Submitted by Penny Peck on Wed, 06/08/2025 - 00:00
Cambridge scientists have developed and tested a new drug in mice that has the potential to reduce damage to the brain following stroke – a problem that affects more than nine in 10 stroke patients.
Results from a collaborative research study led by Professors Mike Murphy and Thomas Krieg, working with a mouse model designed by Dr Jordan Lee (Murphy Group), have been published in Cardiovascular Research.
Further details can be found in the University of Cambridge Press Release.
Publication Reference:
Lee JJ, Prag HA, Chary K, Abe J, Uno S, Sorby-Adams A, Shun Yu C, Sauchanka O, Mottahedin A, Kaggie JD, Gallagher FA, Murphy MP, Krieg T. Local arterial administration of acidified malonate as an adjunct therapy to mechanical thrombectomy in ischaemic stroke.
Cardiovasc Res. 2025 Jun 27:cvaf118. doi: 10.1093/cvr/cvaf118. Epub ahead of print. PMID: 40577592.