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MRC Mitochondrial Biology Unit

 

Education

1984-1997 PhD in Biochemistry, Peterhouse, University of Cambridge
1980-1984  BA in Chemistry, Trinity College, Dublin
1975-1980 Coolmine Community School, Dublin

Professional Career

2001-present Programme Leader, MRC Mitochondrial Biology Unit, University of Cambridge, UK
2018-present Professosr of Mitochondrial Redox Biology, University of Cambridge
1992-2001 Lecturer/Senior Lecturer/Associate Professor, Biochemistry Department, University of Otago, New Zealand
1990-1992 Lecturer, Biochemistry Department, Trinity College, Dublin, Ireland
1989 Teacher with Voluntary Services Overseas (London) in Zimbabwe
1988 Associate Research Scientist, Columbia University College of Physicians and Surgeons, New York

Awards and Honours

2020   Nanyang-SNIC Distinguished Lectureship, Nanyang Technological University, Singapore
2019  Joseph Larner Memorial Lecturer in Pharmacology, University of Virginia, USA
2019  Fellow of the Academy of Medical Sciences (FMedSci)
2018-present  Personal Professorship, University of Cambridge
2018 The 2018 Basic Science Lecturer, Society for Free Radical Research-Europe
2017 The 2017 Gopal Singhal Lecturer, Chemistry Department, Wayne State University, USA
2016-present   Honorary Research Professor, Chemistry Department, University of Otago, NZ
2016-present  Wellcome Trust Investigator
2016 Keilin Memorial Lecture and Medal
2012 Honorary Fellow of the Royal Society of New Zealand (Hon FRSNZ)
2008 The Nathan O. Kaplan Lecturer, University of California, San Diego
2001-present  Honorary Fellow, Depts of Chemistry and Biochemistry, University of Otago
2000 Research Medal of the New Zealand Association of Scientists
2000 Applied Biosystems Medal, NZ Society of Biochemistry and Molecular Biology
1984-1987 Open Research Studentship, Peterhouse, University of Cambridge
1984  Cocker Medal for Experimental Chemistry
1982-1987  Foundation Scholarship
1982 C Walter Jones Prize in Organic Chemistry 

Current Journal Editorial Boards

2016-present  Cell Metabolism: Editorial board
2013-present Redox Biology: Editorial board
2013-present Redox Report: Editorial board
2012-present  Free Radical Biology and Medicine: Editorial board
2010-present  Free Radical Research: Editorial board

Advisory Boards

2020-present  Imperial College London EPSRC-funded programme “Health assessment across biological length scales for personal pollution exposure and its mitigation (INHALE)”: Scientific Advisory Board
 2019-present University of Freiburg, Germany, Centre for Integrative Biological Signalling Studies: Scientific Advisory Board
2017-present   EU H2020 FET-Open program (Future and Emerging Technologies) - Lumiblast: Expert monitor
2001-present  Antipodean Pharmaceuticals, New Zealand: Scientific advisory board

Patents

Mitochondria-targeted dicarbonyl sequestering compounds, Michael P. Murphy, Robin A. J. Smith and Richard C. Hartley, United States Patent US 9,963,474
Mitochondrially targeted antioxidants, Michael P. Murphy and Robin A. J. Smith, United States Patent US 6,331,532.
Mitochondrially targeted antioxidants, Michael P. Murphy and Robin A. J. Smith, United States Patent US 6,984,636.
Mitochondrially targeted antioxidants, Michael P. Murphy and Robin A. J. Smith, Australian Patent AU 763179.
Mitochondrially targeted antioxidants, Michael P. Murphy and Robin A. J. Smith, New Zealand Patent NZ 505352.
Mitochondrially targeted antioxidants, Michael P. Murphy and Robin A. J. Smith, United States Patent US 7,109,189.
Mitochondrially targeted antioxidants, Michael P. Murphy and Robin A. J. Smith, New Zealand Patent NZ 538371.
Triphenylphosphonium thionitrite nitric oxide donors, Michael P. Murphy and Robin A. J. Smith European Patent EP2066680.
Triphenylphosphonium thionitrite nitric oxide donors, Michael P. Murphy and Robin A. J. Smith. Canadian Patent CA 2664744.
Triphenylphosphonium thionitrite nitric oxide donors, Michael P. Murphy and Robin A. J. Smith. United States Patent US 12/732,909.
Mitoquinone derivatives used as mitochondrially targeted antioxidants, Michael P. Murphy and Robin A. J Smith, United States patent US 7,888,334.
Mitochondrially targeted antioxidants, Michael P Murphy and Robin A. J Smith, Canadian Patent  CA 2311318

Lab Alumni

Helena Cocheme - MRC Clinical Sciences Centre, London, UK

Jan Trnka - Charles University, Prague, Czech Republic

Christina Dahm - Aarhus University, Aarhus, Denmark

Aleksandra Filipovska - Harry Perkins Institute of Medical Research, Perth, Australia

Thomas Hurd - University of Toronto, Toronto, Canada

Edward Chouchani - Harvard Medical School and Dana-Farber Cancer Institute, Boston, USA