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MRC Mitochondrial Biology Unit
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Director's Introduction
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Research Groups overview
Hirst Group
Hirst Group overview
Complex I cryoEM
Complex I mechanism
Physiological effects and mitochondrial disease models
Pharmacology & toxicology involving complex I
Chinnery Group
Kunji Group
Kunji Group overview
Calcium regulation of mitochondrial carriers
Diseases caused by mitochondrial transport proteins
Electron microscopy of mitochondrial transport proteins
Identification of mitochondrial transport proteins
Role of cardiolipin in mitochondrial carriers
Structural and functional analysis of the mitochondrial pyruvate carrier
Structures of mitochondrial transport proteins
Substrate binding and proton coupling
Transport mechanism of mitochondrial carriers
Minczuk Group
Minczuk Group overview
Mito gene expression
Mitochondrial disease
mtDNA engineering
Murphy Group
Murphy Group overview
Mitochondrial Exomarkers
Mitochondrial Therapies
Thiol Proteomics
Petkevicius Group
Petkevicius Group overview
The biology of TLCD proteins
Lipotoxicity and mitochondrial phospholipids
Prudent Group
Prudent Group overview
Mechanisms of mitochondrial dynamics
Mitochondria-organelle membrane contact sites
Mitochondrial membrane remodelling and mtDNA dynamics
Ryan Group
Ryan Group overview
Mitochondrial retrograde signalling
Transcription factor-driven metabolic reprogramming
van den Ameele Group
van den Ameele Group overview
Chromatin and Mitochondrial Disease
Neural stem cell-niche interactions in mitochondrial disease
Walker Group
Walker Group overview
ATP Synthase
Subunit composition of ATP synthase
Evolution of the structure of ATP synthase
The structure and function of ATP synthases
Dimers
Molecular animations of ATP synthase
Regulation of ATP synthases
The biogenesis and assembly of the human ATP synthase
Protein methylation
The ATP synthase and the permeability transition in mitochondria
Whitworth Group
Whitworth Group overview
Cell biology of mitochondrial homeostasis - overview
Mechanisms of mitophagy and PINK1/Parkin function
Mechanisms to handle and mitigate mtDNA mutations
Mitochondrial calcium in health and neurodegeneration
Redox biology in neurodegeneration
Regulation of RNA biology in mitochondrial and neuronal homestasis
Activation of immune signalling upon mitochondrial disruption
Integration with the Department of Clinical Neurosciences and NHS
Integration with the Department of Clinical Neurosciences and NHS overview
Associated Research Groups
Research Resources and Facilities
Research Resources and Facilities overview
MitoPhen
MitoMiner
ComPrAn
IMPI
MitoCore
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Postgraduate Studies
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What are Mitochondria
What are Mitochondria overview
Mitochondria in Biology
Mitochondria in Disease
Public Engagement
Public Engagement overview
Public Engagement Objectives
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Mitochondria and Art
MITOTrumps
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Seminars and events announcements overview
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Wellbeing and Equality overview
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MBU Postgraduate Student Society
MBU Postdoctoral Society
MBU Postdoctoral Society overview
Postdocs
Postdocs overview
Stephen Burr
Mariangela Dionysopoulou
Dnyanesh Dubal
Federica De Lazzari
Michele Frison
Bosco Jose
Denis Lacabanne
Leonor Miller-Fleming
Stavroula Petridi
Hiran Ambelal Prag
Alvaro Sanchez-Martinez
Pedro Silva Pinheiro
Alice Sowton
Sotiria Tavoulari
Lindsey Van Haute
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MRC Mitochondrial Biology Unit
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