Molecular basis for inherited mitochondrial disease
Understanding the molecular mechanism of complex I and its roles in human disease.
Understanding transport processes in mitochondria
Discovering the genetic links between mitochondrial dysfunction and human disease
Targeting therapeutic and probe molecules to mitochondria, mitochondrial radical production and redox signalling
Understanding mitochondria using computer modelling.
Understanding the molecular mechanism of how ATP is made.
The structure and function of bacterial respiratory complex I.