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MRC Mitochondrial Biology Unit

 
Read more at: MBU postdoctoral scientist develops ggplot2 graphics tutorial

MBU postdoctoral scientist develops ggplot2 graphics tutorial

16 May 2022

Lyuba Bozhilova is a postdoctoral bioinfomatician at the MRC MBU, who also curates our " MRC MBU Postdocs " Twitter account. Lyuba originally developed this ggplot2 tutorial for members of MitoCAMB and later expanded it to a workshop for members of the the MBU. This tutorial is aimed for research scientists with some...


Read more at: MRC National Mouse Genetics Network - MitoCluster

MRC National Mouse Genetics Network - MitoCluster

21 April 2022

We are really excited to announce that four of our research group leaders – Drs Michal Minczuk , Jelle van den Ameele , Alex Whitworth and Professor Patrick Chinnery - are participating in the MRC National Mouse Genetics Network (NMGN) and a part of a cluster focussing on mitochondrial medicine - MitoCluster . MitoCluster...


Read more at: Drug Discovery News – showcase featuring Michal Minczuk

Drug Discovery News – showcase featuring Michal Minczuk

14 April 2022

For an article by Danielle Gerhard PhD, entitled “ On the road to treating mitochondrial disease ”, which was published in late 2021 in Drug Discovery News , Dr Michal Minczuk was interviewed on his modified zinc finger nuclease technology to target specific sequences in mitochondrial DNA. Professor Carlos Moraes (...


Read more at: Genomics Unravelled Podcast Series: Mitochondrial genomics

Genomics Unravelled Podcast Series: Mitochondrial genomics

13 April 2022

In Episode 5 of the Genomics Unravelled podcast series Professor Patrick Chinnery talks about the challenges of diagnosing patients with mitochondrial diseases, the diagnostic power of genomics and developing new treatments for rare diseases.


Read more at: Launch of our MITOTrumps card game

Launch of our MITOTrumps card game

31 March 2022

We are excited to launch our new MITOTrumps card game as this year’s contribution to the Cambridge Festival . MITOTrumps is a card game based on mitochondrial proteins. On each card there is an image of a mitochondrial protein, along with numerical statistics relating to that protein - amino acid number, mutations (the...


Read more at: Collaboration with Nigerian researchers evaluating the neuroprotective potential of natural products

Collaboration with Nigerian researchers evaluating the neuroprotective potential of natural products

28 March 2022

As an alternative to expensive pharmaceuticals, there is broad interest in the developing world to evaluate the therapeutic potential of natural compounds for widespread, debilitating diseases. As part of our ongoing effort to engage with a broader scientific community, Dr Alex Whitworth (Mitochondrial Neurodegeneration)...


Read more at: Nature Reviews Genetics - featured article for April

Nature Reviews Genetics - featured article for April

22 March 2022

The Editorial Team at Nature Reviews Genetics has chosen the recent review by Pedro Silva-Pinheiro and Michal Minczuk as the Journal's featured article for the April issue . The review, entitled The potential of mitochondrial genome engineering , reflects on the past, present and future of mitochondrial genome engineering...


Read more at: Identification of a key checkpoint during mitoribosomal large subunit (mtLSU) assembly

Identification of a key checkpoint during mitoribosomal large subunit (mtLSU) assembly

17 February 2022

In a collaborative research article published today in Nature Communications , Pedro Rebelo-Guiomar and MBU colleagues from the research groups of Drs Michal Minczuk and Alex Whitworth at the MBU report the identification of a key checkpoint during mtLSU assembly, which is essential to maintaining mitochondrial homeostasis...


Read more at: Potential for gene-editing to tackle mitochondria disorders

Potential for gene-editing to tackle mitochondria disorders

8 February 2022

A research article published today (8 February 2022) in Nature Communications describes how Pedro Silva-Pinheiro and colleagues from the Mitochondrial Genetics Group led by Dr Michal Minczuk at the MBU were able to edit the mitochondrial DNA of live mice. The researchers used a biological tool, known as a mitochondrial...


Read more at: Professors Patrick Chinnery and John Walker to deliver the XIII Oon Lecture

Professors Patrick Chinnery and John Walker to deliver the XIII Oon Lecture

25 January 2022

Professors Patrick Chinnery and John Walker will deliver the XIII Oon Lecture, "Mitochondria: from molecules to medicine" at Downing College (Howard Theatre) at 6.00 pm on Tuesday, 15 February 2022. The lecture was streamed live and the recording is available on YouTube (21 February).