Mike Murphy - Publications

2018

• Pell VR, Spiroski A-M, Mulvey J, Burger N, Costa ASH, Logan A, Gruszczyk AV, Rosa T, James AM, Frezza C, Murphy MP & Krieg T (2018) Ischemic preconditioning protects against cardiac ischemia reperfusion injury without affecting succinate accumulation or oxidation. J Mol Cell Cardiol 123, 88-91
• James AM, Smith AC, Smith CL, Robinson AJ & Murphy MP (2018) Proximal Cysteines that Enhance Lysine N-Acetylation of Cytosolic Proteins in Mice Are Less Conserved in Longer-Living Species. Cell Rep 24, 1445-1455
• Kim J-H, Choi TGyu, Park S, Yun HRok, Nguyen NNgo Yen, Jo YHwa, Jang M, Kim J, Kim J, Kang I, Ha J, Murphy MP, Tang DG & Kim SSoo (2018) Mitochondrial ROS-derived PTEN oxidation activates PI3K pathway for mTOR-induced myogenic autophagy. Cell Death Differ
• Stovell MG, Mada MO, Helmy A, T Carpenter A, Thelin EP, Yan J-L, Guilfoyle MR, Jalloh I, Howe DJ, Grice P, Mason A, Giorgi-Coll S, Gallagher CN, Murphy MP, Menon DK, Hutchinson PJ & Carpenter KLH (2018) The effect of succinate on brain NADH/NAD redox state and high energy phosphate metabolism in acute traumatic brain injury. Sci Rep 8, 11140
• Robb EL, Hall AR, Prime TA, Eaton S, Szibor M, Viscomi C, James AM & Murphy MP (2018) Control of mitochondrial superoxide production by reverse electron transport at complex I. J Biol Chem 293, 9869-9879
• Rossman MJ, Santos-Parker JR, Steward CAC, Bispham NZ, Cuevas LM, Rosenberg HL, Woodward KA, Chonchol M, Gioscia-Ryan RA, Murphy MP & Seals DR (2018) Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults. Hypertension
• Fazakerley DJ, Minard AY, Krycer JR, Thomas KC, Stöckli J, Harney DJ, Burchfield JG, Maghzal GJ, Caldwell ST, Hartley RC, Stocker R, Murphy MP & James DE (2018) Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation. J Biol Chem 293, 7315-7328
• Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sévin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP & O'Neill LA (2018) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature 556, 113-117
• Secinaro MA, Fortner KA, Dienz O, Logan A, Murphy MP, Anathy V, Boyson JE & Budd RC (2018) Glycolysis promotes caspase-3 activation in lipid rafts in T cells. Cell Death Dis 9, 62
• Gioscia-Ryan RA, Battson ML, Cuevas LM, Eng JS, Murphy MP & Seals DR (2018) Mitochondria-targeted antioxidant therapy with MitoQ ameliorates aortic stiffening in old mice. J Appl Physiol (1985) 124, 1194-1202