The results of a research project entitled, “Bottom-Up Construction of a Minimal System for Cellular Respiration and Energy Regeneration” have been published in ACS Synthetic Biology.
We are excited to share the news that Professors Mike Murphy (MBU, Cambridge) and Richard Hartley (Glasgow) have been awarded a Wellcome Trust Joint Investigator Award of £1.6 milion for a research project entitled, ‘Exploring mitochondrial metabolism in health and disease using targeted biological chemistry’.
In a collaborative research study with the NIHR BioResource and Genomics England published in Nature Communications, Wei Wei and Patrick Chinnery explain how large rare or unique nuclear-mitochondrial DNA segments (mega-NUMTs) can resemble paternally inherited mitochondrial DNA (mtDNA), and find no evidence of paternal transmission of mtDNA by studying whole genome sequences in 33,105 humans.
New discovery uncovers the complex dance of mitochondria, the cellular power plant.
On 2 March 2020, Alex Whitworth participated in a three-day workshop on the “Role of Drosophila in Biomedical Research”.
The 7th Annual Sir John Walker Lecture, ‘Regulation of Growth and Metabolism’, was delivered on Thursday, 30 May 2019, by David Sabatini, MD, PhD.
Professor Sabatini is a member of the Whitehead Institute and Professor of Biology at the Massachusetts Institute of Technology (MIT). He studies the pathways that regulate growth and metabolism and how they are deregulated in diseases like cancer and diabetes.
Results of a collaborative research study involving MBU scientists, "Germline selection shapes human mitochondrial DNA diversity", published in Science today suggest that changes in human mitochondrial DNA are shaped by our nuclear DNA.
University of Cambridge press release
On 7 May 2019, Nobel Laureate Professor Sir John Walker FRS, FMedSci was presented with the University of Helsinki Silver Medal, the University's highest award, in recognition of his contributions to bioenergetics and structural biology and for advising the University's Institute of Biotechnology, as a member of its Advisory Board for nearly twenty years from 1999 to 2018.
The Unit is delighted to announce that Judy Hirst and Mike Murphy have been elected Fellows of the Academy of Medical Sciences.
Fellows are elected based on their outstanding contributions to advancing medical science, cutting edge research discoveries, and translating developments into benefits for patients and wider society.
A study published today in Cell Reports led by Dr Alex Whitworth’s Mitochondrial Neurodegeneration group, in collaboration with scientists from the University of Padova, report the generation of a comprehensive toolkit for analysing the mitochondrial calcium uniporter in Drosophila.
