Featured articles

MRC MBU Video Series: "Life at the MRC MBU"

The MBU is pleased to announce that two videos in the series, "Life at the MRC MBU" are now live on our website.

Life at the MRC MBU is aimed at an audience of potential MBU members, whether they be scientists wishing to join our research projects or support staff seeking background information on our activities.  This video showcases the many scientific and social aspects of life in the MBU "family".

MRC MBU scientists involved in new discovery in the fight against Motor Neurone Disease

A new target to fight Motor Neurone Disease (MND) using gene therapy has been uncovered by neuroscientists at the University of Sheffield, in collaboration with scientists in Cambridge, UCL and Ohio.

Alex Whitworth, leader of the MRC MBU's Mitochondrial Neurodegeneration research group, co-directed this research, which opens up a new field for potential therapies for the most common genetic cause of MND.

The research was funded by the MND Association.

MBU scientists secure funding for research on Pearson Syndrome

Michal Minczuk, leader of the MRC MBU’s Mitochondrial Genetics research group and his postdoctoral colleague, Payam Gammage, have been awarded $100,000 by The Champ Foundation to carry out research into Pearson Syndrome – a multi-system disease caused by a deletion in mitochondrial DNA.

The funding has been awarded for two years and the research proposal is one of two projects to be selected from a shortlist of five worldwide.

Scientific Movies for the MRC MBU

The MRC MBU is delighted to share our new series of scientific movies, which visualise our research and explain some of the mechanisms and processes that take place within our cells:

Complex I: Electron Transfer - Labelling
Complex I: Subunits
Inside the Human Cell
Fission & Fusion
Mitochondrial Dynamics
Mitochondrial Matrix: ATP

Life at the MRC MBU - Students Perspectives

The MRC MBU is pleased to announce that its first video in the series, "Life at the MRC MBU" is now live on our website.

This video, filmed and produced by Cambridge TV, is aimed at an audience of students up to the end of secondary school. It contains contributions from current MBU PhD students and postdoctoral scientists who have graduated through the University of Cambridge, having carried out their graduate research in the Unit.

Mike Murphy talks to The Royal Society about the chemical biology of mitochondria

Mike Murphy, Group Leader/PI of the MRC MBU, organised a Royal Society scientific discussion meeting entitled 'Chemical biology approaches to assessing and modulating mitochondria', bringing together biologists, chemists and clinicians to discuss recent developments in the field.

Select talks were subsequently published in an issue of Interface Focus as a record of work to date and as a stimulus to future work. The Royal Society spoke to Mike about his work, the meeting and how the field could progress.

Medical Research Council Mitochondrial Biology Unit Transfers into the University of Cambridge

The Medical Research Council (MRC) and the University of Cambridge are delighted to announce that, today, the MRC Mitochondrial Biology Unit (MRC MBU) has transferred into the University and is now a University Unit department within the School of Clinical Medicine.

The MRC MBU has retained its current research facilities in the Wellcome Trust/MRC Building on the Cambridge Biomedical Campus and its staff members are now employees of the University.

Mike Murphy and his group collaborate towards a major breakthrough in inflammation research

Mitochondria are repurposed from energy generators to drivers of inflammation.

A collaboration involving nine institutions, including the MRC MBU, has led to a report in Cell on a significant breakthrough in our understanding of inflammation, a key process in our bodies which occurs during infection and injury, but which can go awry in a range of inflammatory diseases.

The lead authors of this report are based at Trinity College Dublin.

Judy Hirst - publication in 'Nature'

In collaboration with Vinothkumar at The MRC Laboratory of Molecular Biology in Cambridge we report the structure of respiratory complex I, one of the largest and most complicated enzymes in the mammalian cell.

Link to publication in Nature

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