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MRC Mitochondrial Biology Unit


A review authored by members of Professor Judy Hirst’s research group has been announced as one of Current Opinion in Structural Biology’s best papers of 2022.


"Making the leap from structure to mechanism: are the open states of mammalian complex I identified by cryoEM resting states or catalytic intermediates?" by Injae Chung, Daniel N. Grba, John J. Wright, Judy Hirst explores different mechanistic interpretations of the closed and open states identified in cryoEM analyses of mammalian complex I.


Articles are nominated for the COSP Best Paper Awards by the corresponding Section Editors and voted for by the Editors-in-Chief. They are chosen based on originality, impact, and scientific rigor.