skip to content

MRC Mitochondrial Biology Unit

 

Judy Hirst

Mitochondrial complex I: An intricate energy-converting machine, a cornerstone of mitochondrial metabolism, and a locus of mitochondrial dysfunction and disease

 

 

 

 

 

Patrick Chinnery

Mitochondrial Genomics: Inherited and acquired variants of nuclear and mitochondrial DNA in human health and disease

 

 

 

 

 

Edmund Kunji

Mitochondrial transport proteins: Highly dynamic integral membrane proteins required for the translocation of metabolites and cofactors, key to the function of the mitochondrion

 

 

 

 

 

Michal Minczuk

Mitochondrial genetics: Mitochondrial genome engineering to unravel the genetic links between mitochondrial gene regulation and human disease for future therapies

 

 

 

 

 

Michael Murphy

Mitochondrial ROS production: Central to many pathologies and signalling processes and a key target for novel therapies

 

 

 

 

 

Julien Prudent

Mitochondrial cell biology: Mitochondrial dynamics and membrane contact sites as key regulators of cell fate decisions

 

 

 

 

 

Jelle van den Ameele

Mitochondria in development: Neural stem cell-niche interactions that protect the developing and aging brain against mitochondrial dysfunction

 

 

 

 

 

John Walker

Mitochondrial ATP synthase: cellular power generator, determinant of mitochondrial cristae formation, a site linked to human diseases

 

 

 

 

 

Alex Whitworth

Mitochondria in neurodegeneration: Investigating the role of mitochondria and metabolism in the cause and therapeutic targeting of neurodegenerative diseases