Professor Nicholas Wood

'Parkinson’s disease: is it all mitochondrial?'

Wed, 9 May, 2012
3:00 pm
Lecture Theatre, Level 7

There has been tremendous progress in our molecular characterisation of Parkinson’s disease in the last decades. One of the striking core features that has emerged is the central role played by mitochondrial dysfunction. It is principally implicated in the autosomal recessive genes especially PINK1, PARKIN and the newly described FPX07. However there is tempting and suggestive evidence that some of the other genes, including alpha synuclein, may well have pathogenic involvement to the mitochondrial pathway. The lessons learned from genetics through to mitochondrial biology and dysfunction will be discussed.