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MRC Mitochondrial Biology Unit

 
Read more at: Batten Disease Global Research Initiative Grant for Kasparas Petkevicius

Batten Disease Global Research Initiative Grant for Kasparas Petkevicius

19 March 2025

Congratulations to Kasparas Petkevicius , who has been awarded a grant of $50,000 from the Batten Disease Global Research Initiative , which will fund a research project “Exploring the efficacy of bis(monoacylglycero)phosphate synthesis pathway intermediates in treating CLN8 Batten disease in preclinical models.” Batten...


Read more at: Mitochondrial superoxide regulates pro-inflammatory macrophages

Mitochondrial superoxide regulates pro-inflammatory macrophages

6 March 2025

Pro-inflammatory macrophages produce mitochondria-derived reactive oxygen species (mtROS) such as superoxide, but it is not understood how it is produced or how it affects macrophage effector functions. Published in Nature Metabolism , results of a study led by Professor Mike Murphy , who that mitochondrial superoxide is...


Read more at: New research uncovers a novel family of phospholipid remodelling enzymes

New research uncovers a novel family of phospholipid remodelling enzymes

6 March 2025

Phospholipids, the fundamental building blocks of cellular membranes, are continuously remodelled to ensure membrane integrity and function. A new study from the lab of Dr Kasparas Petkevicius at the MRC Mitochondrial Biology Unit, published in Science Advances , demonstrates that TRAM-LAG1-CLN8 (TLC) family proteins...


Read more at: ISAC/M 2025: Inspiring Scientists at the Cambridge Institute for Medical Research and the MRC Mitochondrial Biology Unit

ISAC/M 2025: Inspiring Scientists at the Cambridge Institute for Medical Research and the MRC Mitochondrial Biology Unit

27 February 2025

This annual free, widening participation programme for Cambridgeshire-based Year 12 students (16+) took place from 18-21 February (half-term) at the Cambridge Institute for Medical Research (CIMR) and MRC Mitochondrial Biology Unit (MBU), in association with St Catharine's College , Cambridge. Ten students were involved in...


Read more at: Cambridge signs sustainable research agreement
Trees

Cambridge signs sustainable research agreement

14 February 2025

The University of Cambridge has become a signatory to the ground-breaking Concordat for the Environmental Sustainability of Research and Innovation Practice , joining 70 signatories and supporting organisations (as of 13 February 2025). "Not only is the Concordat a very welcome initiative to bring the sector together and...


Read more at: Research Culture Celebration 2024 - Dylan Ryan

Research Culture Celebration 2024 - Dylan Ryan

7 October 2024

Congratulations to Dylan Ryan , who was nominated for the Research Culture Celebration 2024 in recognition of his contribution to positive Research Culture among his colleagues. The University celebrated all nominees alongside colleagues who nominated them, friends and senior leadership on Monday 30 September at a party at...


Read more at: Research by the Whitworth group has been highlighted in the Life Science Alliance Neuroscience Collection 2024

Research by the Whitworth group has been highlighted in the Life Science Alliance Neuroscience Collection 2024

3 October 2024

Recent research from the group has been selectively highlighted in Life Science Alliance’s Neuroscience Collection 2024 (a "special collection of articles recently published in LSA highlighting some of the latest advances in neuroscience”), and will also be featured in a special magazine that LSA are distributing at SfN...


Read more at: World Mitochondrial Disease Week: 16-22 September
World Mitochondrial Disease Week 2024

World Mitochondrial Disease Week: 16-22 September

16 September 2024

The annual World Mitochondrial Disease Week (WMDW) is 16-22 September this year. World Mitochondrial Disease Week raises awareness about mitochondrial diseases (mito). It aims to improve the lives of people affected by mito and to increase awareness among doctors and the general public. As researchers in mitochondrial...


Read more at: New research uncovers a mitochondrial quality control pathway for maintaining adequate mtDNA levels within cells

New research uncovers a mitochondrial quality control pathway for maintaining adequate mtDNA levels within cells

7 June 2024

Mitochondria are small organelles within our cells that contain their own genetic material, known as mitochondrial DNA (mtDNA). mtDNA encodes 13 core subunits of the different complexes of the respiratory chain and is essential to sustain cellular metabolism and life. Only two copies of nuclear DNA (nDNA) are required to...


Read more at: Patrick Chinnery elected as a Fellow of the Royal Society

Patrick Chinnery elected as a Fellow of the Royal Society

16 May 2024

Congratulations to Professor Patrick Chinnery , who has been elected as a Fellow of the Royal Society in recognition of his substantial contribution to the advancement of science. Nine of the Royal Society’s newly elected Fellows are from the University of Cambridge. University of Cambridge press release