MELAS syndrome: characteristic migrainous and epileptic features and maternal transmission.

TitleMELAS syndrome: characteristic migrainous and epileptic features and maternal transmission.
Publication TypeJournal Article
Year of Publication1988
AuthorsMontagna, P, Gallassi, R, Medori, R, Govoni, E, Zeviani, M, Di Mauro, S, Lugaresi, E, Andermann, F
JournalNeurology
Volume38
Issue5
Pagination751-4
Date Published1988 May
ISSN0028-3878
KeywordsAdolescent, Biopsy, Epilepsy, Female, Humans, Male, Middle Aged, Migraine Disorders, Mitochondria, Muscle, Muscles, Recurrence, Status Epilepticus, Syndrome, Vomiting
Abstract

Severe prolonged migrainous symptoms and prolonged partial status epilepticus are characteristic features of the MELAS syndrome (mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes). Maternal transmission previously found in myoclonus epilepsy and ragged-red fibers (MERRF), another mitochondrial disease, is suggested in this disorder as well.

DOI10.1212/wnl.38.5.751
Alternate JournalNeurology
Citation Key10.1212/wnl.38.5.751
PubMed ID3362373