Overview of protein glutathionylation.

TitleOverview of protein glutathionylation.
Publication TypeJournal Article
Year of Publication2006
AuthorsFilipovska, A, Murphy, MP
JournalCurr Protoc Toxicol
VolumeChapter 6
Date Published2006 Jun
KeywordsGlutaredoxins, Glutathione, Nitric Oxide, Oxidation-Reduction, Proteins, Sulfhydryl Compounds, Thioredoxins

Many proteins contain free thiols that can be modified by the reversible formation of mixed disulfides with glutathione. Protein glutathionylation is of significance for defense against oxidative damage and in redox signaling. Here we outline the mechanisms and possible significance of protein glutathionylation.

Alternate JournalCurr Protoc Toxicol
Citation Key10.1002/0471140856.tx0610s28
PubMed ID23045136