MitoMiner: a data warehouse for mitochondrial proteomics data.

TitleMitoMiner: a data warehouse for mitochondrial proteomics data.
Publication TypeJournal Article
Year of Publication2012
AuthorsSmith, AC, Blackshaw, JA, Robinson, AJ
JournalNucleic Acids Res
IssueDatabase issue
Date Published2012 Jan
KeywordsAnimals, Cattle, Databases, Protein, Green Fluorescent Proteins, Humans, Mass Spectrometry, Mice, Mitochondrial Proteins, Proteomics, Rats, User-Computer Interface

MitoMiner ( is a data warehouse for the storage and analysis of mitochondrial proteomics data gathered from publications of mass spectrometry and green fluorescent protein tagging studies. In MitoMiner, these data are integrated with data from UniProt, Gene Ontology, Online Mendelian Inheritance in Man, HomoloGene, Kyoto Encyclopaedia of Genes and Genomes and PubMed. The latest release of MitoMiner stores proteomics data sets from 46 studies covering 11 different species from eumetazoa, viridiplantae, fungi and protista. MitoMiner is implemented by using the open source InterMine data warehouse system, which provides a user interface allowing users to upload data for analysis, personal accounts to store queries and results and enables queries of any data in the data model. MitoMiner also provides lists of proteins for use in analyses, including the new MitoMiner mitochondrial proteome reference sets that specify proteins with substantial experimental evidence for mitochondrial localization. As further mitochondrial proteomics data sets from normal and diseased tissue are published, MitoMiner can be used to characterize the variability of the mitochondrial proteome between tissues and investigate how changes in the proteome may contribute to mitochondrial dysfunction and mitochondrial-associated diseases such as cancer, neurodegenerative diseases, obesity, diabetes, heart failure and the ageing process.

Alternate JournalNucleic Acids Res.
Citation Key10.1093/nar/gkr1101
PubMed ID22121219
PubMed Central IDPMC3245170
Grant ListMC_U105674181 / / Medical Research Council / United Kingdom