skip to content

MRC Mitochondrial Biology Unit

 
Read more at: World Mitochondrial Disease Week

World Mitochondrial Disease Week

13 September 2020

mito-facts6.jpg This week, 13-19 September 2020 is World Mitochondrial Disease Week . An initiative of International Mito Patients (IMP), World Mitochondrial Disease Week raises awareness of mitochondrial disease (mito) on a global scale through educational, fundraising and advocacy activities. As we have not been able to...


Read more at: John Walker's group solves the structure of the dimeric ATP synthase from bovine mitochondria at atomic resolution

John Walker's group solves the structure of the dimeric ATP synthase from bovine mitochondria at atomic resolution

9 September 2020

Tobias Spikes, Martin Montgomery and John Walker have solved the atomic resolution structure of dimeric ATP synthase from bovine mitochondria by cryo-electron microscopy. The ATP synthases are complex molecular machines embedded in the inner membranes of mitochondria where they produce almost all the ATP required to...


Read more at: MBU volunteers involved in Covid-19 testing

MBU volunteers involved in Covid-19 testing

7 September 2020

Volunteers from the MBU have been involved in the collaborative COVID-19 testing operation, based at the Cambridge Testing Centre in Partnership with AstraZeneca and GSK. Charis Goodyear has been talking to volunteers from across the Biomedical Campus, who joined the testing team when they were not able to carry out their...


Read more at: MitoQ can prevent heart disease before birth

MitoQ can prevent heart disease before birth

19 August 2020

The results of a research study involving MitoQ – a mitochondrial antioxidant developed by the MBU’s Professor Mike Murphy , who also participated in the research study, have been published in Science Advances .


Read more at: Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation

Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation

3 August 2020

dsc_0068_dan-lab2-web.png These exciting results of research carried out in the MBU’s Mitochondrial Complex I Group, led by Professor Judy Hirst , have been published in Nature Structural & Molecular Biology . Daniel Grba, PhD student and first author, gives this overview of the key findings: Using single-particle cryo...


Read more at: MRC Cambridge Activity Book

MRC Cambridge Activity Book

7 July 2020

UKRI Medical Research Council (MRC) scientists in Cambridge are studying all the different ways that medical science can help protect our health and improve our lives. This activity book is for people of all ages to explore the variety of MRC-funded work that takes place in Cambridge. Our work involves examining everything...


Read more at: Potential for nanovesicles to sustain artificial cells

Potential for nanovesicles to sustain artificial cells

16 June 2020

The results of a research project entitled, “ Bottom-Up Construction of a Minimal System for Cellular Respiration and Energy Regeneration ” have been published in ACS Synthetic Biology. This research was carried out at the MBU, in the Complex I Group, led by Professor Judy Hirst . It describes the bottom-up assembly and...


Read more at: MBU open for research

MBU open for research

15 June 2020

The MBU and the Keith Peters Building reopened for research today (Monday, 15 June), with those researchers present following strict University-approved protocols to protect both them and the wider community during the COVID-19 crisis. While everyone will continue to work from home whenever possible, we are delighted at...


Read more at: The MBU welcomes Dr Jelle van den Ameele

The MBU welcomes Dr Jelle van den Ameele

26 May 2020

The MBU is delighted to welcome Dr Jelle van den Ameele - a new Wellcome Clinical Research Career Development Fellow, who will start to build his independent research group under our roof. Jelle’s Research is focused on molecular mechanisms of tissue specificity in mitochondrial disease. He brings both clinical and...


Read more at: Mike Murphy awarded Wellcome Trust Joint Investigator Award

Mike Murphy awarded Wellcome Trust Joint Investigator Award

22 May 2020

We are excited to share the news that Professors Mike Murphy (MBU, Cambridge) and Richard Hartley (Glasgow) have been awarded a Wellcome Trust Joint Investigator Award of £1.6 milion for a research project entitled, ‘Exploring mitochondrial metabolism in health and disease using targeted biological chemistry’. The project...