Publications

Found 437 results
Filters: Keyword is Mitochondria  [Clear All Filters]
2009
Tain LS, Chowdhury RB, Tao RN, Plun-Favreau H, Moisoi N, Martins LM, Downward J, Whitworth AJ & Tapon N (2009) Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin. Cell Death Differ 16, 1118-25
Fernandez-Ayala DJM, Sanz A, Vartiainen S, Kemppainen KK, Babusiak M, Mustalahti E, Costa R, Tuomela T, Zeviani M, Chung J, O'Dell KMC, Rustin P & Jacobs HT (2009) Expression of the Ciona intestinalis alternative oxidase (AOX) in Drosophila complements defects in mitochondrial oxidative phosphorylation. Cell Metab 9, 449-60
Mineri R, Pavelka N, Fernandez-Vizarra E, Ricciardi-Castagnoli P, Zeviani M & Tiranti V (2009) How do human cells react to the absence of mitochondrial DNA?. PLoS One 4, e5713
Murphy MP (2009) How mitochondria produce reactive oxygen species. Biochem J 417, 1-13
Malena A, Loro E, Di Re M, Holt IJ & Vergani L (2009) Inhibition of mitochondrial fission favours mutant over wild-type mitochondrial DNA. Hum Mol Genet 18, 3407-16
Tiranti V, Viscomi C, Hildebrandt T, Di Meo I, Mineri R, Tiveron C, Levitt MD, Prelle A, Fagiolari G, Rimoldi M & Zeviani M (2009) Loss of ETHE1, a mitochondrial dioxygenase, causes fatal sulfide toxicity in ethylmalonic encephalopathy. Nat Med 15, 200-5
Affourtit C & Brand MD (2009) Measuring mitochondrial bioenergetics in INS-1E insulinoma cells. Methods Enzymol 457, 405-24
Bailey LJ, Cluett TJ, Reyes A, Prolla TA, Poulton J, Leeuwenburgh C & Holt IJ (2009) Mice expressing an error-prone DNA polymerase in mitochondria display elevated replication pausing and chromosomal breakage at fragile sites of mitochondrial DNA. Nucleic Acids Res 37, 2327-35
Lowes DA, Wallace C, Murphy MP, Webster NR & Galley HF (2009) The mitochondria targeted antioxidant MitoQ protects against fluoroquinolone-induced oxidative stress and mitochondrial membrane damage in human Achilles tendon cells. Free Radic Res 43, 323-8
Holt IJ (2009) Mitochondrial DNA replication and repair: all a flap. Trends Biochem Sci 34, 358-65
Graham D, Huynh NN, Hamilton CA, Beattie E, Smith RAJ, Cochemé HM, Murphy MP & Dominiczak AF (2009) Mitochondria-targeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy. Hypertension 54, 322-8
Prime TA, Blaikie FH, Evans C, Nadtochiy SM, James AM, Dahm CC, Vitturi DA, Patel RP, C Hiley R, Abakumova I, Requejo R, Chouchani ET, Hurd TR, Garvey JF, Taylor CT, Brookes PS, Smith RAJ & Murphy MP (2009) A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury. Proc Natl Acad Sci U S A 106, 10764-9
Smith AC & Robinson AJ (2009) MitoMiner, an integrated database for the storage and analysis of mitochondrial proteomics data. Mol Cell Proteomics 8, 1324-37
Crichton PG, Parker N, Vidal-Puig AJ & Brand MD (2009) Not all mitochondrial carrier proteins support permeability transition pore formation: no involvement of uncoupling protein 1. Biosci Rep 30, 187-92
Ghezzi D, Viscomi C, Ferlini A, Gualandi F, Mereghetti P, DeGrandis D & Zeviani M (2009) Paroxysmal non-kinesigenic dyskinesia is caused by mutations of the MR-1 mitochondrial targeting sequence. Hum Mol Genet 18, 1058-64
Ricart KC, Bolisetty S, Johnson MS, Perez J, Agarwal A, Murphy MP & Landar A (2009) The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cells. Biochem J 419, 427-36
Whitworth AJ & Pallanck LJ (2009) The PINK1/Parkin pathway: a mitochondrial quality control system?. J Bioenerg Biomembr 41, 499-503
Tain LS, Mortiboys H, Tao RN, Ziviani E, Bandmann O & Whitworth AJ (2009) Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss. Nat Neurosci 12, 1129-35
Lambert AJ & Brand MD (2009) Reactive oxygen species production by mitochondria. Methods Mol Biol 554, 165-81
Maroz A, Anderson RF, Smith RAJ & Murphy MP (2009) Reactivity of ubiquinone and ubiquinol with superoxide and the hydroperoxyl radical: implications for in vivo antioxidant activity. Free Radic Biol Med 46, 105-9
Bridges HR, Grgic L, Harbour ME & Hirst J (2009) The respiratory complexes I from the mitochondria of two Pichia species. Biochem J 422, 151-9
Parker N, Crichton PG, Vidal-Puig AJ & Brand MD (2009) Uncoupling protein-1 (UCP1) contributes to the basal proton conductance of brown adipose tissue mitochondria. J Bioenerg Biomembr 41, 335-42
2008
Ashley N, O'Rourke A, Smith C, Adams S, Gowda V, Zeviani M, Brown GK, Fratter C & Poulton J (2008) Depletion of mitochondrial DNA in fibroblast cultures from patients with POLG1 mutations is a consequence of catalytic mutations. Hum Mol Genet 17, 2496-506
Minczuk M, Papworth MA, Miller JC, Murphy MP & Klug A (2008) Development of a single-chain, quasi-dimeric zinc-finger nuclease for the selective degradation of mutated human mitochondrial DNA. Nucleic Acids Res 36, 3926-38
Azzu V, Affourtit C, Breen EP, Parker N & Brand MD (2008) Dynamic regulation of uncoupling protein 2 content in INS-1E insulinoma cells. Biochim Biophys Acta 1777, 1378-83

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