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MRC Mitochondrial Biology Unit

 
Read more at: Study in mice shows potential for new treatment to reduce brain damage from stroke

Study in mice shows potential for new treatment to reduce brain damage from stroke

6 August 2025

Cambridge scientists have developed and tested a new drug in mice that has the potential to reduce damage to the brain following stroke – a problem that affects more than nine in 10 stroke patients. Results from a collaborative research study led by Professors Mike Murphy and Thomas Krieg , working with a mouse model...


Read more at: Aspiring Scientists Training Programme (ASTP)
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Aspiring Scientists Training Programme (ASTP)

21 July 2025

From 7-11 July 2025, the MBU participated in the Gurdon Institute's Aspiring Scientists Training Programmme . Led by St Catharine’s College and the Gurdon Institute , we collaborated with Newnham College , Sainsbury Laboratory , Cambridge Institute for Medical Research (CIMR) and Wellcome-MRC Institute of Metabolic Science...


Read more at: Mike Murphy receives the Derek Willoughby Medal from the William Harvey Research Institute at Queen Mary, University of London
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Mike Murphy receives the Derek Willoughby Medal from the William Harvey Research Institute at Queen Mary, University of London

1 July 2025

On 25 June, Mike Murphy received the Derek Willoughby Medal from the William Harvey Research Institute at Queen Mary, University of London and gave a lecture at the William Harvey Research Institute's annual research day. This medal is awarded every two years for outstanding contribution to inflammation science. Previous...


Read more at: CSAR PhD Student Award for MBU Student Lucia Luengo Gutierrez
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CSAR PhD Student Award for MBU Student Lucia Luengo Gutierrez

1 July 2025

Congratulations to Lucia Luengo Gutierrez, who has been selected for an award from the Cambridge Society for the Application of Resarch (CSAR) . The CSAR PhD Student Awards of £1,000 each, are intended to recognise outstanding research with real world application and to assist students to pursue their research or careers...


Read more at: Judy Hirst awarded European Research Council Advanced Grant
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Judy Hirst awarded European Research Council Advanced Grant

17 June 2025

Congratulations to Professor Judy Hirst , who has been awarded an Advanced Grant from the European Research Council (ERC). Judy's grant is for the energy-converting mechanism of a modular biomachine: Uniting structure and function to establish the engineering principles of respiratory complex I. Advanced Grants may be...


Read more at: MBU Postdoc receives Young Invesgator Award from SFRRE
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MBU Postdoc receives Young Invesgator Award from SFRRE

13 June 2025

The Society for Free Radical Research - Europe (SFRR-E) is dedicated to promoting interest in all aspects of research related to Free Radicals in any scientific field. At its 22nd International Biennial meeting held in Galway, Ireland in June, Alva Casey received the Society's Young Investigator Award. Alva is a...


Read more at: Abigail Giles receives The Richard J Bing Award for Young Investigators
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Abigail Giles receives The Richard J Bing Award for Young Investigators

2 June 2025

At the recent World Congress of the International Society for Heart Research , held in Japan, Abigail Giles was awarded The Richard J Bing Award for Young Investigators . Abigail studied for her PhD at the MBU, funded by the NIH Oxford-Cambridge Partnership Program, spending her time split between Cambridge and the...


Read more at: Mike Murphy elected as a member of Academia Europaea
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Mike Murphy elected as a member of Academia Europaea

19 May 2025

Congratulations to Professor Mike Murphy , who has been elected as a member of Academia Europaea : The Academy of Europe. The object of Academia Europaea is the advancement and propagation of excellence in scholarship in the humanities, law, the economic, social, and political sciences, mathematics, medicine, and all...


Read more at: Structure of the mitochondrial pyruvate carrier visualised by cryo-electron microscopy

Structure of the mitochondrial pyruvate carrier visualised by cryo-electron microscopy

18 April 2025

Fifty years since its discovery, scientists in the laboratory of Professor Edmund Kunji have finally worked out how a molecular machine found in mitochondria allows us to make the fuel we need from sugars, a process vital to all life on Earth. In collaboration with the groups of Professors Vanessa Leone at the Medical...


Read more at: Pretzel Therapeutics, an MBU spin-out company, launches Phase 1 clinical study
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Pretzel Therapeutics, an MBU spin-out company, launches Phase 1 clinical study

4 April 2025

Pretzel Therapeutics has announced the initiation of recruitment for a Phase 1 clinical study of PX578, the lead therapeutic in its bioenergetics restoration phase. The randomized, double-blind, placebo-controlled study is designed to evaluate the safety, tolerability and pharmacokinetics of single and multiple ascending...