Publications

Found 437 results
Filters: Keyword is Mitochondria  [Clear All Filters]
2008
Harper M-E, Green K & Brand MD (2008) The efficiency of cellular energy transduction and its implications for obesity. Annu Rev Nutr 28, 13-33
Ghezzi D, Saada A, D'Adamo P, Fernandez-Vizarra E, Gasparini P, Tiranti V, Elpeleg O & Zeviani M (2008) FASTKD2 nonsense mutation in an infantile mitochondrial encephalomyopathy associated with cytochrome c oxidase deficiency. Am J Hum Genet 83, 415-23
Azzu V, Parker N & Brand MD (2008) High membrane potential promotes alkenal-induced mitochondrial uncoupling and influences adenine nucleotide translocase conformation. Biochem J 413, 323-32
Lowes DA, Thottakam BMV, Webster NR, Murphy MP & Galley HF (2008) The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide-peptidoglycan model of sepsis. Free Radic Biol Med 45, 1559-65
Smith RAJ, Adlam VJ, Blaikie FH, Manas A-RB, Porteous CM, James AM, Ross MF, Logan A, Cochemé HM, Trnka J, Prime TA, Abakumova I, Jones BA, Filipovska A & Murphy MP (2008) Mitochondria-targeted antioxidants in the treatment of disease. Ann N Y Acad Sci 1147, 105-11
Trnka J, Blaikie FH, Smith RAJ & Murphy MP (2008) A mitochondria-targeted nitroxide is reduced to its hydroxylamine by ubiquinol in mitochondria. Free Radic Biol Med 44, 1406-19
Tsaousis AD, Kunji ERS, Goldberg AV, Lucocq JM, Hirt RP & T Embley M (2008) A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi. Nature 453, 553-6
Poole AC, Thomas RE, Andrews LA, McBride HM, Whitworth AJ & Pallanck LJ (2008) The PINK1/Parkin pathway regulates mitochondrial morphology. Proc Natl Acad Sci U S A 105, 1638-43
Cree LM, Samuels DC, Lopes SChuva de S, Rajasimha HKarur, Wonnapinij P, Mann JR, Dahl H-HM & Chinnery PF (2008) A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes. Nat Genet 40, 249-54
Affourtit C & Brand MD (2008) On the role of uncoupling protein-2 in pancreatic beta cells. Biochim Biophys Acta 1777, 973-9
Parker N, Vidal-Puig A & Brand MD (2008) Stimulation of mitochondrial proton conductance by hydroxynonenal requires a high membrane potential. Biosci Rep 28, 83-8
Murphy MP (2008) Targeting lipophilic cations to mitochondria. Biochim Biophys Acta 1777, 1028-31
Brookes PS, Parker N, Buckingham JA, Vidal-Puig A, Halestrap AP, Gunter TE, Nicholls DG, Bernardi P, Lemasters JJ & Brand MD (2008) UCPs--unlikely calcium porters. Nat Cell Biol 10, 1235-7; author reply 1237-40
Affourtit C & Brand MD (2008) Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion. Biochem J 409, 199-204
2007
Echtay KS & Brand MD (2007) 4-hydroxy-2-nonenal and uncoupling proteins: an approach for regulation of mitochondrial ROS production. Redox Rep 12, 26-9
Ocloo A, Shabalina IG, Nedergaard J & Brand MD (2007) Cold-induced alterations of phospholipid fatty acyl composition in brown adipose tissue mitochondria are independent of uncoupling protein-1. Am J Physiol Regul Integr Comp Physiol 293, R1086-93
Alberio S, Mineri R, Tiranti V & Zeviani M (2007) Depletion of mtDNA: syndromes and genes. Mitochondrion 7, 6-12
Cappello AR, Miniero DV, Curcio R, Ludovico A, Daddabbo L, Stipani I, Robinson AJ, Kunji ERS & Palmieri F (2007) Functional and structural role of amino acid residues in the odd-numbered transmembrane alpha-helices of the bovine mitochondrial oxoglutarate carrier. J Mol Biol 369, 400-12
Gledhill JR, Montgomery MG, Leslie AGW & Walker JE (2007) How the regulatory protein, IF(1), inhibits F(1)-ATPase from bovine mitochondria. Proc Natl Acad Sci U S A 104, 15671-6
Floyd S, Favre C, Lasorsa FM, Leahy M, Trigiante G, Stroebel P, Marx A, Loughran G, O'Callaghan K, Marobbio CMT, Slotboom DJ, Kunji ERS, Palmieri F & O'Connor R (2007) The insulin-like growth factor-I-mTOR signaling pathway induces the mitochondrial pyrimidine nucleotide carrier to promote cell growth. Mol Biol Cell 18, 3545-55
Holt IJ, He J, Mao C-C, Boyd-Kirkup JD, Martinsson P, Sembongi H, Reyes A & Spelbrink JN (2007) Mammalian mitochondrial nucleoids: organizing an independently minded genome. Mitochondrion 7, 311-21
Monné M, Robinson AJ, Boes C, Harbour ME, Fearnley IM & Kunji ERS (2007) The mimivirus genome encodes a mitochondrial carrier that transports dATP and dTTP. J Virol 81, 3181-6
Zeviani M & Carelli V (2007) Mitochondrial disorders. Curr Opin Neurol 20, 564-71
Rasola A & Bernardi P (2007) The mitochondrial permeability transition pore and its involvement in cell death and in disease pathogenesis. Apoptosis 12, 815-33
Cochemé HM, Kelso GF, James AM, Ross MF, Trnka J, Mahendiran T, Asin-Cayuela J, Blaikie FH, Manas A-RB, Porteous CM, Adlam VJ, Smith RAJ & Murphy MP (2007) Mitochondrial targeting of quinones: therapeutic implications. Mitochondrion 7 Suppl, S94-102

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