Featured articles

Atomic resolution cryoEM structures of mammalian respiratory complex I

Researchers at the MRC Mitochondrial Biology Unit, led by Dr Judy Hirst, have used cryoEM to determine structures of mammalian respiratory complex I at atomic resolution - sufficient to see how individual amino acid sidechains change position between two different states of the enzyme.

Tenured Professorships for Judy Hirst and Mike Murphy

The General Board of the Faculties of the University of Cambridge has recommended that, with effect from 1 October 2018, Professorships be established for Drs Judy Hirst (assigned to the Department of Clinical Neurosciences) and Mike Murphy (assigned to the Department of Medicine).


How incurable mitochondrial diseases strike previously unaffected families

Researchers have shown for the first time how children can inherit a severe – potentially fatal – mitochondrial disease from a healthy mother.

The study, led by researchers from the MRC Mitochondrial Biology Unit at the University of Cambridge, reveals that healthy people harbour mutations in their mitochondrial DNA and explains how cases of severe mitochondrial disease can appear unexpectedly in previously unaffected families.