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MRC Mitochondrial Biology Unit


Professor Michal Minczuk, leader of the MBU’s Mitochondrial Genetics programme, Dr Jelle van den Ameele, leader of the Mitochondria in Development group and MBU associates - Professors Rita Horvath and Patrick Yu Wai Man, are excited to be key partners in the LifeArc Centre for Rare Mitochondrial Diseases.

The LifeArc Centre for Rare Mitochondrial Diseases is a national partnership with the Lily Foundation and Muscular Dystrophy UK. It is one of four research centres that will unlock new tests, treatment and cures for people living with rare diseases.

The Centre will be led by Professor Patrick Chinnery, Professor of Neurology at the University of Cambridge and Honorary Consultant Neurologist at Cambridge University Hospitals NHS Trust, and key partners at University College London, Newcastle University and three other centres (Oxford, Birmingham and Manchester).

University of Cambridge coverage

LifeArc press release

UCL Queen Square Institute of Neurology coverage

TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease.
Van Haute L et al.  Minczuk M, Horvath R. Nat Commun. 2023 Feb 23;14(1):1009.
doi: 10.1038/s41467-023-36277-7. PMID: 36823193