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MRC Mitochondrial Biology Unit


Pradeep Sheokand











Dr. Pradeep Sheokand earned his Ph.D. in parasitology from the International Centre for Genetic Engineering and Biotechnology (ICGEB) in New Delhi, India. His doctoral research focused on the functional characterization of lysophospholipase-like proteins in Plasmodium falciparum, unveiling their crucial role in lipid metabolism. Dr. Sheokand identified specific inhibitors with promising parasitical efficacies, holding potential for novel antimalarials.

Following his Ph.D., Dr. Sheokand joined Prof. Lilach Sheiner's group at the Wellcome Centre for Integrative Parasitology, Glasgow for postdoctoral research. There, he initiated a project on the functional and structural characterization of complex III of the mitochondrial electron transport chain in Plasmodium. Using inducible depletion, he demonstrated the essential role of Rieske and complex III in asexual blood stage parasite survival and gametocyte maturation. His contributions included the development and standardization of various mitochondrial biology techniques, leading to the successful purification of Plasmodium complex III, with ongoing efforts towards elucidating its structure.

Current Research Interest

With nine years of experience in parasite research, he recently joined Dr. Kasparas Petkevicius's lab as a postdoctoral researcher to explore a new avenue of research. His current work focuses on understanding how phospholipid-remodelling proteins regulate mitochondrial membrane phospholipid composition, mitochondrial dynamics, mito-ER contacts, respiration, and the mitochondrial stress response.