science festival

Cambridge Science Festival 2014

On 23 March 2014 at the Cambridge Science Festival, scientists from the MRC Mitochondrial Biology Unit (MBU) used posters, movies and computer games, created by Henry Harling, to demonstrate how mitochondrial dysfunction leads to illness and ageing.

Visitors were given an explanation of heteroplasmy - when an individual has mutant as well as normal mitochondrial DNA - which was demonstrated by the Heteroplasmy video game.

Cambridge Science Festival 2013

The festival this year saw the premiere of three new animations. The first animation shows all of the major organelles of the human cell, including a dynamic network of mitochondria that are involved in fusion and fission events. The basic structure of a mitochondrion with the inner and outer membrane and cristae is also explained. The second one illustrates some of the major events of energy conversion at the mitochondrial inner membrane, featuring isocitrate dehydrogenase, Complex I, ATP synthase, mitochondrial transport proteins, the voltage gated anion channel, and hexokinase.

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