS-1E insulinoma cells. Biochim Biophys Acta 1777, 1378-83
Harper M-E, Green K & Brand MD (2008) The efficiency of cellular energy transduction and its implications for obesity. Annu Rev Nutr 28, 13-33
Ghezzi D, Saada A, D'Adamo P, Fernandez-Vizarra E, Gasparini P, Tiranti V, Elpeleg O & Zeviani M (2008) FASTKD2 nonsense mutation in an infantile mitochondrial encephalomyopathy associated with cytochrome c oxidase deficiency. Am J Hum Genet 83, 415-23
Azzu V, Parker N & Brand MD (2008) High membrane potential promotes alkenal-induced mitochondrial uncoupling and influences adenine nucleotide translocase conformation. Biochem J 413, 323-32
Lowes DA, Thottakam BMV, Webster NR, Murphy MP & Galley HF (2008) The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide-peptidoglycan model of sepsis. Free Radic Biol Med 45, 1559-65
Smith RAJ, Adlam VJ, Blaikie FH, Manas A-RB, Porteous CM, James AM, Ross MF, Logan A, Cochemé HM, Trnka J, Prime TA, Abakumova I, Jones BA, Filipovska A & Murphy MP (2008) Mitochondria-targeted antioxidants in the treatment of disease. Ann N Y Acad Sci 1147, 105-11
Trnka J, Blaikie FH, Smith RAJ & Murphy MP (2008) A mitochondria-targeted nitroxide is reduced to its hydroxylamine by ubiquinol in mitochondria. Free Radic Biol Med 44, 1406-19
Tsaousis AD, Kunji ERS, Goldberg AV, Lucocq JM, Hirt RP & T Embley M (2008) A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi. Nature 453, 553-6
Poole AC, Thomas RE, Andrews LA, McBride HM, Whitworth AJ & Pallanck LJ (2008) The PINK1/Parkin pathway regulates mitochondrial morphology. Proc Natl Acad Sci U S A 105, 1638-43
Cree LM, Samuels DC, Lopes SChuva de S, Rajasimha HKarur, Wonnapinij P, Mann JR, Dahl H-HM & Chinnery PF (2008) A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes. Nat Genet 40, 249-54

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