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Mitochondrial DNA migrate into the nuclear genome

5 October 2022

Mitochondria are tiny ‘organelles’ that sit within our cells, where they act like batteries, providing energy in the form of the molecule ATP to power the cells. Each mitochondrion has its own DNA – mitochondrial DNA – that is distinct to the rest of the human genome, which is comprised of nuclear DNA. The results of a...

Pretzel Therapeutics Launches as a new Start Up

4 October 2022

The MBU Mitochondrial Genetics Programme Leader Michal Minczuk , with two other experts in mitochondrial gene regulation, Claes Gustafsson from the University of Gothenburg and Nils-Göran Larsson from Karolinska Institutet co-founded a new start-up company Pretzel Therapeutics . Launched last month, Pretzel Therapeutics is...

Career Development Opportunites for Experienced Postdocs!

20 September 2022

Three unique “Springboard to Independence” positions are available at the Mitochondrial Biology Unit. We are looking for candidates who : want to develop an independent career in mitochondrial research have research interests that fit in with the MBU. We offer : up to four years' funding with an addociated postdoc/...

Baking it Green for World Mitochondrial Disease Week

20 September 2022

World Mitochondrial Disease Week runs from 18-24 September this year. A collaborative "Bake it Green" event is being held between members of the MBU and MitoCamb . We are contributing green cookies, cakes or healthy green options for exhibit and photo sessions....and, of course, for tasting! Daily images will be uploaded...

Research grant awarded to Michal Minczuk and collaborators

6 September 2022

Congratulations to Michal Minczuk, Pedro Pinheiro and their collaborators, who have been awarded a grant to continue their research on maternally inherited Leigh syndrome (MILS). Cure ATP6 (a Rare Village Foundation Fund) and Cure Mito Foundation are excited to announce the collaboration between the groups of Dr. Michal...

Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury

2 September 2022

A collaborative research study led by Professors Mike Murphy (MBU) and Thomas Krieg ( Experimental Medicine and Immunotherapeutics [EMIT] ) has been published in Circulation Research and is the subject of an Editorial comment . The mitochondrial metabolite succinate drives the ischemia/reperfusion (IR) injury occurring in...

Camila Cimadamore-Werthein awarded EMBO Poster Prize

2 September 2022

Congratulations to Camila Cimadamore-Werthein, who was awarded a poster prize at the recent EMBO Workshop on Membrane transporters as essential elements of cellular function and homeostasis . Camila's poster is entitled, The human mitochondrial ADP/ATP carrier operates by a ping-pong kinetic mechanism and represents the...

Early data presented at The Champ Foundation's 3rd Pearson Syndrome Conference

25 July 2022

On Saturday, 9 July 2022, Drs Michal Minczuk, leader of the MBU's Mitochondrial Genetics research group and Pedro Silva-Pinheiro, postdoctoral researcher in this group, attended The Champ Foundation's 3rd Pearson Syndrome Conference at Mitochondrial Medicine Center, Children’s Hospital of Philadelphia (CHOP) . Pearson...

Reducing pdzd8-mediated MERCs in vivo using Drosophila slows age-associated decline in locomotor activity

15 July 2022

Mitochondria-endoplasmic reticulum (ER) contact sites (MERCs) orchestrate many important cellular functions including regulating mitochondrial quality control through mitophagy and mediating mitochondrial calcium uptake. In a new paper from the Mitochondrial Neurodegeneration group , Dr Victoria Hewitt , with other members...

Identification of the substrate binding mechanism of the mitochondrial ADP/ATP carrier

28 June 2022

The results of a research study carried out by members of the MBU's group on Mitochondrial Transport Processes , published in Nature Communications , has identified the substrate binding mechanism of the ADP/ATP carrier, also called adenine nucleotide translocase. These transport proteins have unique features that enable...

Mitochondrial DNA migrate into the nuclear genome

Pretzel Therapeutics Launches as a new Start Up

Career Development Opportunites for Experienced Postdocs!

Baking it Green for World Mitochondrial Disease Week

Research grant awarded to Michal Minczuk and collaborators

Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury

Camila Cimadamore-Werthein awarded EMBO Poster Prize

Early data presented at The Champ Foundation's 3rd Pearson Syndrome Conference

Reducing pdzd8-mediated MERCs in vivo using Drosophila slows age-associated decline in locomotor activity

Identification of the substrate binding mechanism of the mitochondrial ADP/ATP carrier

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