Mike Murphy - Publications

2018

• Rossman MJ, Santos-Parker JR, Steward CAC, Bispham NZ, Cuevas LM, Rosenberg HL, Woodward KA, Chonchol M, Gioscia-Ryan RA, Murphy MP & Seals DR (2018) Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults. Hypertension
• Fazakerley DJ, Minard AY, Krycer JR, Thomas KC, Stöckli J, Harney DJ, Burchfield JG, Maghzal GJ, Caldwell ST, Hartley RC, Stocker R, Murphy MP & James DE (2018) Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation. J Biol Chem 293, 7315-7328
• Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sévin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP & O'Neill LA (2018) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature 556, 113-117
• Secinaro MA, Fortner KA, Dienz O, Logan A, Murphy MP, Anathy V, Boyson JE & Budd RC (2018) Glycolysis promotes caspase-3 activation in lipid rafts in T cells. Cell Death Dis 9, 62
• Xi Y, Feng D, Tao K, Wang R, Shi Y, Qin H, Murphy MP, Yang Q & Zhao G (2018) MitoQ protects dopaminergic neurons in a 6-OHDA induced PD model by enhancing Mfn2-dependent mitochondrial fusion via activation of PGC-1α. Biochim Biophys Acta
• Foote K, Reinhold J, Yu EPK, Figg NL, Finigan A, Murphy MP & Bennett MR (2018) Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice. Aging Cell, e12773
• Chong KLeong, Chalmers BA, Cullen JK, Kaur A, Kolanowski JL, Morrow BJ, Fairfull-Smith KE, Lavin MJ, Barnett NL, New EJ, Murphy MP & Bottle SE (2018) Pro-fluorescent mitochondria-targeted real-time responsive redox probes synthesised from carboxy isoindoline nitroxides: Sensitive probes of mitochondrial redox status in cells. Free Radic Biol Med
• Peruzzotti-Jametti L, Bernstock JD, Vicario N, Costa ASH, Kwok CKeong, Leonardi T, Booty LM, Bicci I, Balzarotti B, Volpe G, Mallucci G, Manferrari G, Donegà M, Iraci N, Braga A, Hallenbeck JM, Murphy MP, Edenhofer F, Frezza C & Pluchino S (2018) Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation. Cell Stem Cell 22, 355-368.e13
• Martin JL, Gruszczyk AV, Beach TE, Murphy MP & Saeb-Parsy K (2018) Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury. Pediatr Nephrol
• Sidlauskaite E, Gibson JW, Megson IL, Whitfield PD, Tovmasyan A, Batinic-Haberle I, Murphy MP, Moult PR & Cobley JN (2018) Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning. Redox Biol 16, 344-351