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MRC Mitochondrial Biology Unit

 
Read more at: Michal Minczuk's research highlighted in The Guardian

Michal Minczuk's research highlighted in The Guardian

27 June 2022

In an article published in The Guardian (The Observer - Medical Science) on Sunday, 26 June 2022, Dr David Cox highlights the research undertaken at the MBU by Dr Michal Minczuk and his colleagues, particularly in the areas of mitochondrial diseases where mutant mtDNA is genetically inherited.


Read more at: Bottisham Primary School: Science Day

Bottisham Primary School: Science Day

27 June 2022

On Thursday, 23 June, members of the MBU participated in Bottisham Primary School's Science Day. We took a variety of games and activities for three carousel sessions for students in years 5 and 6 (ages 9-11 years) and they learned about mitochondria, mitochondrial DNA, energy conversion and fruit flies. The children asked...


Read more at: Tumour necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport

Tumour necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport

24 June 2022

The results of a collaborative research study involving MRC MBU members have been published in Science . The study was led by Professor Lalita Ramakrishnan (Group Leader in the MRC Laboratory of Molecular Biology's Cell Biology Division and Head of the University of Cambridge’s Molecular Immunity Unit (housed at the LMB)...


Read more at: Professor Sir John Walker receives Cambridge Honorary Doctorate

Professor Sir John Walker receives Cambridge Honorary Doctorate

23 June 2022

Congratulations to Professor Sir John Walker, FRS , Emeritus Director of the MBU and Fellow of Sidney Sussex College , who received the Honorary Degree of Doctor of Science honoris causa from the University of Cambridge yesterday - 22 June - at a ceremony that was previously postponed due to COVID-19. The Chancellor of the...


Read more at: Identification of TMEM63C as a new motor neurone degenerative disease gene

Identification of TMEM63C as a new motor neurone degenerative disease gene

20 June 2022

The membrane contact sites between the endoplasmic reticulum (ER) and the mitochondria, called mitochondria-ER contact sites (MERCs), are dynamic signalling platforms essential for cellular viability. Indeed, MERCs are not only required to maintain mitochondrial membrane integrity by regulating the biogenesis and...


Read more at: MBU postdoctoral scientist develops ggplot2 graphics tutorial

MBU postdoctoral scientist develops ggplot2 graphics tutorial

16 May 2022

Lyuba Bozhilova is a postdoctoral bioinfomatician at the MRC MBU, who also curates our " MRC MBU Postdocs " Twitter account. Lyuba originally developed this ggplot2 tutorial for members of MitoCAMB and later expanded it to a workshop for members of the the MBU. This tutorial is aimed for research scientists with some...


Read more at: MRC National Mouse Genetics Network - MitoCluster

MRC National Mouse Genetics Network - MitoCluster

21 April 2022

We are really excited to announce that four of our research group leaders – Drs Michal Minczuk , Jelle van den Ameele , Alex Whitworth and Professor Patrick Chinnery - are participating in the MRC National Mouse Genetics Network (NMGN) and a part of a cluster focussing on mitochondrial medicine - MitoCluster . MitoCluster...


Read more at: Drug Discovery News – showcase featuring Michal Minczuk

Drug Discovery News – showcase featuring Michal Minczuk

14 April 2022

For an article by Danielle Gerhard PhD, entitled “ On the road to treating mitochondrial disease ”, which was published in late 2021 in Drug Discovery News , Dr Michal Minczuk was interviewed on his modified zinc finger nuclease technology to target specific sequences in mitochondrial DNA. Professor Carlos Moraes (...


Read more at: Genomics Unravelled Podcast Series: Mitochondrial genomics

Genomics Unravelled Podcast Series: Mitochondrial genomics

13 April 2022

In Episode 5 of the Genomics Unravelled podcast series Professor Patrick Chinnery talks about the challenges of diagnosing patients with mitochondrial diseases, the diagnostic power of genomics and developing new treatments for rare diseases.


Read more at: Launch of our MITOTrumps card game

Launch of our MITOTrumps card game

31 March 2022

We are excited to launch our new MITOTrumps card game as this year’s contribution to the Cambridge Festival . MITOTrumps is a card game for all ages, based on mitochondrial proteins, to introduce scientists and non-scientists alike to the exciting world of mitochondrial protein biology . On each card there is an image of a...