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MRC Mitochondrial Biology Unit

 

The strategic mission of the MBU is to understand mitochondrial biology in health and disease, and to exploit this understanding to develop new therapies and improve human health.

 


 

Read more at: Research study supports the view that ATP synthase arose via independent evolution of its three constituent structural modules
Figure 7

Research study supports the view that ATP synthase arose via independent evolution of its three constituent structural modules

30 June 2026

Human ATP synthase is a molecular rotary machine built from twenty-eight subunits of seventeen kinds, two encoded in mitochondrial DNA, fifteen in the nucleus. A team led by John Walker has provided further evidence that assembly proceeds via construction of its three constituent modules, the F 1 -module, the peripheral...


Read more at: MitoLiPox - a targeted mass spectrometry probe to assess mitochondrial lipid peroxidation
Shinpei Uno

MitoLiPox - a targeted mass spectrometry probe to assess mitochondrial lipid peroxidation

30 June 2026

Mitochondrial lipid peroxidation is central to cell death by ferroptosis in many pathologies. However, measuring this process is challenging. As part of a Wellcome Trust - funded collaboration led by Mike Murphy at the MBU and Richard Hartley at Glasgow this has been addressed by developing a mitochondria-targeted probe...


Read more at: Michal Minczuk elected a Foreign Member of the Polish Academy of Sciences

Michal Minczuk elected a Foreign Member of the Polish Academy of Sciences

29 June 2026

Congratulations to Michal Minczuk , who has been elected a Foreign Member of the Polish Academy of Sciences . This distinction is awarded to outstanding scholars from outside Poland whose scientific achievements are of significant importance for the development of global science and international cooperation. The election...


Read more at: Mike Murphy delivers the Keith Reimer Distinguished Lecture of the ISHR

Mike Murphy delivers the Keith Reimer Distinguished Lecture of the ISHR

26 June 2026

On 22 June, Mike Murphy delivered the Keith Reimer Distinguished Lecture of the International Society for Heart Research (ISHR) at the XXXIX Annual meeting of the Society’s European Section, held in Birmingham. Dr Keith Reimer was a leader in the study of myocardial ischemia, and for 25 years moved that field forward in...


Read more at: Alex Whitworth co-leads the Fly-NeuroCan 2026 training workshop in Ibadan, Nigeria

Alex Whitworth co-leads the Fly-NeuroCan 2026 training workshop in Ibadan, Nigeria

26 June 2026

Alex Whitworth recently had an amazing and inspiring time co-leading the Fly-NeuroCan 2026 training workshop in Ibadan, Nigeria, with Professor Abolaji Amos and his dedicated team at the Drosophila Research and Training Centre . Alex persuaded PhD student Tom Wight to experience science in Western Africa. Further coverage...


Read more at: John Walker admitted as an Honorary Member of L'Istituto Veneto

John Walker admitted as an Honorary Member of L'Istituto Veneto

26 June 2026

On 7 June, at a ceremony held in the Doges' Palace, John Walker was admitted as an Honorary Member of L’ Istituto Veneto, the Venetian Academy of Science, Arts and Letters. The Academy was founded in 1809 by Napoleon. Congratulations John!


Read more at: Cambridge Festival Biomedical Campus Day

Cambridge Festival Biomedical Campus Day

25 March 2026

On 21 March, members of the MBU enjoyed a very successful event at the Cambridge Festival Biomedical Campus Day, which was hosted at the Cambridge Academy for Science and Technology . Through the use of games and activities that are aimed audiences of all ages, we had a very enjoyable time explaining our research to our...


Read more at: Professor Nils-Göran Larsson to deliver the 10th Annual Sir John Walker Lecture

Professor Nils-Göran Larsson to deliver the 10th Annual Sir John Walker Lecture

6 February 2026